期刊
ORGANIC CHEMISTRY FRONTIERS
卷 2, 期 2, 页码 114-118出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4qo00278d
关键词
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资金
- National Nature Science Foundation of China [21432009, 2127222, 91213303, 21172205]
A highly efficient and selective nitrogen source-promoted reaction for the synthesis of 2,4-disubstituted quinazolines from o-nitroacetophenones and alcohols catalyzed by Au/TiO2 has been developed via a hydrogen-transfer strategy. This reaction has good tolerance to air and water, a wide substrate scope, and represents a new avenue for practical multiple C N bond formation. More importantly, no additional additive, oxidant and reductant are required in the reaction and the catalyst can be recovered and reused readily.
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