期刊
ONCOIMMUNOLOGY
卷 1, 期 9, 页码 1629-1631出版社
LANDES BIOSCIENCE
DOI: 10.4161/onci.21652
关键词
breast cancer; CD137; CD40; immunotherapy; PD-1; radiotherapy; T cells
The development and use of combination immunotherapy-based anticancer regimens is at an early but clearly exciting stage. We now demonstrate that the antibody-based co-targeting of multiple immunostimulatory and/or inhibitory pathways can be used safely and effectively in combination with single dose or fractionated radiotherapy to cure mice bearing established mammary tumors.
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