期刊
NANOSCALE RESEARCH LETTERS
卷 8, 期 -, 页码 -出版社
SPRINGER
DOI: 10.1186/1556-276X-8-502
关键词
Nanoelectrode; Silicon nanowire; Biomolecule sensing; Cyclic voltammograms; High current density
资金
- National Research Foundation of Korea (NRF)
- Korea government (MEST) [2012R1A2A1A03010558, 2012R1A1A2006453, 2012-0000888]
- Pioneer Research Program for Converging Technology through the Korea Science and Engineering Foundation [2009-008-1529]
- Ministry of Education, Science Technology
- Seoul RBD program [ST110029]
- National Research Foundation of Korea [2012R1A2A1A03010558, 2012R1A1A2006453] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Au-coated vertical silicon nanowire electrode array (VSNEA) was fabricated using a combination of bottom-up and top-down approaches by chemical vapor deposition and complementary metal-oxide-semiconductor process for biomolecule sensing. To verify the feasibility for the detection of biomolecules, Au-coated VSNEA was functionalized using peptides having a fluorescent probe. Cyclic voltammograms of the peptide-functionalized Au-coated VSNEA show a steady-state electrochemical current behavior. Because of the critically small dimension and vertically aligned nature of VSNEA, the current density of Au-coated VSNEA was dramatically higher than that of Au film electrodes. Au-coated VSNEA further showed a large current difference with and without peptides that was nine times more than that of Au film electrodes. These results indicate that Au-coated VSENA is highly effective device to detect peptides compared to conventional thin-film electrodes. Au-coated VSNEA can also be used as a divergent biosensor platform in many applications.
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