Article
Public, Environmental & Occupational Health
Tsung Yu, Yueh-Ju Lien, Fu-Wen Liang, Pao-Lin Kuo
Summary: The study from Taiwan suggests that parental socioeconomic status is associated with the risk of autism spectrum disorder in offspring, with higher SES independently correlated with higher ASD risk. In contrast, higher SES was independently associated with lower risk of intellectual disability. Potential factors related to socio-economic status may contribute to the positive relation of SES and ASD risk.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Jingyuan Xiao, Yu Gao, Yongfu Yu, Gunnar Toft, Yawei Zhang, Jiajun Luo, Yuntian Xia, Katarzyna Chawarska, Jorn Olsen, Jiong Li, Zeyan Liew
Summary: Offspring of parents born with adverse characteristics had an elevated risk for ASD, with parents born very preterm potentially doubling the risk for their children. Parental social-mental and offspring perinatal factors may explain a portion of this risk.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Behavioral Sciences
Yi-Ling Chien, Chi-Shin Wu, Yen-Chen Chang, Mei-Leng Cheong, Tsung-Chieh Yao, Hui-Ju Tsai
Summary: Parental psychiatric disorders, including schizophrenia, depressive disorders, obsessive-compulsive disorder, adjustment disorders, ADHD and ASD, are associated with ASD in offspring.
Review
Medicine, General & Internal
Cheuk-Kwan Sun, Yu-Shian Cheng, I-Wen Chen, Hsien-Jane Chiu, Weilun Chung, Ruu-Fen Tzang, Hsin-Yi Fan, Chia-Wei Lee, Kuo-Chuan Hung
Summary: This study investigated the association between parental rheumatoid arthritis (RA) and the risk of offspring autism spectrum disorder (ASD). The results showed a significant association between maternal RA and offspring ASD risk, while no association was found between paternal RA and offspring ASD risk. The timing of maternal RA diagnosis did not affect the risk of offspring ASD, and the association between maternal RA and offspring ASD risk was consistent across different geographical locations.
FRONTIERS IN MEDICINE
(2022)
Article
Psychology, Multidisciplinary
Yuanting Lin, Yan Wang, Chunhui Lin, Qingnan Ni, Ruolin Jia, Yanling Chang, YuanPing Qi
Summary: This study examines the connection between parental burnout and alexithymia among parents of autistic children. It finds that parents of autistic children are more prone to experiencing parental burnout, and there is a relationship between parental burnout and parents' personality traits. The study also reveals that social support is negatively related to both alexithymia and parental burnout.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Multidisciplinary Sciences
Masud Rabbani, Munirul M. Haque, Dipranjan Das Dipal, Md Ishrak Islam Zarif, Anik Iqbal, Amy Schwichtenberg, Naveen Bansal, Tanjir Rashid Soron, Syed Ishtiaque Ahmed, Sheikh Iqbal Ahamed
Summary: This study aimed to evaluate the behavioral patterns of children with ASD during and after the COVID-19 lockdown, and found that support in the areas of problematic behavior could mitigate future risks.
SCIENTIFIC REPORTS
(2021)
Review
Psychiatry
Pierre Ellul, Eric Acquaviva, Hugo Peyre, Michelle Rosenzwajg, Pierre Gressens, David Klatzmann, Richard Delorme
Summary: This study investigates the association between autoimmune or inflammatory disorders (AID) in parents and the risk of neurodevelopmental disorders (NDD) in their children. The results show that mothers and fathers with AID are associated with an increased risk of Autism Spectrum Disorder (ASD) and Attention-Deficit Hyperactivity Disorder (ADHD) in their offspring, but the strength of this association varies in AID-specific analyses.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Psychology, Developmental
Anna V. Oppenheimer, Marc G. Weisskopf, Kristen Lyall
Summary: The purpose of this study was to determine if the short form of the Social Responsiveness Scale (SRS-SF) can replicate prior familiality findings for the full SRS. The results showed that parental SRS-SF scores were associated with child ASD diagnoses and child SRS-SF scores, similar to findings for the full SRS.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Psychology, Developmental
Marisa A. Patti, Xuejuan Ning, Mina Hosseini, Lisa A. Croen, Robert M. Joseph, Margaret R. Karagas, Christine Ladd-Acosta, Rebecca Landa, Daniel S. Messinger, Craig J. Newschaffer, Ruby Nguyen, Sally Ozonoff, T. Michael O'Shea, Rebecca J. Schmidt, Cindy O. Trevino, Kristen Lyall
Summary: The study compared the performance of the full and shortened versions of the Social Responsiveness Scale (SRS) in assessing ASD risk factors. The results showed that the associations between the two versions were highly comparable. This suggests that the shortened SRS can be used to assess ASD-related risk factors and is important for reducing participant burden in large-scale research studies.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Environmental Sciences
Ja Hyeong Kim, Qi Yan, Karan Uppal, Xin Cui, Chenxiao Ling, Douglas I. Walker, Julia E. Heck, Ondine S. von Ehrenstein, Dean P. Jones, Beate Ritz
Summary: This study identified metabolic pathways disturbed in mothers with ASD offspring among women experiencing high exposure to traffic-related air pollution during pregnancy that were associated with mitochondrial dysfunction, providing a better understanding of metabolic disturbances involved in the development of ASD under adverse environmental conditions.
ENVIRONMENTAL RESEARCH
(2021)
Article
Medicine, General & Internal
Gillian E. Hanley, Celeste Bickford, Angie Ip, Nancy Lanphear, Bruce Lanphear, Whitney Weikum, Lonnie Zwaigenbaum, Tim F. Oberlander
Summary: Maternal use of epidural analgesia during labor and delivery was found to be associated with a small increase in the risk of autism spectrum disorder in offspring in this population-based retrospective cohort study. However, due to potential residual confounding factors, these findings do not provide strong supporting evidence for this association.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Medicine, General & Internal
Meritxell Fernandez-Lafitte, Jesus Cobo, Ramon Coronas, Isabel Parra, Joan Carles Oliva, Aida alvarez, Susanna Esteba-Castillo, Olga Gimenez-Palop, Diego J. Palao, Assumpta Caixas
Summary: This study explored symptoms of autism spectrum disorder (ASD) in adults with Prader-Willi syndrome (PWS), focusing on their psychosocial functionality. The results showed that impaired social responsiveness was common in participants with PWS and had a significant impact on their overall functionality, particularly in social and personal relationships. The study highlights the importance of assessing social skills in psychosocial evaluations of PWS patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Shuyun Chen, Mengyu Fan, Brian K. Lee, Christina Dalman, Hakan Karlsson, Renee M. Gardner
Summary: This study investigated the associations between gestational weight gain (GWG) and risks of neurodevelopmental disorders (NDDs) in offspring, specifically autism spectrum disorder (ASD), intellectual disability (ID), and attention deficit/hyperactivity disorder (ADHD). The findings suggest that the timing and rate of weight gain during pregnancy have different effects on the risk of NDDs in children.
Review
Nutrition & Dietetics
Catherine Friel, Alastair H. Leyland, Jana J. Anderson, Alexandra Havdahl, Tiril Borge, Michal Shimonovich, Ruth Dundas
Summary: This study reviewed the relationship between prenatal multivitamin supplements and offspring autism, finding a trend of reduced autism risk in high-quality observational studies but no overall robust association. However, the application of causal inference was limited, and the quality of evidence needs to be improved.
Article
Psychology, Developmental
Dunia Garrido, Dafina Petrova, Edward Cokely, Gloria Carballo, Rocio Garcia-Retamero
Summary: The study found a correlation between parents' numeracy and the family quality of life of children with ASD, independent of other factors. Parental risk literacy skills may impact decision-making vulnerabilities, affecting family outcomes such as FQoL.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2021)
Article
Public, Environmental & Occupational Health
Andrea L. Roberts, Zeyan Liew, Kristen Lyall, Alberto Ascherio, Marc G. Weisskopf
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2018)
Article
Immunology
Jennifer A. Sumner, Qixuan Chen, Andrea L. Roberts, Ashley Winning, Eric B. Rimm, Paola Gilsanz, M. Maria Glymour, Shelley S. Tworoger, Karestan C. Koenen, Laura D. Kubzansky
BRAIN BEHAVIOR AND IMMUNITY
(2018)
Article
Endocrinology & Metabolism
S. Bryn Austin, Margaret Rosario, Katie A. McLaughlin, Andrea L. Roberts, Vishnudas Sarda, Kimberly Yu, Stacey Missmer, Laura Anatale-Tardiff, Emily A. Scherer
PSYCHONEUROENDOCRINOLOGY
(2018)
Article
Public, Environmental & Occupational Health
Zeyan Liew, Marianthi-Anna Kioumourtzoglou, Andrea L. Roberts, Eilis J. O'Reilly, Alberto Ascherio, Marc G. Weisskopf
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2019)
Article
Rheumatology
Candace H. Feldman, Susan Malspeis, Cianna Leatherwood, Laura Kubzansky, Karen H. Costenbader, Andrea L. Roberts
JOURNAL OF RHEUMATOLOGY
(2019)
Article
Oncology
Andrea L. Roberts, Tianyi Huang, Karestan C. Koenen, Yongjoo Kim, Laura D. Kubzansky, Shelley S. Tworoger
Article
Public, Environmental & Occupational Health
Andrea L. Roberts, Herman A. Taylor, Alicia J. Whittington, Ross D. Zafonte, Frank E. Speizer, Alvaro Pascual-Leone, Aaron Baggish, Marc G. Weisskopf
ANNALS OF EPIDEMIOLOGY
(2020)
Article
Oncology
Rebecca B. Lawn, Kristen M. Nishimi, Yongjoo Kim, Sun Jae Jung, Andrea L. Roberts, Jennifer A. Sumner, Rebecca C. Thurston, Lori B. Chibnik, Eric B. Rimm, Andrew D. Ratanatharathorn, Shaili C. Jha, Karestan C. Koenen, Shelley S. Tworoger, Laura D. Kubzansky
Summary: Based on data from the Nurses' Health Study II, the study found that trauma and number of PTSD symptoms were associated with a greater likelihood of initiating MHT use in a dose-response manner. There was evidence of effect modification by age at baseline, suggesting age is an important factor influencing this association.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Biochemistry & Molecular Biology
Andrew Ratanatharathorn, Karestan C. Koenen, Lori B. Chibnik, Marc G. Weisskopf, Janet W. Rich-Edwards, Andrea L. Roberts
Summary: Research suggests that childhood abuse may be associated with genetic risk for mental illness, with an increase in genetic risk linked to a higher risk of experiencing childhood abuse, particularly in terms of ADHD and MDD.
MOLECULAR PSYCHIATRY
(2021)
Article
Psychology, Clinical
Rebecca B. Lawn, Shaili C. Jha, Jiaxuan Liu, Laura Sampson, Audrey R. Murchland, Jennifer A. Sumner, Andrea L. Roberts, Seth G. Disner, Francine Grodstein, Jae H. Kang, Laura D. Kubzansky, Lori B. Chibnik, Karestan C. Koenen
Summary: The study found that head injury, PTSD, and depression were prevalent in civilian women. The combination of PTSD and depression was associated with worse cognitive performance, especially among women with a history of head injury. Further exploration of head injury in relation to PTSD, depression, and cognition in women is needed for future studies.
DEPRESSION AND ANXIETY
(2022)
Article
Multidisciplinary Sciences
Andrew Ratanatharathorn, Lori B. Chibnik, Karestan C. Koenen, Marc G. Weisskopf, Andrea L. Roberts
Summary: This study found that genetic risk for mental illness is associated with perinatal risk factors such as smoking during pregnancy, breastfeeding for less than 1 month, experience of intimate partner violence in the year before birth, and pregestational overweight or obesity. These results suggest that genetic risk might account for the associations between perinatal conditions and mental illness in offspring.
Article
Oncology
Andrea L. Roberts, Andrew Ratanatharathorn, Lori Chibnik, Laura D. Kubzansky, Shelley S. Tworoger
Summary: This study found that multiple factors related to psychological distress are associated with ovarian cancer risk. Over a 21-year follow-up period, five distress-related factors were repeatedly measured. The results showed that women with three or more distress-related factors had an increased risk of ovarian cancer, including posttraumatic stress disorder (PTSD) as a significant factor.
Article
Psychology, Clinical
Roger W. Strong, Rachel Grashow, Andrea L. Roberts, Eliza Passell, Luke Scheuer, Douglas P. Terry, Sarah Cohan, Alvaro Pascual-Leone, Marc G. Weisskopf, Ross D. Zafonte, Laura T. Germine
Summary: This cross-sectional study examined the association between football exposure and later life cognitive performance in former professional American-style football players. It found that retrospectively reported football concussion symptoms were associated with cognitive performance in later life. However, this association may differ based on pre-concussion cognitive functioning.
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
(2023)
Article
Family Studies
Andrea L. Roberts, Jennifer A. Sumner, Karestan C. Koenen, Laura D. Kubzansky, Francine Grodstein, Janet Rich-Edwards, Marc G. Weisskopf
Summary: Childhood abuse is found to be negatively associated with cognitive function in middle age, with poorer scores in learning/working memory and psychomotor speed/attention. This association is partially influenced by adulthood socioeconomic status and health factors, and is further weakened when psychological distress is taken into account.
CHILD MALTREATMENT
(2022)
Article
Criminology & Penology
Avanti Adhia, Allegra R. Gordon, Andrea L. Roberts, Garrett M. Fitzmaurice, David Hemenway, S. Bryn Austin
Summary: The study found that males in the top decile of childhood gender nonconformity were at higher risk of intimate partner violence victimization and perpetration in adolescence and early adulthood, while there was no similar association for females. Childhood abuse did not mediate the relationship between nonconformity and intimate partner violence. This highlights the importance of gender nonconformity as a risk indicator for IPV among young adult males.
JOURNAL OF INTERPERSONAL VIOLENCE
(2021)