High-fat diet-induced changes in liver thioredoxin and thioredoxin reductase as a novel feature of insulin resistance

The Rare TXNRD1_v3 (“v3”) Splice Variant of Human Thioredoxin Reductase 1 Protein Is Targeted to Membrane Rafts byN-Acylation and Induces Filopodia Independently of Its Redox Active Site Integrity

(2013) Marcus Cebula et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivomulti-tissue efficacy of peroxisome proliferator-activated receptor-γtherapy on glucose and fatty acid metabolism in obese type 2 diabetic rats

(2013) Samuel Nemanich et al.   Obesity

Redox Cycling of 1,2-Naphthoquinone by Thioredoxin1 through Cys32 and Cys35 Causes Inhibition of Its Catalytic Activity and Activation of ASK1/p38 Signaling

(2012) Yasuhiro Shinkai et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

The role of thioredoxin in the regulation of cellular processes by S-nitrosylation

(2011) Rajib Sengupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Increased AdipocyteS-Nitrosylation Targets Anti-lipolytic Action of Insulin

(2011) Hilla Ovadia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Signaling and Insulin Sensitizing in Muscle and Liver of Obese Monkeys: Peroxisome Proliferator-Activated Receptor Gamma Agonist Improves Defective Activation of Atypical Protein Kinase C

(2010) Heidi K. Ortmeyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity

(2010) Yunfei Wu et al.   ATHEROSCLEROSIS

Insulin Resistance in Nonalcoholic Fatty Liver Disease

(2010) E. Bugianesi et al.   CURRENT PHARMACEUTICAL DESIGN

Oxidative stress and the etiology of insulin resistance and type 2 diabetes

(2010) Erik J. Henriksen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of a high-fat diet on energy metabolism and ROS production in rat liver

(2010) Guillaume Vial et al.   JOURNAL OF HEPATOLOGY

Inhibition of Protein Tyrosine Phosphatase-1B with Antisense Oligonucleotides Improves Insulin Sensitivity and Increases Adiponectin Concentrations in Monkeys

(2009) Michael M. Swarbrick et al.   ENDOCRINOLOGY

PI-3 K/AKT and ERK signaling pathways mediate leptin-induced inhibition of PPARγ gene expression in primary rat hepatic stellate cells

(2009) Yajun Zhou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CysteineS-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation

(2008) Yi-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulation of Protein Tyrosine Phosphatase 1B by Manipulation of Dietary Selenium Affects the Triglyceride Concentration in Rat Liver

(2008) Andreas S. Mueller et al.   JOURNAL OF NUTRITION

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

(2008) Naoto Matsuzawa-Nagata et al.   METABOLISM-CLINICAL AND EXPERIMENTAL