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Drug Burden Index in older adults: theoretical and practical issues

CLINICAL INTERVENTIONS IN AGING (2014)

期刊

CLINICAL INTERVENTIONS IN AGING

卷 9, 期 -, 页码 1503-1515

出版社

DOVE MEDICAL PRESS LTD

DOI: 10.2147/CIA.S66660

关键词

Drug Burden Index; anticholinergics; sedative medications; high-risk prescribing; older adults; pharmacological risk assessment tools; deprescribing

类别

Geriatrics & Gerontology

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Reagent

摘要

Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.

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