NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain-of-Function Variant Decreases the Risk of Renal Underexcretion Gout

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

(2014) Akiyoshi Nakayama et al.   Scientific Reports

A common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility

(2013) Akiyoshi Nakayama et al.   Human Cell

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

(2013) Hirotaka Matsuo et al.   Scientific Reports

The renal urate transporter SLC17A1 locus: confirmation of association with gout

(2012) Jade E Hollis-Moffatt et al.   ARTHRITIS RESEARCH & THERAPY

Decreased extra-renal urate excretion is a common cause of hyperuricemia

(2012) Kimiyoshi Ichida et al.   Nature Communications

Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2)

(2011) Y. Kawamura et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

A proposal for identifying the low renal uric acid clearance phenotype

(2011) Praveen L Indraratna et al.   ARTHRITIS RESEARCH & THERAPY

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors

(2010) Qiong Yang et al.   Circulation-Cardiovascular Genetics

Type 1 Sodium-dependent Phosphate Transporter (SLC17A1 Protein) Is a Cl−-dependent Urate Exporter

(2010) Masafumi Iharada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout

(2009) W. Urano et al.   ANNALS OF THE RHEUMATIC DISEASES

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia

(2009) D. Dinour et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease

(2009) Klaus Stark et al.   PLoS One

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

(2009) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

(2009) H. Matsuo et al.   Science Translational Medicine

Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia

(2008) Hirotaka Matsuo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Uric Acid and Cardiovascular Risk

(2008) Daniel I. Feig et al.   NEW ENGLAND JOURNAL OF MEDICINE