Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells

(2015) Julie Helft et al.   IMMUNITY

Anti–PD-1 Therapy in Melanoma

(2015) Blanca Homet Moreno et al.   SEMINARS IN ONCOLOGY

Efficacy and safety of an intensified schedule of tremelimumab for chemotherapy-resistant malignant mesothelioma: an open-label, single-arm, phase 2 study

(2015) Luana Calabrò et al.   Lancet Respiratory Medicine

The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40

(2015) Andrea Khong et al.   BMC CANCER

Factors associated with survival in a large series of patients with malignant pleural mesothelioma in New South Wales

(2014) A Linton et al.   BRITISH JOURNAL OF CANCER

Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy

(2014) Alison M. McDonnell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Is cancer vaccination feasible at older age?

(2014) Claudia Gravekamp et al.   EXPERIMENTAL GERONTOLOGY

CTLA-4 and PD-1/PD-L1 Blockade: New Immunotherapeutic Modalities with Durable Clinical Benefit in Melanoma Patients

(2013) P. A. Ott et al.   CLINICAL CANCER RESEARCH

Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial

(2013) Luana Calabrò et al.   LANCET ONCOLOGY

Synergistic Effect of CTLA-4 Blockade and Cancer Chemotherapy in the Induction of Anti-Tumor Immunity

(2013) W. Joost Lesterhuis et al.   PLoS One

Major Cancer Regressions in Mesothelioma After Treatment with an Anti-Mesothelin Immunotoxin and Immune Suppression

(2013) R. Hassan et al.   Science Translational Medicine

Immunity and malignant mesothelioma: From mesothelial cell damage to tumor development and immune response-based therapies

(2012) Valerio Izzi et al.   CANCER LETTERS

IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase

(2012) Connie Jackaman et al.   INTERNATIONAL IMMUNOLOGY

The Use of Agonistic Anti-CD40 Therapy in Treatments for Cancer

(2012) Andrea Khong et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Inhibition of dendritic cell migration by transforming growth factor-β1 increases tumor-draining lymph node metastasis

(2012) Kazuhiro Imai et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Age-Related Oxidative Stress Compromises Endosomal Proteostasis

(2012) Elvira S. Cannizzo et al.   Cell Reports

Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway

(2010) Celine S. Lages et al.   AGING CELL

Pancreatic adenocarcinoma exerts systemic effects on the peripheral blood myeloid and plasmacytoid dendritic cells: an indicator of disease severity?

(2010) Vegard Tjomsland et al.   BMC CANCER

High Blood Neutrophil-to-Lymphocyte Ratio Is an Indicator of Poor Prognosis in Malignant Mesothelioma Patients Undergoing Systemic Therapy

(2010) S. C. H. Kao et al.   CLINICAL CANCER RESEARCH

CD40-activated B cells contribute to mesothelioma tumor regression

(2010) Connie Jackaman et al.   IMMUNOLOGY AND CELL BIOLOGY

Therapeutic efficacy of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with metastatic melanoma unresponsive to prior systemic treatments: clinical and immunological evidence from three patient cases

(2009) Anna Maria Di Giacomo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb

(2009) Oihana Murillo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells

(2009) C. Jackaman et al.   EUROPEAN RESPIRATORY JOURNAL

Locally Administered TLR7 Agonists Drive Systemic Antitumor Immune Responses That Are Enhanced by Anti-CD40 Immunotherapy

(2009) S. A. Broomfield et al.   JOURNAL OF IMMUNOLOGY

Therapeutic influence on circulating and monocyte-derived dendritic cells in laryngeal squamous cell carcinoma patients

(2008) Xiao Jie Ma et al.   ACTA OTO-LARYNGOLOGICA

CD1a expression defines an interleukin-12 producing population of human dendritic cells

(2008) M. Cernadas et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Sunitinib-Induced Myeloid Lineage Redistribution in Renal Cell Cancer Patients: CD1c+ Dendritic Cell Frequency Predicts Progression-Free Survival

(2008) H. van Cruijsen et al.   CLINICAL CANCER RESEARCH

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site

(2008) Connie Jackaman et al.   INTERNATIONAL IMMUNOLOGY

Enumeration of blood dendritic cells in patients with multiple myeloma at presentation and through therapy

(2008) Simon J. Harrison et al.   LEUKEMIA & LYMPHOMA

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

(2008) Scott H Robbins et al.   GENOME BIOLOGY