☆ 4.6 Editorial Material

Interferons in hematopoiesis and leukemia

ONCOIMMUNOLOGY (2013)

期刊

ONCOIMMUNOLOGY

卷 2, 期 6, 页码 -

出版社

LANDES BIOSCIENCE

DOI: 10.4161/onci.24572

关键词

interferon; hematopoiesis; leukemia; hematopoietic stem cells; leukemia stem cells

类别

Oncology Immunology

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摘要

Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia.

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