Frequent MYC coamplification and DNA hypomethylation of multiple genes on 8q in 8p11-p12-amplified breast carcinomas

PPAPDC1B and WHSC1L1 Are Common Drivers of the 8p11-12 Amplicon, Not Only in Breast Tumors But Also in Pancreatic Adenocarcinomas and Lung Tumors

(2013) Sardar F. Mahmood et al.   AMERICAN JOURNAL OF PATHOLOGY

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

(2013) Eeva M. Sommer et al.   BIOCHEMICAL JOURNAL

Histone Deacetylase Regulation of ATM-Mediated DNA Damage Signaling

(2013) K. T. Thurn et al.   MOLECULAR CANCER THERAPEUTICS

Luminal Breast Cancer Cell Lines Overexpressing ZNF703 Are Resistant to Tamoxifen through Activation of Akt/mTOR Signaling

(2013) Xi Zhang et al.   PLoS One

Structural bioinformatics of the general transcription factor TFIID

(2012) Maja Malkowska et al.   BIOCHIMIE

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

(2012) D. Wang et al.   BIOINFORMATICS

Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes

(2012) Ina Schulte et al.   BMC GENOMICS

Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models

(2012) Yesim Gökmen-Polar et al.   BREAST CANCER RESEARCH AND TREATMENT

A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines

(2012) Craig Carson et al.   Pigment Cell & Melanoma Research

RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence

(2012) Mei-Ling Kuo et al.   Scientific Reports

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

(2011) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

ZNF703is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

(2011) Daniel G. Holland et al.   EMBO Molecular Medicine

ZNF703gene amplification at 8p12 specifies luminal B breast cancer

(2011) Fabrice Sircoulomb et al.   EMBO Molecular Medicine

Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability

(2011) Chang Hyeok An et al.   HUMAN PATHOLOGY

N-myc Downstream-regulated Gene 1 (NDRG1) a Differentiation Marker of Human Breast Cancer

(2011) Abbas Fotovati et al.   PATHOLOGY & ONCOLOGY RESEARCH

Increased N-myc downstream-regulated gene 1 expression is associated with breast atypia-to-carcinoma progression

(2011) Xiao-Yun Mao et al.   TUMOR BIOLOGY

Identification of fusion genes in breast cancer by paired-end RNA-sequencing

(2011) Henrik Edgren et al.   GENOME BIOLOGY

Expression and Relevance of TRPS-1: A New GATA Transcription Factor in Breast Cancer

(2011) Jie Qing Chen et al.   Hormones & Cancer

Genome profiling of ERBB2-amplified breast cancers

(2010) Fabrice Sircoulomb et al.   BMC CANCER

Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients

(2010) Maria Aparecida Nagai et al.   BREAST CANCER RESEARCH AND TREATMENT

High-resolution genomic profiling to predict 10-year overall survival in node-negative breast cancer

(2010) Elin Möllerström et al.   CANCER GENETICS AND CYTOGENETICS

Transforming Properties of 8p11-12 Amplified Genes in Human Breast Cancer

(2010) Z.-Q. Yang et al.   CANCER RESEARCH

FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

(2010) N. Turner et al.   CANCER RESEARCH

Clinical Implications of Gene Dosage and Gene Expression Patterns in Diploid Breast Carcinoma

(2010) T. Z. Parris et al.   CLINICAL CANCER RESEARCH

Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis

(2009) Mirjam C. Boelens et al.   LUNG CANCER

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

(2009) S S Kwek et al.   ONCOGENE

Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease

(2008) M W Helms et al.   BRITISH JOURNAL OF CANCER

Characterization of the Recurrent 8p11-12 Amplicon Identifies PPAPDC1B, a Phosphatase Protein, as a New Therapeutic Target in Breast Cancer

(2008) I. Bernard-Pierrot et al.   CANCER RESEARCH

Cancer Epigenetics: Modifications, Screening, and Therapy

(2007) Gal-Yam Einav Nili et al.   Annual Review of Medicine