Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth

Targeting the PI3K/Akt/mTOR pathway in castration-resistant prostate cancer

(2013) Rhonda L Bitting et al.   ENDOCRINE-RELATED CANCER

Metabolomic Profiling Identifies Biochemical Pathways Associated with Castration-Resistant Prostate Cancer

(2013) Akash K. Kaushik et al.   JOURNAL OF PROTEOME RESEARCH

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

(2013) Wenjing Du et al.   NATURE CELL BIOLOGY

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation

(2012) Nahyun Choi et al.   CANCER CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence

(2012) Vikas P. Sukhatme et al.   FEBS LETTERS

Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells

(2012) Suresh Veeramani et al.   FREE RADICAL BIOLOGY AND MEDICINE

The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate

(2012) Chiara Riganti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pyruvate kinase type M2 is upregulated in colorectal cancer and promotes proliferation and migration of colon cancer cells

(2012) Cheng-Fu Zhou et al.   IUBMB LIFE

Glucose-6-phosphate dehydrogenase, NADPH, and cell survival

(2012) Robert C. Stanton   IUBMB LIFE

Androgens Promote Prostate Cancer Cell Growth through Induction of Autophagy

(2012) Yan Shi et al.   MOLECULAR ENDOCRINOLOGY

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism

(2012) W. Yi et al.   SCIENCE

Targeting CreERT2 expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis

(2012) Li Zhang et al.   TRANSGENIC RESEARCH

Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

(2012) Barbara Chaneton et al.   TRENDS IN BIOCHEMICAL SCIENCES

PTEN in cancer, metabolism, and aging

(2012) Ana Ortega-Molina et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival

(2012) Susana Ros et al.   Cancer Discovery

Identification of transaldolase as a novel serum biomarker for hepatocellular carcinoma metastasis using xenografted mouse model and clinic samples

(2011) Cun Wang et al.   CANCER LETTERS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells

(2011) Nana-Maria Grüning et al.   Cell Metabolism

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells

(2011) W.-C. Huang et al.   MOLECULAR CANCER RESEARCH

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

(2011) Peng Jiang et al.   NATURE CELL BIOLOGY

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

(2011) D. Anastasiou et al.   SCIENCE

Overexpression of G6PD is associated with poor clinical outcome in gastric cancer

(2011) Jixu Wang et al.   TUMOR BIOLOGY

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

CaM Kinase Kinase β-Mediated Activation of the Growth Regulatory Kinase AMPK Is Required for Androgen-Dependent Migration of Prostate Cancer Cells

(2010) Daniel E. Frigo et al.   CANCER RESEARCH

Glucose Metabolism via the Pentose Phosphate Pathway Relative to Nucleic Acid and Protein Synthesis in the Human Placenta

(2010) Peter Beaconsfield et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways

(2010) Lin   INTERNATIONAL JOURNAL OF ONCOLOGY

Endogenous Control Genes in Prostate Cells: Evaluation of Gene Expression Using ‘Real-Time’ Quantitative Polymerase Chain Reaction

(2010) Emmanuel Nna et al.   MEDICAL PRINCIPLES AND PRACTICE

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Renal cell carcinoma and oxidative stress: The lack of peroxisomes

(2009) Wilma M. Frederiks et al.   ACTA HISTOCHEMICA

A New G6PD Knockdown Tumor-Cell Line with Reduced Proliferation and Increased Susceptibility to Oxidative Stress

(2009) Danyi Li et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Castration-Resistant Prostate Cancer: Locking Up the Molecular Escape Routes

(2009) R. M. Attar et al.   CLINICAL CANCER RESEARCH

Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway

(2009) Todd Morgan et al.   CURRENT CANCER DRUG TARGETS

PTENgenomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer

(2009) Kanishka Sircar et al.   JOURNAL OF PATHOLOGY

Mammalian target of rapamycin: A new target in prostate cancer

(2009) Jaskarn S. Rai et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance

(2008) S. M. Dehm et al.   CANCER RESEARCH

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation

(2008) D. E. Frigo et al.   MOLECULAR CANCER THERAPEUTICS