Review
Biochemistry & Molecular Biology
Christopher A. Adin
Summary: Serum free bilirubin concentration has significant effects on morbidity and mortality in major health conditions such as cardiovascular disease, diabetes, and obesity/metabolic syndrome. Challenges in using bilirubin as a therapeutic agent in human patients include poor solubility, complex molecular structure, and concerns about animal-derived sources. However, advancements in drug delivery, biosynthetic strategies, and drug synthesis offer new possibilities for applying bilirubin as a pharmaceutical agent.
Article
Rehabilitation
Grace Kayola, Mataa M. Mataa, Melody Asukile, Lorraine Chishimba, Mashina Chomba, Dominique Mortel, Aparna Nutakki, Stanley Zimba, Deanna Saylor
Summary: Stroke is a major cause of disability worldwide, especially in low- and middle-income countries where access to acute stroke interventions is limited. Effective poststroke rehabilitation is crucial for promoting recovery, but faces numerous barriers in these countries. This article summarizes the challenges faced by individuals with stroke in accessing rehabilitation services, the consequences of lack of access, and potential strategies to improve access and quality of rehabilitation services in low- and middle-income countries.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Review
Biochemistry & Molecular Biology
Thembaninkosi G. Gaule, Ramzi A. Ajjan
Summary: Fibrinogen plays a crucial role in blood clotting, with alterations in its structure or incorporation of antifibrinolytic proteins potentially leading to unstable or persistent clots, increasing the risk of bleeding or thrombosis. Understanding fibrinogen function can help in developing effective therapies to modulate clotting and bleeding risk while maintaining the delicate balance between clot formation and lysis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Brianne A. Altmann, Simon Rosenau
Summary: Spirulina shows potential as a protein source in poultry and pork production, as well as aquaculture. However, using spirulina as a feed can have implications for system productivity and product quality, depending on the animal production system. Further research should focus on sustainability analysis and product processing and acceptance to investigate the trade-offs of incorporating spirulina into poultry and fish diets.
Review
Cell Biology
Chiara F. Valori, Agostino Possenti, Liliana Brambilla, Daniela Rossi
Summary: Neurodegenerative diseases are a heterogeneous group of disorders that are expected to see a significant increase in incidence in the next 30 years due to the aging population. Recent research has highlighted the crucial role of glial cells, particularly astrocytes, in maintaining central nervous system homeostasis and their potential as therapeutic targets in neurodegenerative disorders. Various strategies are being explored to modulate astrocyte functions and develop astrocyte-specific delivery systems for potential cell therapy.
Review
Cardiac & Cardiovascular Systems
Mariem A. Sawan, Avery E. Calhoun, Yetunde A. Fatade, Nanette K. Wenger
Summary: Cardiac rehabilitation has proven benefits in reducing cardiovascular disease mortality, improving quality of life, and preventing readmissions in women. However, it is underutilized and barriers exist in referral, enrollment, and program completion.
PROGRESS IN CARDIOVASCULAR DISEASES
(2022)
Review
Chemistry, Inorganic & Nuclear
Boyang Wang, Haoqiang Song, Xiaoli Qu, Junbiao Chang, Bai Yang, Siyu Lu
Summary: Precise nanomedicine has been extensively explored for effective cancer imaging and treatment, with carbon dots being a new and highly interesting member of carbon-based nanomaterials in the field of nanomedicine. This review provides concise insights into the recent development of CDs in nanomedicine research, covering preparation, functionalization processes, and key applications.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Plant Sciences
Elizabeth A. Chapman, Hanne Cecilie Thomsen, Sophia Tulloch, Pedro M. P. Correia, Guangbin Luo, Javad Najafi, Lee R. DeHaan, Timothy E. Crews, Lennart Olsson, Per-Olof Lundquist, Anna Westerbergh, Pai Rosager Pedas, Soren Knudsen, Michael Palmgren
Summary: Perennial grain crops have the potential to be a valuable addition to sustainable agriculture as they require fewer inputs and improve soil health compared to annual crops. However, their low yields and early stages of domestication have hindered large-scale cultivation. To narrow the yield gap with annual crops, it is necessary to study the differences in life cycles, resource allocation, and reproductive strategies, as well as analyze the genetic and biochemical pathways controlling plant growth. This information can be used for tailored genetic improvement of perennial crops to enhance yield while maintaining the benefits of perennialism.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Forestry
Manuel Boissiere, Stibniati Atmadja, Manuel R. Guariguata, Habtemariam Kassa, Plinio Sist
Summary: In summary, there is a need for more attention to the socio-economic dimension of tree planting, particularly in fully considering the needs and participation of local communities. Risks identified include afforestation being misidentified as reforestation, lack of consideration for community participation and benefit sharing, and insufficient marketing for forest products.
FOREST ECOLOGY AND MANAGEMENT
(2021)
Article
Chemistry, Applied
Chen Wang, Junzhu Yang, Yuan Lu
Summary: Click chemistry is a rapid and reliable method for synthesizing a variety of molecules, emphasizing the development of new combinatorial chemistry methods based on the synthesis of carbon-heteroatomic bonds and the simple and efficient acquisition of molecular diversity through these reactions. Click chemistry methods are advancing towards precision, simplicity, and high returns, especially in producing polymer materials and some bright biomedical applications.
CHINESE JOURNAL OF CATALYSIS
(2023)
Article
Computer Science, Information Systems
Anders Karstensen, Troels Kolding, Claudio Rosa, Luis G. Uzeda Garcia, Klaus Pedersen, Navin Hathiramani
Summary: This paper investigates the challenges and opportunities of assigning spectrum for private 5G networks, specifically focusing on the 3.5 GHz band and regulation issued by the Danish spectrum authority Energistyrelsen. The study considers indoor and outdoor scenarios and proposes new solutions to enhance spectrum regulation options, protecting critical services and increasing network capacity in dense deployments.
Article
Oceanography
Peggy Schrobback, John Rolfe, Steven Rust, Sarah Ugalde
Summary: Assessing seafood supply chains is crucial for ensuring profitability, efficiency, and consumer satisfaction at both individual business and industry levels. Understanding the structure of the supply network and optimizing processes within the chain are key, but identifying broader challenges and opportunities at an industry level is also important for informing industry development strategies.
OCEAN & COASTAL MANAGEMENT
(2021)
Article
Chemistry, Multidisciplinary
Eloise Bevan, Jile Fu, Mauro Luberti, Ying Zheng
Summary: The latest research and development in hydrothermal carbonisation processes were reviewed to assess their feasibility for application in small towns in the UK. The study found that a hypothetical HTC plant could effectively process biodegradable municipal waste and sewage waste, providing renewable energy for small town residents. The evaluation highlighted opportunities and challenges associated with the application of HTC technology.
Article
Engineering, Civil
Antonio Bucchiarone, Sandro Battisti, Annapaola Marconi, Roberto Maldacea, Diego Cardona Ponce
Summary: Providing effective mobility services to residents and visitors is a complex socio-technical system task for city public managers. Smart mobility systems aim to support efficient transportation facilities and sustainable mobility while meeting the needs of people and businesses. The use of Autonomous Vehicles (AV) has become of interest for last-mile mobility services in cities, providing a possible solution for easier transportation with fewer vehicles.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2021)
Article
Computer Science, Information Systems
Suhyeon Lee, Seungjoo Kim
Summary: This paper explores the opportunities and limitations of blockchain in cyber defense and aims to reduce the gap in blockchain technology for cyber defense through research and analysis. The study finds that both research and government-led plans are actively promoting the application of blockchain, indicating its significant role in cyber defense.