Transcriptome profiling in engrailed-2 mutant mice reveals common molecular pathways associated with autism spectrum disorders

The Genetic Landscapes of Autism Spectrum Disorders

(2013) Guillaume Huguet et al.   Annual Review of Genomics and Human Genetics

Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

(2013) S J James et al.   Translational Psychiatry

Interneuron, interrupted: molecular pathogenesis of ARX mutations and X-linked infantile spasms

(2012) Pedro R Olivetti et al.   CURRENT OPINION IN NEUROBIOLOGY

The engrailed homeobox genes are required in multiple cell lineages to coordinate sequential formation of fissures and growth of the cerebellum

(2012) Grant D. Orvis et al.   DEVELOPMENTAL BIOLOGY

SCN1A Mutation Associated With Intractable Myoclonic Epilepsy and Migraine Headache

(2012) Patrick Frosk et al.   JOURNAL OF CHILD NEUROLOGY

The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

(2012) Elisa S Na et al.   NEUROPSYCHOPHARMACOLOGY

Autism-Relevant Social Abnormalities and Cognitive Deficits in Engrailed-2 Knockout Mice

(2012) Jennifer Brielmaier et al.   PLoS One

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

(2012) Joseph D Buxbaum et al.   Molecular Autism

Functional morphological imaging of autism spectrum disorders: Current position and theories proposed

(2012) M.-A. Lauvin et al.   Diagnostic and Interventional Imaging

Rare Deletions at the Neurexin 3 Locus in Autism Spectrum Disorder

(2011) Andrea K. Vaags et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

(2011) Chiara Verpelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults

(2011) Daniel Alvarez-Fischer et al.   NATURE NEUROSCIENCE

Gene expression studies in autism: Moving from the genome to the transcriptome and beyond

(2011) Irina Voineagu   NEUROBIOLOGY OF DISEASE

Expression Profiling of Autism Candidate Genes during Human Brain Development Implicates Central Immune Signaling Pathways

(2011) Mark N. Ziats et al.   PLoS One

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum

(2010) Y. Cheng et al.   DEVELOPMENT

Engrailed Homeobox Genes Regulate Establishment of the Cerebellar Afferent Circuit Map

(2010) R. V. Sillitoe et al.   JOURNAL OF NEUROSCIENCE

Genome-wide expression studies in Autism spectrum disorder, Rett syndrome, and Down syndrome

(2010) Carla Lintas et al.   NEUROBIOLOGY OF DISEASE

Autism-Associated Haplotype Affects the Regulation of the Homeobox Gene, ENGRAILED 2

(2009) Rym Benayed et al.   BIOLOGICAL PSYCHIATRY

Increased susceptibility to kainic acid–induced seizures in Engrailed-2 knockout mice

(2009) P.P. Tripathi et al.   NEUROSCIENCE

Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy

(2009) J. C. Oakley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engrailed-2 regulates genes related to vesicle formation and transport in cerebellar Purkinje cells

(2008) Martin I. Holst et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Immune transcriptome alterations in the temporal cortex of subjects with autism

(2008) Krassimira Garbett et al.   NEUROBIOLOGY OF DISEASE