Article
Neurosciences
Bo Li, Shufen Zhang, Shuyan Li, Kai Liu, Xiaoming Hou
Summary: This study found evidence of abnormal regional functional activity and connectivity within brain regions in postpartum depression (PPD), which may contribute to a better understanding of the neuropathology underlying PPD.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Fan Yang, Wenxiao Jia, Hanjiaerbieke Kukun, Shuang Ding, Haotian Zhang, Yunling Wang
Summary: This study investigated the resting brain function in patients with TLE-N using rs-fMRI analysis methods. The results showed that cTLE-N patients exhibited brain activity changes in visual functional areas, while rTLE-N patients showed brain activity changes in the prefrontal limbic system and default mode network. Different epilepsy networks exist between cTLE-N and rTLE-N.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Psychiatry
Kun Shu, Xinjian Ye, Jiawen Song, Xiaoyan Huang, Shihan Cui, Yongjin Zhou, Xiaozheng Liu, Lu Han, Zhihan Yan, Kun Liu
Summary: This study aimed to investigate the alterations in brain neural activity and functional connectivity (FC) in male patients with non-alcoholic fatty liver disease (NAFLD) and their relationship with cognitive performance. Resting-state functional magnetic resonance imaging scans and neuropsychological examinations were conducted on NAFLD patients and controls. The results showed that NAFLD patients exhibited altered neural activity in specific brain regions and altered FC between the salience network and the default mode network (DMN).
Article
Clinical Neurology
Lei Li, Jiayu Liu, Fenxiong Liang, Haidong Chen, Rungen Zhan, Shengli Zhao, Tiao Li, Yongjun Peng
Summary: This study used rs-fMRI measures to investigate changes in brain function activity in patients with dysphagia after cerebral infarction (DYS) and their correlations with dysphagia severity. The results showed that the changes in brain function activity in the right temporal and left parietal lobes were associated with dysphagia severity in DYS patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neuroimaging
Varina L. Boerwinkle, Bethany L. Sussman, Sarah N. Wyckoff, Iliana Manj, Justin M. Fine, David Adelson
Summary: This study aimed to distinguish seizure onset zones (SOZ) from propagation zones (pZ) using resting state fMRI effective connectivity (RSEC) and found an association between age and RSEC, as well as changes in signal modulation from pre-to-post surgery.
NEUROIMAGE-CLINICAL
(2022)
Article
Endocrinology & Metabolism
Yingwen Miao, Jin Wang, Bing Zhang, Wen Zhang, Xiang Xu, Yingjiao Hou, Qun Ding, Congcong Yu, Zhou Zhang, Yan Bi, Dalong Zhu
Summary: This study aimed to investigate the clinical features and spontaneous brain activity of patients with LADA and their relationship. The results showed that patients with LADA had worse cognitive function and decreased brain activity compared to controls, and these changes were closely related to glycolipid metabolism.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Neurosciences
Olli Rajasilta, Suvi Hakkinen, Malin Bjornsdotter, Noora M. Scheinin, Satu J. Lehtola, Jani Saunavaara, Riitta Parkkola, Tuire Lahdesmaki, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari
Summary: Prenatal stress exposure may have a programming effect on the developing infant brain, affecting temperament, cognitive functions, and psychiatric disorder risk. Maternal psychological distress during the 24th gestational week was found to be positively associated with neonate brain features, specifically in the medial prefrontal cortex. These findings suggest that prenatal stress exposure can impact the functional development of the brain during gestation.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Yawen Liu, Haijun Niu, Tingting Zhang, Linkun Cai, Dong Liu, Erwei Zhao, Liang Zhu, PengGang Qiao, Wei Zheng, Pengling Ren, Zhenchang Wang
Summary: This study aimed to explore the association between cardiovascular and spontaneous brain activities during dobutamine infusion in healthy young adults. The results showed that blood pressure and heart rate significantly increased after dobutamine infusion, and there was a decrease in brain functional activity in certain regions. These findings suggest that brain-heart interactions exist in healthy young adults under acute cardiovascular alterations.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Marlena Duda, Danai Koutra, Chandra Sripada
Summary: This study investigates the presence of dynamic functional connectivity during rest and proposes a data-driven framework for studying cognitive neuroscience questions using connectivity changes. The framework outperforms the traditional sliding window approach in accuracy and computational efficiency when applied to working memory task data. Additionally, when applied to resting state fMRI data, the method consistently identifies five reliable FC states which show significant correlation with behavioral phenotypes.
HUMAN BRAIN MAPPING
(2021)
Article
Geriatrics & Gerontology
Lei Wang, Rui Zhu, Xiao Zhou, Zhiyong Zhang, Dantao Peng
Summary: This study found that sleep disturbances in mild Alzheimer's disease patients were associated with decreased local and remote functional connectivity, particularly in the primary sensory and visual networks. These findings are important for understanding the relationship between sleep disorders and cognitive impairment.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Neurosciences
Balu Krishnan, Simon Tousseyn, Zhong Irene Wang, Hiroatsu Murakami, Guiyun Wu, Richard Burgess, Leonidas Iasemidis, Imad Najm, Andreas V. V. Alexopoulos
Summary: This study aims to investigate the functional connectivity in brain regions during seizures using MEG and SPECT data. The results showed that brain regions exhibiting hyperperfusion or hypoperfusion during seizures were strongly correlated with functional connectivity. Additionally, high connectivity was observed between hyperperfused regions both inside and outside the resected area, and between regions of ictal hypoperfusion.
HUMAN BRAIN MAPPING
(2023)
Article
Neurosciences
Shengwen Deng, Crystal G. Franklin, Michael O'Boyle, Wei Zhang, Betty L. Heyl, Paul A. Jerabek, Hanzhang Lu, Peter T. Fox
Summary: The study aims to quantify spatial correspondences between voxel-based physiological (VBP) variables derived from blood oxygen level dependent (BOLD) fMRI and PET measurements of cerebral metabolic rate and hemodynamics. The results show significant correspondences between ALFF and blood volume (BV), between fALFF and metabolic rate of glucose (MRGlu), oxygen consumption (MRO2), blood flow (BF) and BV, as well as between ReHo and MRGlu, MRO2, BF, and BV. However, the strength of the PET-BOLD correspondences varies by brain region.
Article
Neurosciences
Nicholas A. Hubbard, Monroe P. Turner, Kevin R. Sitek, Kathryn L. West, Jakub R. Kaczmarzyk, Lyndahl Himes, Binu P. Thomas, Hanzhang Lu, Bart Rypma
Summary: By using calibrated functional magnetic resonance imaging, this study found that low-frequency fluctuations of cerebral metabolic rate of oxygen (CMRO2) during resting state exhibited organizational properties similar to previous functional and anatomical connectivity studies. Furthermore, voxel-wise CMRO2 connectivity showed spatial patterns consistent with four specific resting-state subnetworks.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Adrian Andrzej Chrobak, Bartosz Bohaterewicz, Anna Maria Sobczak, Magdalena Marszal-Wisniewska, Anna Tereszko, Anna Krupa, Anna Ceglarek, Magdalena Fafrowicz, Amira Bryll, Tadeusz Marek, Dominika Dudek, Marcin Siwek
Summary: This study compared the baseline brain activity in euthymic bipolar disorder patients with healthy controls using various rs-fMRI analyses. Significant differences in ALFF, f/ALFF, slow-5, and ReHo were found between the two groups, suggesting distinct patterns of brain activity in BD patients compared to HC. The combination of different rs-fMRI methods may provide a more comprehensive understanding of the complex resting state abnormalities in bipolar disorder.
Article
Neurosciences
Giovanni Pellegrino, Anna-Lisa Schuler, Giorgio Arcara, Giovanni Di Pino, Francesco Piccione, Eliane Kobayashi
Summary: This study investigated the impact of EPI noise on resting state activity and connectivity using MEG. Results showed that both fMRI and white noise reduced connectivity of cortical networks, with specific effects in the auditory and sensory-motor networks for fMRI noise. Theta-delta activity related to drowsiness correlated positively with variations in cortical connectivity.
Article
Biochemical Research Methods
Bingni W. Brunton, Lise A. Johnson, Jeffrey G. Ojemann, J. Nathan Kutz
JOURNAL OF NEUROSCIENCE METHODS
(2016)
Article
Neurosciences
Kurt E. Weaver, Jeremiah D. Wander, Andrew L. Ko, Kaitlyn Casimo, Thomas J. Grabowski, Jeffrey G. Ojemann, Felix Darvas
Article
Clinical Neurology
Robert Buckley, Samuel Estronza-Ojeda, Jeffrey G. Ojemann
NEUROSURGERY CLINICS OF NORTH AMERICA
(2016)
Article
Acoustics
Felix Darvas, Edin Mehic, Connor J. Caler, Jeff G. Ojemann, Pierre D. Mourad
ULTRASOUND IN MEDICINE AND BIOLOGY
(2016)
Article
Biochemical Research Methods
Kai J. Miller, Gerwin Schalk, Dora Hermes, Jeffrey G. Ojemann, Rajesh P. N. Rao
PLOS COMPUTATIONAL BIOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Andrew S. Allen, Samuel F. Berkovic, Joshua Bridgers, Patrick Cossette, Dennis Dlugos, Michael P. Epstein, Tracy Glauser, David B. Goldstein, Erin L. Heinzen, Yu Jiang, Michael R. Johnson, Ruben Kuzniecky, Daniel H. Lowenstein, Anthony G. Marson, Heather C. Mefford, Terence J. O'Brien, Ruth Ottman, Steven Petrou, Slave Petrovski, Annapurna Poduri, Zhong Ren, Ingrid E. Scheffer, Elliott Sherr, Quanli Wang, Rudi Balling, Nina Barisic, Stephanie Baulac, Hande Caglayan, Dana Craiu, Peter De Jonghe, Christel Depienne, Renzo Guerrini, Ingo Helbig, Helle Hjalgrim, Dorota Hoffman-Zacharska, Johanna Jaehn, Karl Martin Klein, Bobby Koeleman, Vladimir Komarek, Roland Krause, Eric Leguern, Anna-Elina Lehesjoki, Johannes R. Lemke, Holger Lerche, Tarja Linnankivi, Carla Marini, Patrick May, Rikke S. Moller, Hiltrud Muhle, Deb Pal, Aarno Palotie, Felix Rosenow, Kaja Selmer, Jose M. Serratosa, Sanjay Sisodiya, Ulrich Stephani, Katalin Sterbova, Pasquale Striano, Arvid Suls, Tiina Talvik, Sarah von Spiczak, Yvonne Weber, Sarah Weckhuysen, Federico Zara, Bassel Abou-Khalil, Brian K. Alldredge, Dina Amrom, Eva Andermann, Frederick Andermann, Jocelyn F. Bautista, Samuel F. Berkovic, Judith Bluvstein, Gregory D. Cascino, Damian Consalvo, Patricia Crumrine, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Miguel E. Fiol, Nathan B. Fountain, Jacqueline French, Daniel Friedman, Tracy Glauser, Kevin Haas, Sheryl R. Haut, Jean Hayward, Sucheta Joshi, Andres Kanner, Heidi E. Kirsch, Eric H. Kossoff, Rachel Kuperman, Ruben Kuzniecky, Daniel H. Lowenstein, Shannon M. McGuire, Paul V. Motika, Edward J. Novotny, Ruth Ottman, Juliann M. Paolicchi, Jack Parent, Kristen Park, Annapurna Poduri, Ingrid E. Scheffer, Renee A. Shellhaas, Elliott Sherr, Joseph Sirven, Michael C. Smith, Joseph Sullivan, Liu Lin Thio, Anu Venkat, Eileen P. G. Vining, Gretchen K. Von Allmen, Judith L. Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer
EUROPEAN JOURNAL OF HUMAN GENETICS
(2017)
Article
Clinical Neurology
Andrew S. Allen, Susannah T. Bellows, Samuel F. Berkovic, Joshua Bridgers, Rosemary Burgess, Gianpiero Cavalleri, Seo-Kyung Chung, Patrick Cossette, Norman Delanty, Dennis Dlugos, Michael P. Epstein, Catharine Freyer, David B. Goldstein, Erin L. Heinzen, Michael S. Hildebrand, Michael R. Johnson, Ruben Kuzniecky, Daniel H. Lowenstein, Anthony G. Marson, Richard Mayeux, Caroline Mebane, Heather C. Mefford, Terence J. O'Brien, Ruth Ottman, Steven Petrou, Slave Petrovski, William O. Pickrell, Annapurna Poduri, Rodney A. Radtke, Mark I. Rees, Brigid M. Regan, Zhong Ren, Ingrid E. Scheffer, Graeme J. Sills, Rhys H. Thomas, Quanli Wang, Bassel Abou-Khalil, Brian K. Alldredge, Dina Amrom, Eva Andermann, Frederick Andermann, Jocelyn F. Bautista, Samuel F. Berkovic, Judith Bluvstein, Alex Boro, Gregory D. Cascino, Damian Consalvo, Patricia Crumrine, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Miguel Fiol, Nathan B. Fountain, Jacqueline French, Catharine Freyer, Daniel Friedman, Eric B. Geller, Tracy Glauser, Simon Glynn, Kevin Haas, Sheryl R. Haut, Jean Hayward, Sandra L. Helmers, Sucheta Joshi, Andres Kanner, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rachel Kuperman, Ruben Kuzniecky, Daniel H. Lowenstein, Paul V. Motika, Edward J. Novotny, Ruth Ottman, Juliann M. Paolicchi, Jack M. Parent, Kristen Park, Annapurna Poduri, Lynette G. Sadleir, Ingrid E. Scheffer, Renee A. Shellhaas, Elliott H. Sherr, Jerry J. Shih, Shlomo Shinnar, Rani K. Singh, Joseph Sirven, Michael C. Smith, Joseph Sullivan, Liu Lin Thio, Anu Venkat, Eileen P. G. Vining, Gretchen K. Von Allmen, Judith L. Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer
Editorial Material
Clinical Neurology
Edward J. Novotny
Article
Pediatrics
Anne T. Berg, Jason Coryell, Russell P. Saneto, Zachary M. Grinspan, John J. Alexander, Mariana Kekis, Joseph E. Sullivan, Elaine C. Wirrell, Renee A. Shellhaas, John R. Mytinger, William D. Gaillard, Eric H. Kossoff, Ignacio Valencia, Kelly G. Knupp, Courtney Wusthoff, Cynthia Keator, William B. Dobyns, Nicole Ryan, Tobias Loddenkemper, Catherine J. Chu, Edward J. Novotny, Sookyong Koh
Article
Clinical Neurology
Anthony C. Wang, George M. Ibrahim, Andrew V. Poliakov, Page I. Wang, Aria Fallah, Gary W. Mathern, Robert T. Buckley, Kelly Collins, Alexander G. Weil, Hillary A. Shurtleff, Molly H. Warner, Francisco A. Perez, Dennis W. Shaw, Jason N. Wright, Russell P. Saneto, Edward J. Novotny, Amy Lee, Samuel R. Browd, Jeffrey G. Ojemann
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2018)
Article
Clinical Neurology
Kurt E. Weaver, Andrew Poliakov, Edward J. Novotny, Jared D. Olson, Thomas J. Grabowski, Jeffrey G. Ojemann
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2018)
Article
Neurosciences
Nancy X. R. Wang, Jared D. Olson, Jeffrey G. Ojemann, Rajesh P. N. Rao, Bingni W. Brunton
FRONTIERS IN HUMAN NEUROSCIENCE
(2016)
Article
Engineering, Biomedical
L. Bashford, J. Wu, D. Sarma, K. Collins, R. P. N. Rao, J. G. Ojemann, C. Mehring
JOURNAL OF NEURAL ENGINEERING
(2018)
Article
Behavioral Sciences
Sabra Zaraa, H. Steve White, Andy Stergachis, Edward Novotny Jr, Chris Protos, Grant Simic, Jennifer L. Bacci
Summary: This study used design thinking to develop a community pharmacist-led intervention for people living with epilepsy. Four features - pharmacist-patient consultations, care plan development, regular check-ins, and care coordination with other health care providers - were identified as desirable, feasible, and viable for the intervention. The study highlights the importance of involving pharmacists in epilepsy care and provides evidence-based features for such interventions.
EPILEPSY & BEHAVIOR
(2024)
Article
Clinical Neurology
Kelly L. Collins, Devapratim Sarma, Shahin Hakimian, Jeff J. Tsai, Jeffrey G. Ojemann
EPILEPSY & BEHAVIOR CASE REPORTS
(2019)