Role of sinoatrial node architecture in maintaining a balanced source-sink relationship and synchronous cardiac pacemaking

Upregulation of Adenosine A1 Receptors Facilitates Sinoatrial Node Dysfunction in Chronic Canine Heart Failure by Exacerbating Nodal Conduction Abnormalities Revealed by Novel Dual-Sided Intramural Optical Mapping

(2014) Qing Lou et al.   CIRCULATION

Gene Therapy and Biological Pacing

(2014) Michael R. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Cycle Length Restitution in Sinoatrial Node Cells: A Theory for Understanding Spontaneous Action Potential Dynamics

(2014) Patric Glynn et al.   PLoS One

Importance of Gradients in Membrane Properties and Electrical Coupling in Sinoatrial Node Pacing

(2014) Shin Inada et al.   PLoS One

Improving cardiac rhythm with a biological pacemaker

(2014) N. V. Munshi et al.   SCIENCE

Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block

(2014) Y.-F. Hu et al.   Science Translational Medicine

Role of the intercalated disc in cardiac propagation and arrhythmogenesis

(2014) Andre G. Kleber et al.   Frontiers in Physiology

Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis

(2013) Roseanne M. Wolf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diabetes increases mortality after myocardial infarction by oxidizing CaMKII

(2013) Min Luo et al.   JOURNAL OF CLINICAL INVESTIGATION

HCN2/SkM1 Gene Transfer Into Canine Left Bundle Branch Induces Stable, Autonomically Responsive Biological Pacing at Physiological Heart Rates

(2013) Gerard J.J. Boink et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Conduction barriers and pathways of the sinoatrial pacemaker complex: their role in normal rhythm and atrial arrhythmias

(2012) Vadim V. Fedorov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ca 2+ -Stimulated Adenylyl Cyclase AC1 Generates Efficient Biological Pacing as Single Gene Therapy and in Combination With HCN2

(2012) Gerard J.J. Boink et al.   CIRCULATION

Structure–Function Relationship in the Sinus and Atrioventricular Nodes

(2012) T. Nikolaidou et al.   PEDIATRIC CARDIOLOGY

Implantation of Sinoatrial Node Cells Into Canine Right Ventricle: Biological Pacing Appears Limited by the Substrate

(2011) Hao Zhang et al.   CELL TRANSPLANTATION

Oxidized CaMKII causes cardiac sinus node dysfunction in mice

(2011) Paari Dominic Swaminathan et al.   JOURNAL OF CLINICAL INVESTIGATION

The road to biological pacing

(2011) Michael R. Rosen et al.   Nature Reviews Cardiology

An Intuitive Safety Factor for Cardiac Propagation

(2010) Patrick M. Boyle et al.   BIOPHYSICAL JOURNAL

Mechanistic Links Between Na + Channel (SCN5A) Mutations and Impaired Cardiac Pacemaking in Sick Sinus Syndrome

(2010) Timothy D. Butters et al.   CIRCULATION RESEARCH

Biological Therapies for Cardiac Arrhythmias

(2010) Hee Cheol Cho et al.   CIRCULATION RESEARCH

A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

(2010) Edward G. Lakatta et al.   CIRCULATION RESEARCH

Optical Mapping of the Isolated Coronary-Perfused Human Sinus Node

(2010) Vadim V. Fedorov et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Determinants of Heterogeneity, Excitation and Conduction in the Sinoatrial Node: A Model Study

(2010) Ronit V. Oren et al.   PLoS Computational Biology

Structural and Functional Evidence for Discrete Exit Pathways That Connect the Canine Sinoatrial Node and Atria

(2009) Vadim V. Fedorov et al.   CIRCULATION RESEARCH

‘And the beat goes on’ The cardiac conduction system: the wiring system of the heart

(2009) Mark R. Boyett   EXPERIMENTAL PHYSIOLOGY

Genesis and Regulation of the Heart Automaticity

(2008) Matteo E. Mangoni et al.   PHYSIOLOGICAL REVIEWS