Article
Psychology, Developmental
Elise Marriott, James Stacey, Olivia Mary Hewitt, Nienke E. Verkuijl
Summary: This study is the first to investigate the experiences of parents of autistic children who have significant autistic traits themselves. The findings suggest that these parents face difficulties with parental mental health and navigating professional services, while the interaction between parental and child autistic traits plays a significant role in parenting. The study highlights the need for adequately funded, tailored, and accessible services for these families.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Multidisciplinary Sciences
Yuka Shiota, Tetsu Hirosawa, Yuko Yoshimura, Sanae Tanaka, Chiaki Hasegawa, Sumie Iwasaki, Kyung-Min An, Daiki Soma, Masuhiko Sano, Shigeru Yokoyama, Mitsuru Kikuchi
Summary: Sub-threshold autistic traits are common in the general population, with the CNTNAP2 gene associated with the development of ASD. Children with the rs2710102 A-allele exhibit differences in social interaction and intelligence compared to GG homozygotes in the typically developing group.
Article
Clinical Neurology
Richard H. Cole, Michael S. Elmalem, Panayiota Petrochilos
Summary: In a cohort of adults with Functional Neurological Disorder (FND), the prevalence of autistic traits and alexithymia is reported, along with the associated psychiatric comorbidity. Furthermore, it is explored whether alexithymia mediates the association between autistic traits and comorbidity.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Neurosciences
Azadeh Kushki, Robyn E. Cardy, Sina Panahandeh, Mahan Malihi, Christopher Hammill, Jessica Brian, Alana Iaboni, Margot J. Taylor, Russell Schachar, Jennifer Crosbie, Paul Arnold, Elizabeth Kelley, Muhammad Ayub, Robert Nicolson, Stelios Georgiades, Jason P. Lerch, Evdokia Anagnostou
Summary: The study discovered associations between social communication abilities and distributed cortical and subcortical networks implicated in social behaviors, language, attention, memory, and executive functions, as well as three data-driven, diagnosis-agnostic subgroups based on the patterns of association in these networks.
Article
Environmental Sciences
Johanna Inhyang Kim, Jung Lee, Kyung-Shin Lee, Young Ah Lee, Choong Ho Shin, Yun-Chul Hong, Bung-Nyun Kim, Youn-Hee Lim
Summary: This study found that exposure to certain phthalate metabolites during pregnancy can lead to increased autistic traits in young children, while exposure to other metabolites during early childhood may result in autistic traits in older school-aged children, especially boys.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Psychiatry
Hiroshi Komatsu, Takashi Ono, Yuji Onouchi, Goh Onoguchi, Yoshinori Maita, Yusuke Ishida, Takahiro Maki, Akiko Oba, Hiroaki Tomita, Yoshihisa Kakuto
Summary: This study investigated the association between polydipsia and autistic traits in patients with schizophrenia spectrum disorders (SSDs). The results showed that patients with polydipsia had higher scores on autistic traits, and male gender and autistic traits were significant predictors of polydipsia.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Clinical
Anton P. Martinez, Sophie Wickham, Georgina Rowse, Elizabeth Milne, Richard P. Bentall
Summary: Studies have shown significant associations between autistic traits and probable psychosis, paranoia, thought insertion, and strange experiences in both the APMS 2007 and APMS 2014 datasets. Additionally, a significant association was found between autistic traits and hallucinations.Participants in the highest quartile of autistic traits had increased risk of probable psychosis with odds ratios of 15.5 in 2007 and 22.5 in 2014.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychiatry
Yvonne Schroeder, Daniela Michelle Hohmann, Tina Meller, Ulrika Evermann, Julia-Katharina Pfarr, Andreas Jansen, Inge Kamp-Becker, Sarah Grezellschak, Igor Nenadic
Summary: Individuals with higher levels of autism-spectrum-like features show decreased white matter integrity and increased cortical volume, which resemble regional brain structure alterations found in individuals with ASD.
EUROPEAN PSYCHIATRY
(2021)
Article
Genetics & Heredity
Helen O'Reilly, Yanyan Ni, Samantha Johnson, Dieter Wolke, Neil Marlow
Summary: The study found that young adults born extremely preterm (EP) scored significantly higher on autism traits and had lower scores in emotion recognition and empathy compared to term-born controls. A larger proportion of EP survivors have subclinical difficulties associated with autism than confirmed diagnoses, with a moderate correlation between childhood autism symptom scores and autistic traits in young adulthood.
Article
Multidisciplinary Sciences
Agustina Birba, Joana Lopez-Pigui, Inmaculada Leon Santana, Adolfo M. Garcia
Summary: This study examined the differences in comprehension of social and non-social concepts in individuals with autistic-like traits and typically developing individuals. The results showed selective deficits in understanding text-level social concepts among those with autistic-like traits, while there were no significant differences in non-social concept comprehension. These findings provide empirical constraints for situated models of social semantics.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Qingmin Kong, Peijun Tian, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen
Summary: Research on gut microbiota in autism has predominantly focused on children, with limited understanding of the dynamic changes from weaning to adulthood. This study tracked autistic-like rats induced by VPA from weaning to sexual maturation, revealing significant developmental disorders and differences in gut microbiota between autistic-like and healthy rats. While the microbiota and SCFAs related to autism were influenced by age and diet, some correlations remained consistent regardless of these factors, suggesting their potential role in the development of autistic-like behaviors.
Article
Medicine, General & Internal
Jacopo Pruccoli, Simone Rosa, Carlo Alberto Cesaroni, Elisabetta Malaspina, Antonia Parmeggiani
Summary: The study found that Autism Spectrum Disorder (ASD) traits do not impact the treatment intensity and outcomes of adolescent patients with Anorexia Nervosa (AN). Patients with AN and suspected ASD traits showed overlapping treatment types, psychopathological, and weight outcomes compared to other AN patients. ASD total scores were not correlated with treatment intensity or outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychiatry
Yanting Li, Zilong Wei, Min Shao, Mingyu Hong, Di Yang, Longli Luo, Jing Meng
Summary: Previous studies have shown that individuals with autistic traits may have impaired empathic responses when observing others' pain in static stimuli. This study investigated whether individuals with autistic traits also exhibit impaired empathy for pain in response to dynamic stimuli.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Clinical
Aimilia Kallitsounaki, David M. Williams
Summary: This study investigates the link between autism spectrum disorder (ASD) and gender diversity, finding that ASD affects gender cognition in autistic cisgender individuals and reveals sex differences among this group. Autistic cisgender individuals also report more gender dysphoric feelings and less gender-typed behavior from childhood compared to their non-autistic counterparts. Both non-autistic transgender and autistic transgender individuals show more ASD-like traits than non-autistic cisgender individuals, with the latter group also experiencing mentalizing difficulties.
ARCHIVES OF SEXUAL BEHAVIOR
(2022)
Article
Psychiatry
Fumiyo Oshima, William Mandy, Mikuko Seto, Minako Hongo, Aki Tsuchiyagaito, Yoshiyuki Hirano, Chihiro Sutoh, Siqing Guan, Yusuke Nitta, Yoshihito Ozawa, Yohei Kawasaki, Toshiyuki Ohtani, Jiro Masuya, Noriko Takahashi, Noriyuki Sato, Shizuka Nakamura, Akiko Nakagawa, Eiji Shimizu
Summary: The study found that the ACAT program has a positive impact on increasing understanding of autistic attributes among autistic adolescents and their parents/guardians, reducing treatment stigma, and improving mental health for autistic adolescents. However, it does not significantly affect the mental health and adaptive skills of parents/guardians.
Article
Psychiatry
Ebba Du Rietz, Erik Pettersson, Isabell Brikell, Laura Ghirardi, Qi Chen, Catharina Hartman, Paul Lichtenstein, Henrik Larsson, Ralf Kuja-Halkola
Summary: ADHD shows strong genetic associations with neurodevelopmental disorders, and its comorbidity is largely explained by genetically influenced general psychopathology. The link between ADHD and externalising or internalising disorders is weaker and influenced by non-shared environmental effects.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Psychology, Developmental
Lauren M. O'Reilly, Erik Pettersson, Patrick D. Quinn, E. David Klonsky, Jessie R. Baldwin, Sebastian Lundstrom, Henrik Larsson, Paul Lichtenstein, Brian M. D'Onofrio
Summary: The study revealed an independent association between bullying victimization and self-harm/suicide attempt in adolescence, with small effect sizes, indicating the need for additional interventions beyond bullying prevention.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Editorial Material
Psychiatry
Erik Pettersson, Henrik Larsson, Paul Lichtenstein
Article
Oncology
Yangjun Liu, Erik Pettersson, Anna Schandl, Sheraz Markar, Asif Johar, Pernilla Lagergren
Summary: Higher dispositional optimism is associated with better health-related quality of life after esophageal cancer surgery, with patients reporting better global quality of life, emotional function, social function, and less severe symptoms compared to those with lower dispositional optimism. Patients with moderately high dispositional optimism also showed significantly better global quality of life and less severe diarrhea. Adjusted mean score differences remained consistent across time points.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Psychology, Clinical
Erik Pettersson, Paul Lichtenstein, Henrik Larsson, Brian M. D'Onofrio, Benjamin B. Lahey, Antti Latvala
Summary: The study found associations between resting heart rate and general intelligence with psychopathology models, suggesting that intelligence may be a transdiagnostic risk factor for any form of psychopathology.
CLINICAL PSYCHOLOGICAL SCIENCE
(2021)
Article
Psychology, Clinical
Laura Ghirardi, Ralf Kuja-Halkola, Erik Pettersson, Amir Sariaslan, Louise Arseneault, Seena Fazel, Brian M. D'Onofrio, Paul Lichtenstein, Henrik Larsson
Summary: This study investigated the association between neurodevelopmental disorders (NDs) and violent victimization in adolescence and young adulthood. The study found that females with NDs and males with attention-deficit/hyperactivity disorder (ADHD) were at a higher risk of violent victimization. Familial factors and externalizing problems may play important roles in this association.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Oncology
Yangjun Liu, Erik Pettersson, Anna Schandl, Sheraz Markar, Asif Johar, Pernilla Lagergren
Summary: The study revealed that psychological distress post-esophageal cancer surgery increases over 1 to 2 years, with higher levels of dispositional optimism associated with lower distress risk.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Psychology, Developmental
Cen Chen, Yi Lu, Sebastian Lundstrom, Henrik Larsson, Paul Lichtenstein, Erik Pettersson
Summary: The study found that polygenic risk scores (PRS) are directly associated with psychiatric symptoms rather than being caused by indirect pathways.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Oncology
Yangjun Liu, Erik Pettersson, Anna Schandl, Sheraz Markar, Asif Johar, Pernilla Lagergren
Summary: This study examines the association between dispositional optimism and all-cause mortality after esophageal cancer surgery, considering the effects of tumor stage and the COVID-19 pandemic. It finds that higher dispositional optimism is associated with lower risk of all-cause mortality, especially among patients with early and intermediate esophageal cancer and before the COVID-19 pandemic.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Psychology, Developmental
Lauren O'Reilly, Kit K. Elam, Patrick D. Quinn, Sydney Adams, Marianne G. Chirica, E. David Klonsky, Erik Pettersson, Sebastian Lundstrom, Henrik Larsson, Paul Lichtenstein, Brian D'Onofrio
Summary: Sports participation, physical activity, and friendship quality are believed to protect against self-harm and substance use behavior in adolescence, but previous studies have produced mixed results. Using a twin control design, this study found that parent-reported sports participation and twin-reported positive friendship quality were associated with increased odds of alcohol problems and nicotine use, while parent-reported sports participation, twin-reported physical activity, and twin-reported friendship quality were associated with decreased odds of self-harm behavior.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2022)
Article
Multidisciplinary Sciences
Alexander Neumann, Ilja M. Nolte, Irene Pappa, Tarunveer S. Ahluwalia, Erik Pettersson, Alina Rodriguez, Andrew Whitehouse, Catharina E. M. van Beijsterveldt, Beben Benyamin, Anke R. Hammerschlag, Quinta Helmer, Ville Karhunen, Eva Krapohl, Yi Lu, Peter J. van der Most, Teemu Palviainen, Beate St Pourcain, Ilkka Seppaelae, Anna Suarez, Natalia Vilor-Tejedor, Carla M. T. Tiesler, Carol Wang, Amanda Wills, Ang Zhou, Silvia Alemany, Hans Bisgaard, Klaus Bonnelykke, Gareth E. Davies, Christian Hakulinen, Anjali K. Henders, Elina Hyppoenen, Jakob Stokholm, Meike Bartels, Jouke-Jan Hottenga, Joachim Heinrich, John Hewitt, Liisa Keltikangas-Jaervinen, Tellervo Korhonen, Jaakko Kaprio, Jari Lahti, Marius Lahti-Pulkkinen, Terho Lehtimaeki, Christel M. Middeldorp, Jackob M. Najman, Craig Pennell, Chris Power, Albertine J. Oldehinkel, Robert Plomin, Katri Raeikkoenen, Olli T. Raitakari, Kaili Rimfeld, Laerke Sass, Harold Snieder, Marie Standl, Jordi Sunyer, Gail M. Williams, Marian J. Bakermans-Kranenburg, Dorret I. Boomsma, Marinus H. van IJzendoorn, Catharina A. Hartman, Henning Tiemeier
Summary: The study identifies genetic variants associated with general psychopathology in childhood and their shared effects with common psychiatric disorders. These variants are also correlated with intelligence, educational attainment, wellbeing, smoking, and body fat.
Article
Medicine, General & Internal
C. Chen, E. Pettersson, A. G. Summit, K. Boersma, Z. Chang, R. Kuja-Halkola, P. Lichtenstein, P. D. Quinn
Summary: Understanding the relationship between chronic pain and suicidal behavior is important for suicide prevention. The study found that the association between chronic pain and suicidal behavior may be attributed to unmeasured confounding or pain comorbidity. However, the association was not statistically significant within monozygotic twin pairs, suggesting the presence of familial confounding.
Article
Psychiatry
Erik Pettersson, Henrik Larsson, Brian Mathew D'Onofrio, Paul Lichtenstein
Summary: This study investigates the associations between psychopathology factors and clinically relevant outcomes within family pairs. The results suggest that interventions targeting broad psychopathology dimensions might help reduce the risk of future adverse events.
Meeting Abstract
Behavioral Sciences
Cen Chen, Erik Pettersson, Alynna Summit, Katja Boersma, Zheng Chang, Ralf Kuja-Halkola, Paul Lichtenstein, Patrick Quinn
Meeting Abstract
Health Care Sciences & Services
Yangjun Liu, Erik Pettersson, Anna Schandl, Sheraz Markar, Asif Johar, Pernilla Lagergren
QUALITY OF LIFE RESEARCH
(2021)
