Article
Engineering, Multidisciplinary
Mario Ignacio Simoy, Maria Veronica Simoy, Graciela Ana Canziani
Summary: The study developed a model to simulate the population dynamics of a cattle herd based on age and sex structure, considering the effects of movements between districts on the local dynamics and herd structure. By analyzing the impact of different management practices, the model can help improve the profitability of livestock systems.
APPLIED MATHEMATICAL MODELLING
(2021)
Article
Multidisciplinary Sciences
Ruozhu Han, Monique Mourits, Wilma Steeneveld, Henk Hogeveen
Summary: This study explores the association between herd performance indicators and dairy cow longevity under Dutch production conditions. The results show that only four herd performance indicators are significantly associated with all three longevity measures. However, the strength of the associations between longevity and herd performance indicators is limited. It is also found that only a part of the observed variance in longevity among herds can be explained by the herd performance variables, suggesting that other factors such as farmers' attitude and strategic management may play a dominant role in herd-level longevity.
Article
Agriculture, Dairy & Animal Science
David J. Wilson, Emma Jane Kelly, Savannah Gucwa
Summary: Necropsy of dairy cattle is an important tool for diagnosing the cause of death. This study summarized the primary causes of death in dairy animals from Utah and other states. It found that some fatal diseases in dairy cattle could be diagnosed before death and necropsy diagnosis can guide management practices to reduce death rates in dairy herds.
Article
Biochemistry & Molecular Biology
Diana M. Cornejo-Sanchez, Guangyou Li, Tabassum Fabiha, Ran Wang, Anushree Acharya, Jenna L. Everard, Magda K. Kadlubowska, Yin Huang, Isabelle Schrauwen, Gao T. Wang, Andrew T. DeWan, Suzanne M. Leal
Summary: Age-related hearing loss (ARHL) is a common sensory deficit in the elderly population, and both common and rare variants contribute to its etiology. Through analyzing exome and imputed data, we identified and replicated associations between ARHL and rare variants in genes KLHDC7B, PDCD6, MYO6, SYNJ2, TECTA, PUS7L, and EYA4. This study emphasizes the vital role of rare variants, including those in Mendelian nonsyndromic HL genes, in the development of ARHL.
EUROPEAN JOURNAL OF HUMAN GENETICS
(2023)
Article
Geochemistry & Geophysics
Bartosz Budzyn, Jiri Slama, Fernando Corfu, James Crowley, Mark Schmitz, Michael L. Williams, Michael J. Jercinovic, Gabriela A. Kozub-Budzyn, Patrik Konecny, Grzegorz Rzepa, Adam Wlodek
Summary: A single megacryst of Neoproterozoic monazite (TS-Mnz) was studied using various analytical techniques, revealing both unaltered and altered domains, with U-Pb and Th-Pb dating results obtained by different methods. The TS-Mnz showed relatively reproducible U-Pb, Th-Pb, and U-Th-total Pb dates, making it a potential new age reference material for in-situ U-Th-Pb microanalysis.
Article
Medical Laboratory Technology
Corey Markus, Rui Zhen Tan, Chun Yee Lim, Wayne Rankin, Susan J. Matthews, Tze Ping Loh, William M. Hague
Summary: This study investigates the use of different regression frameworks to assess the commutability between reference materials and clinical samples. The results show that selecting the appropriate regression model is crucial depending on the variance profiles.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Genetics & Heredity
Guillaume Bordet, Niraj Lodhi, Andrew Kossenkov, Alexei Tulin
Summary: An individual's gene expression profile changes throughout life, with differences in gene expression between young and old organisms driven by physiological needs and functions. Muscle development genes are mostly downregulated in older flies, while genes related to apoptosis and resistance to toxic chemicals are upregulated. Results also suggest potential functions of unknown genes in affecting lifespan.
Article
Multidisciplinary Sciences
Qingquan Liu, Yiru Wang, Zhi Chen, Xiaolin Guo, Yongman Lv
Summary: The study explored the age- and sex-specific distribution of blood urea nitrogen (BUN) levels among healthy Chinese adults, finding that BUN values differed between males and females and were positively correlated with BMI, cholesterol, and blood sugar, while negatively correlated with eGFR. Additionally, the study confirmed a positive association between BUN levels and age after adjusting for confounding factors.
SCIENTIFIC REPORTS
(2021)
Article
Biochemical Research Methods
Ming Bi, Bing Bai, Zhixin Tian
Summary: Monoclonal antibodies with various function effectors have great potential in therapy, and glycosylation, a common post-translational modification, plays a significant role in their cohesion. The study characterized the monosaccharide composition/sequence and glycan structures in mAbs through comprehensive mass spectrometry and the application of a structure-specific search engine.
JOURNAL OF PROTEOME RESEARCH
(2022)
Article
Environmental Sciences
Nobuyasu Hanari, Takeshi Nakano
Summary: Chlorinated paraffins (CPs) are industrial chemicals primarily used in metalworking fluids. Short-chain chlorinated paraffins (SCCPs) are a famous environmental pollutant, and reliable quantification of SCCPs has been a critical issue due to the large number of SCCP isomers. This study developed a novel SCCP formulation as a candidate reference material and evaluated the reliability of gas chromatography mass spectrometry (GC/MS) and liquid chromatography mass spectrometry (LC/MS) methods. The results showed comparable concentrations of SCCPs from GC and LC, indicating the effectiveness of the candidate reference material for quantification and evaluation.
Article
Medicine, General & Internal
Marie-Laure Sattolo, Laura Arbour, Marianne Bilodeau-Bertrand, Ga Eun Lee, Chantal Nelson, Nathalie Auger
Summary: This study suggests a strong association between birth defects in children and mortality due to circulatory, respiratory, and digestive causes.
Article
Public, Environmental & Occupational Health
Siddharth Chandra, Madhur Chandra
Summary: Distortions in the age distribution of deaths can be used to track pandemic activity, as they are highly correlated with the number of COVID-19 fatalities.
AMERICAN JOURNAL OF PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Oyunchimeg Buyadaa, Agus Salim, Jedidiah I. Morton, Dianna J. Magliano, Jonathan E. Shaw
Summary: The study found that in patients with type 2 diabetes, those with a younger age of onset or longer duration of the disease experienced faster declines in kidney function compared to those diagnosed in middle age or with a shorter disease duration.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Li Zhang, You-Yi Tu, Zhe Zhao, Jun Jin, Jun Tao, Xiao-Yan Zhang
Summary: This study investigated the relationship between thyroid hormone levels and all-cause mortality in sarcopenic older adults over 80 years of age. The study found that lower serum FT3 levels were associated with higher mortality in this population.
Article
Geochemistry & Geophysics
Ruby C. Marsden, Martin Danisik, Axel K. Schmitt, Kai Rankenburg, Marcel Guillong, Ung-San Ahn, Christopher L. Kirkland, Noreen J. Evans, Olivier Bachmann, Tommaso Tacchetto, Bradley J. McDonald, Hugo K. H. Olierook
Summary: U-Th disequilibrium dating method is commonly used to date zircon crystallization in volcanic and plutonic rocks, but the lack of suitable reference materials under 350 ka has been a challenge. This study introduces zircon SS14-28 from Jeju Island, South Korea as a potential reference material, with analysis showing consistent results across different laboratories. The proposed age of 82 +/- 6 ka is calculated based on a combined isochron gradient, demonstrating the accuracy and repeatability of the U-Th disequilibrium dating method.
GEOSTANDARDS AND GEOANALYTICAL RESEARCH
(2022)