Strategies for intranasal delivery of vaccines

ISCOMATRIX Adjuvant Induces Efficient Cross-Presentation of Tumor Antigen by Dendritic Cells via Rapid Cytosolic Antigen Delivery and Processing via Tripeptidyl Peptidase II

(2014) M. Schnurr et al.   JOURNAL OF IMMUNOLOGY

Novel vaccine development strategies for inducing mucosal immunity

(2012) Yoshiko Fukuyama et al.   Expert Review of Vaccines

Dendritic Cell Targeted Chitosan Nanoparticles for Nasal DNA Immunization against SARS CoV Nucleocapsid Protein

(2012) Dharmendra Raghuwanshi et al.   MOLECULAR PHARMACEUTICS

Immunological Evaluation of Lipopeptide Group A Streptococcus (GAS) Vaccine: Structure-Activity Relationship

(2012) Mehfuz Zaman et al.   PLoS One

Simple synthetic toll-like receptor 2 ligands

(2011) Abu-Baker M. Abdel-Aal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intranasal immunization with plasmid DNA encoding spike protein of SARS-coronavirus/polyethylenimine nanoparticles elicits antigen-specific humoral and cellular immune responses

(2011) Byoung-Shik Shim et al.   BMC IMMUNOLOGY

Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

(2011) S. Nierkens et al.   CANCER RESEARCH

Trans-10, cis-12-conjugated linoleic acid attenuates tumor necrosis factor-α production by lipopolysaccharide-stimulated porcine peripheral blood mononuclear cells through induction of interleukin-10

(2011) Keun-Hwa Kim et al.   CYTOKINE

A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine

(2011) Rolf J. Verheul et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Liposomal vaccine delivery systems

(2011) Malou Henriksen-Lacey et al.   Expert Opinion on Drug Delivery

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

(2011) Morgane Bomsel et al.   IMMUNITY

The Nasal Dendritic Cell-Targeting Flt3 Ligand as a Safe Adjuvant Elicits Effective Protection against Fatal Pneumococcal Pneumonia

(2011) Kosuke Kataoka et al.   INFECTION AND IMMUNITY

The mucosal and systemic immune responses elicited by a chitosan-adjuvanted intranasal influenza H5N1 vaccine

(2011) Signe C. Svindland et al.   Influenza and Other Respiratory Viruses

ISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cells In Vivo Leading to Effective Cross-Priming of CD8+ T Cells

(2011) P. Duewell et al.   JOURNAL OF IMMUNOLOGY

Chitosan Nanoparticles Act as an Adjuvant to Promote both Th1 and Th2 Immune Responses Induced by Ovalbumin in Mice

(2011) Zheng-Shun Wen et al.   Marine Drugs

Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity

(2011) F-E Johansen et al.   Mucosal Immunology

Virosome-Formulated Plasmodium falciparum AMA-1 & CSP Derived Peptides as Malaria Vaccine: Randomized Phase 1b Trial in Semi-Immune Adults & Children

(2011) Patrick Georges Cech et al.   PLoS One

Intranasal Delivery of Cationic PLGA Nano/Microparticles- Loaded FMDV DNA Vaccine Encoding IL-6 Elicited Protective Immunity against FMDV Challenge

(2011) Gang Wang et al.   PLoS One

Nasal immunization with plasmid DNA encoding P6 protein and immunostimulatory complexes elicits nontypeable Haemophilus influenzae-specific long-term mucosal immune responses in the nasopharynx

(2011) Satoru Kodama et al.   VACCINE

Intranasal delivery of Norwalk virus-like particles formulated in an in situ gelling, dry powder vaccine

(2011) Lissette S. Velasquez et al.   VACCINE

Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids

(2010) Noriko Ogasawara et al.   ACTA OTO-LARYNGOLOGICA

Structural requirement for the agonist activity of the TLR2 ligand Pam2Cys

(2010) Weiguang Zeng et al.   AMINO ACIDS

In vitro and in vivo evaluation of WGA–carbopol modified liposomes as carriers for oral peptide delivery

(2010) Abdallah Makhlof et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Liposomes as delivery systems for nasal vaccination: strategies and outcomes

(2010) Béatrice Heurtault et al.   Expert Opinion on Drug Delivery

Nasal vaccine innovation

(2010) Inderjit Jabbal-Gill   JOURNAL OF DRUG TARGETING

Design of Three-Component Vaccines against Group A Streptococcal Infections: Importance of Spatial Arrangement of Vaccine Components

(2010) Abu-Baker M. Abdel-Aal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Intranasal DNA Vaccination Induces Potent Mucosal and Systemic Immune Responses and Cross-protective Immunity Against Influenza Viruses

(2010) Lea Torrieri-Dramard et al.   MOLECULAR THERAPY

Effects of the TLR2 Agonists MALP-2 and Pam3Cys in Isolated Mouse Lungs

(2010) Martina Barrenschee et al.   PLoS One

Cross-protection against influenza virus infection by intranasal administration of M1-based vaccine with chitosan as an adjuvant

(2010) Zhiwei Sui et al.   VACCINE

Structure–activity relationship of lipopeptide Group A streptococcus (GAS) vaccine candidates on toll-like receptor 2

(2010) Mehfuz Zaman et al.   VACCINE

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: Nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen

(2010) Bram Slütter et al.   VACCINE

Achieving polio eradication: a review of health communication evidence and lessons learned in India and Pakistan

(2009) Rafael Obregón et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis

(2009) Sinead C. Corr et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Mucosal adjuvant activity of oligomannose-coated liposomes for nasal immunization

(2009) Mariko Ishii et al.   GLYCOCONJUGATE JOURNAL

Evaluation of ISCOM vaccines for mucosal immunization against hepatitis B

(2009) R. S. Pandey et al.   JOURNAL OF DRUG TARGETING

A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge

(2009) X Zhang et al.   Mucosal Immunology

Expression of maturation markers on murine dendritic cells in response to group A streptococcal lipopeptide vaccines

(2009) Michelle Yong et al.   VACCINE

The positive adjuvant effect of chitosan on antigen-specific cell-mediated immunity after chickens vaccination with live Newcastle disease vaccine

(2009) Fabienne Rauw et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Chitosan as an adjuvant for parenterally administered inactivated influenza vaccines

(2008) Y. Ghendon et al.   ARCHIVES OF VIROLOGY

The old Edward Jenner and the new public health: the future of vaccines in Europe

(2008) W. Ricciardi   EUROPEAN JOURNAL OF PUBLIC HEALTH

Chitosan formulations improve the immunogenicity of a GnRH-I peptide-based vaccine

(2008) Leonardo Sáenz et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Pharmaceutical Aspects of Intranasal Delivery of Vaccines Using Particulate Systems

(2008) Sameer Sharma et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Surface modified liposomes for nasal delivery of DNA vaccine

(2008) Kapil Khatri et al.   VACCINE

Spray-dried powders of starch and crosslinked poly(acrylic acid) as carriers for nasal delivery of inactivated influenza vaccine

(2008) D. Coucke et al.   VACCINE

Nasal Immunization Studies by Cationic, Fusogenic and Cationic-Fusogenic Liposomes Encapsulated with Tetanus Toxoid

(2008) M. Tafaghodi et al.   Current Drug Delivery

Calorimetric studies of the interaction between sodium alginate and sodium dodecyl sulfate in dilute solutions at different pH values

(2007) Jisheng Yang et al.   CARBOHYDRATE RESEARCH