Novel cytokine signaling pathways in inflammatory bowel disease: insight into the dichotomous functions of IL-33 during chronic intestinal inflammation

IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes

(2014) N. E. Humphreys et al.   JOURNAL OF IMMUNOLOGY

IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4

(2014) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

(2010) W. A. Verri et al.   ANNALS OF THE RHEUMATIC DISEASES

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Over-expression of IL-33 leads to spontaneous pulmonary inflammation in mIL-33 transgenic mice

(2010) Xiang Zhiguang et al.   IMMUNOLOGY LETTERS

Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis

(2010) Saori Matsuba-Kitamura et al.   INTERNATIONAL IMMUNOLOGY

Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis

(2010) Ayako Kobori et al.   JOURNAL OF GASTROENTEROLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-33 is a crucial amplifier of innate rather than acquired immunity

(2010) K. Oboki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

(2010) Luca Pastorelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis

(2009) Gaby Palmer et al.   ARTHRITIS AND RHEUMATISM

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes

(2009) I. Stuart Wood et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma

(2009) Xiaojin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected withToxoplasma gondii

(2009) Leigh A. Jones et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

The interleukin-23 axis in intestinal inflammation

(2009) Philip P. Ahern et al.   IMMUNOLOGICAL REVIEWS

IL-33 is upregulated in colonocytes of ulcerative colitis

(2009) Jakob Benedict Seidelin et al.   IMMUNOLOGY LETTERS

Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease

(2009) Caroll J. Beltrán et al.   INFLAMMATORY BOWEL DISEASES

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation

(2009) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

The Essential Role of Single Ig IL-1 Receptor-Related Molecule/Toll IL-1R8 in Regulation of Th2 Immune Response

(2009) K. Bulek et al.   JOURNAL OF IMMUNOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Interleukin-1β and the Autoinflammatory Diseases

(2009) Charles A. Dinarello   NEW ENGLAND JOURNAL OF MEDICINE

The cytokine interleukin-33 mediates anaphylactic shock

(2009) P. N. Pushparaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

(2009) Jiri F. P. Wagenaar et al.   PLoS Neglected Tropical Diseases

Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation

(2008) Axel M. Küchler et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections

(2008) Reece G Marillier et al.   BMC IMMUNOLOGY

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33

(2008) Gaby Palmer et al.   CYTOKINE

Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21

(2008) Daniele Fina et al.   GASTROENTEROLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

IL-33 reduces the development of atherosclerosis

(2008) Ashley M. Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease

(2008) J Wehkamp et al.   Mucosal Immunology

IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut

(2008) M Pasparakis   Mucosal Immunology

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA