期刊
FRONTIERS OF MEDICINE
卷 7, 期 2, 页码 223-230出版社
SPRINGER
DOI: 10.1007/s11684-013-0252-8
关键词
microRNA; adipocyte; differentiation; adipogenesis
Adipocytes differentiate from mesenchymal stem cells (MSCs) in a process known as adipogenesis. The programme of adipogenesis is regulated by the sequential activation of transcription factors and several signaling pathways. There is growing evidence indicating that a class of small non-coding single-stranded RNAs known as microRNAs (miRNAs) also are involved in this process. In this review, we summarize the biology and functional mechanisms of miRNAs in adipocyte differentiation. In addition, we further discuss the miRNAs profiling, the miRNAs function and miRNAs target prediction in the adipogenesis.
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