期刊
ONCOIMMUNOLOGY
卷 1, 期 6, 页码 979-981出版社
LANDES BIOSCIENCE
DOI: 10.4161/onci.20172
关键词
adenoviruses; oncolytic adenoviruses; immunotherapy; oncoimmunology; immunovirotherapy
The therapeutic efficacy of oncolytic viruses including adenovirus has been thought to depend mostly on direct viral destruction of tumor cells. However, this view has changed with the discovery that oncolysis can also induce innate and antigen-specific adaptive immunity against the tumor. Here we summarize our findings from cancer patients.
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