Article
Chemistry, Analytical
Amandeep Kaur, Sanjoli Sharma, Shilpa Rana, Rishika Rohilla, Nirmal Prabhakar
Summary: In this study, an impedimetric immunosensor based on Ag-CuO@PANI nanocomposite was developed for sensitive detection of MUC1. The immunosensor showed excellent analytical performance, reproducibility, and long-term storage stability under refrigeration conditions.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Elif Burcu Aydin, Muhammet Aydin, Mustafa Kemal Sezginturk
Summary: An innovative biosensing design strategy was utilized to develop a label-free immunosensor for accurate detection of the potential biomarker calreticulin (CRT) in breast carcinoma. The immunosensor showed a wide detection range, low detection limit, and high recovery rate, with good repeatability and reproducibility.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Ashutosh Kumar, Tamal Sarkar, Pratima R. Solanki
Summary: In this study, gadolinium oxide nanoparticles (Gd2O3 NPs) were synthesized and functionalized to create a highly efficient immunosensor for the detection of Vibrio cholera toxin (CT). The Gd2O3 NPs were produced using microwave irradiation and characterized using various techniques. The NPs were then functionalized with APTES and deposited onto an ITO-coated glass substrate. The immunosensor demonstrated excellent electrochemical reaction against CT, with a high sensitivity and low detection limit.
Article
Chemistry, Analytical
Shalini Nagabooshanam, Bhusankar Talluri, Tiju Thomas, Satheesh Krishnamurthy, Ashish Mathur
Summary: An ultra-sensitive immunosensing platform using digestive-ripened copper oxide quantum dots grafted on a gold microelectrode was developed for the impedimetric detection of parathion. The platform showed a wide linear range of detection and low limit of detection, along with stability and selectivity.
Article
Chemistry, Multidisciplinary
Noorah A. Faqihi, Mahmood M. S. Abdullah, Mohd Sajid Ali, Hamad A. Al-Lohedan, Zainab M. Almarhoon
Summary: Recently, magnetite nanoparticles (MNPs) have been highly valued for their unique properties and potential in oil spill cleanup. In this study, the surface of MNPs was functionalized using newly synthesized hydrophobic ionic liquids (ILs) and applied for oil spill cleanup. The functionalized MNPs showed high oil removal efficiency even at low MNP ratios. Additionally, MNPs functionalized with GEOA-IL exhibited higher oil removal efficiency compared to those functionalized with GEDA-IL. Furthermore, the functionalized MNPs showed excellent reusability over multiple cycles.
JOURNAL OF CHEMISTRY
(2023)
Article
Biophysics
Oluwafemi S. Obisesan, Timothy O. Ajiboye, Sabelo D. Mhlanga, Hazel T. Mufhandu
Summary: Magnetic nanoparticles (MNPs) have become a focus of attention in the past decade due to their unique properties, making them suitable for drug delivery and various biomedical applications when combined with biodegradable polymers. This review discusses the synthesis of polycaprolactones (PCL), methods of synthesizing magnetic iron oxide nanoparticles, and the synthesis of PCL-based composites. It comprehensively reviews the application of these composites in drug delivery, cancer treatment, wound healing, hyperthermia, bone tissue engineering, and other biomedical applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Boyang Chen, Janice Kiely, Ibidapo Williams, Richard Luxton
Summary: Lower yields and poorer quality of biopharmaceutical products are caused by cell death in bioreactors, which is often associated with apoptosis. A novel impedance spectroscopy measurement technique using zinc oxide and copper oxide was developed for the detection of total caspase-9 in complex fluids. The biosensor demonstrated enhanced sensitivity and a detection limit of 0.07 U/mL in buffer, making it a potential screening device for apoptosis monitoring.
BIOELECTROCHEMISTRY
(2023)
Article
Chemistry, Physical
Lichuang Zhang, Hao Xu, Ziyi Cheng, Yan Wei, Ruize Sun, Ziwei Liang, Yinchun Hu, Liqin Zhao, Xiaojie Lian, Xia Li, Di Huang
Summary: The surface modification of nanoparticles with cellular protein components improved the targeting performance of nanoparticles, showing potential for clinical targeted diagnosis and treatment of cancer.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Review
Chemistry, Inorganic & Nuclear
Anees A. Ansari, Vijay K. Thakur, Guanying Chen
Summary: Functionalized upconversion nanoparticles have shown significant success in bio-photonic applications, offering unique luminescent properties and high emission efficiency. With advantages such as good color purity and easy surface functionalization, they are promising materials for biomedical and clinical sciences, particularly in biosensing applications. Ongoing efforts focus on enhancing emission efficiency and exploring new functionalization techniques to further advance their application potential.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Hadeel Saad, F. A. Nour El-Dien, Nadia E. A. El-Gamel, Ahmed S. Abo Dena
Summary: Water contamination is a serious global issue due to the depletion of water resources suitable for drinking and agriculture. Researchers have developed a magnetic adsorbent nanomaterial for removing the anionic dye bromocresol green from wastewater. The adsorbent has high adsorption capacity and can be easily removed using a strong magnetic field.
Article
Chemistry, Analytical
Xiao Wang, Xiaochen Liao, Lisha Mei, Mengmeng Zhang, Siyu Chen, Xiuwen Qiao, Chenglin Hong
Summary: In this study, a dual-mode sensor combining the high sensitivity of electrochemical analysis with the simplicity and rapidity of colorimetric analysis was successfully developed for accurate and quick detection of CEA. The sensor showed excellent detection performance with a wide detection range and low detection limits, providing a new detection method for early cancer detection and prognosis monitoring.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Engineering, Electrical & Electronic
Syazana Ameera Syed Amri, Nor Azah Yusof, Jaafar Abdullah, Siti Fatimah Abd Rahman, Umi Zulaikha Mohd Azmi
Summary: A new electrochemical immunosensor based on Fe3O4-Au NC was developed for sensitive detection of M. tuberculosis. The sensor showed sensitive detection in the range of 0-9.0 μg/mL with a detection limit of 1.32 ng/mL, offering a promising platform for future diagnostic studies on various mycobacterium pathogens.
IEEE SENSORS JOURNAL
(2021)
Article
Chemistry, Analytical
Chenhong Yu, Li Li, Yaping Ding, Huajie Liu, Hanyue Cui
Summary: This paper introduces a novel electrochemical aptasensor for trace analysis of cortisol, which integrates molecular imprinting techniques. The sensor, based on functionalized graphene and nitrogen-doped carbon quantum dots, exhibits linearity and a low detection limit. Moreover, it can determine cortisol in salivary samples with high recovery values.
Article
Multidisciplinary Sciences
Andreina Chiu-Lam, Edward Staples, Carl J. Pepine, Carlos Rinaldi
Summary: The study reports on an mCPA containing superparamagnetic iron oxide nanoparticles that can increase the preservation time of cryopreserved organs through nanowarming, reduce damage caused by slow rewarming, and have low cytotoxicity. The results demonstrate that this formulated mCPA is suitable for perfusion, vitrification, and nanowarming of whole organs.
