期刊
ONCOIMMUNOLOGY
卷 1, 期 9, 页码 1650-1651出版社
LANDES BIOSCIENCE
DOI: 10.4161/onci.21970
关键词
immune suppression; immunotherapy; lung cancer; myeloid-derived suppressor cells
资金
- NCATS NIH HHS [UL1 TR000124] Funding Source: Medline
Myeloid-derived suppressor cells (MDSCs) are important regulators of immune responses. These cells suppress the cytotoxic activities of natural killer (NK)-cell and T-cell effectors and promote tumor growth. We demonstrated that depleting MDSCs improve therapeutic responses to vaccination in a murine model of lung cancer. This approach may prove beneficial against tumors in which MDSC exert prominent immunosuppressive effects.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据