Article
Gastroenterology & Hepatology
Ali Osman, Manal M. Albashir, Kalyana Nandipati, Ryan W. Walters, Subhash Chandra
Summary: The systematic review and meta-analysis demonstrated a consistent association between abnormal GEFV indicated by Hill's classification III/IV and symptomatic GERD and erosive esophagitis. It is recommended to include Hill's classification in routine endoscopy reports and workup for GERD.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Medicine, General & Internal
Hyeon Hui Kang, Minji Seo, Jongmin Lee, So Young Ha, Jung Hwan Oh, Sang Haak Lee
Summary: In this study, over half of patients with COPD were diagnosed with RE, but RE was not associated with age, sex, smoking history, or severity of airflow limitation. AECOPD was also not related to the presence or severity of RE. The use of theophylline may increase the risk of RE in COPD patients.
Article
Medicine, General & Internal
Lukas Horvath, Karolos Fostiropoulos, Emanuel Burri, Marcel Kraft
Summary: Transnasal esophagoscopy (TNE) has high sensitivity, specificity, and accuracy in diagnosing LPR, with common pathological findings including insufficient cardia, hiatal hernia, lymphoid follicles, and visible reflux.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Gastroenterology & Hepatology
Joan W. Chen, Marcelo F. Vela, Kathryn A. Peterson, Dustin A. Carlson
Summary: This article provides practical advice for the clinical management of patients with suspected extraesophageal gastroesophageal reflux disease. The advice is based on available evidence from published studies, clinical trials, and clinical guidelines. It emphasizes the importance of considering extraesophageal manifestations of gastroesophageal reflux disease and the need for a multidisciplinary approach in diagnosis and treatment.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
C. Prakash Gyawali, Rena Yadlapati, Ronnie Fass, David Katzka, John Pandolfino, Edoardo Savarino, Daniel Sifrim, Stuart Spechler, Frank Zerbib, Mark R. Fox, Shobna Bhatia, Nicola de Bortoli, Yu Kyung Cho, Daniel Cisternas, Chien-Lin Chen, Charles Cock, Albis Hani, Jose Maria Remes Troche, Yinglian Xiao, Michael F. Vaezi, Sabine Roman
Summary: The Lyon Consensus 2.0 provides conclusive criteria for diagnosing gastro-oesophageal reflux disease (GERD) and offers additional metrics to support or refute the diagnosis when primary criteria are inconclusive. A global team evaluated research since the original Lyon Consensus and collaborated on developing statements to update criteria. The updated consensus includes a modern definition of actionable GERD, describes the likelihood of symptoms being related to reflux episodes, and provides diagnostic strategies and testing options based on proven or unproven GERD.
Review
Medicine, General & Internal
Dagmar K. Tiemens, Leenke van Haaften, Erika Leenders, Annemiek M. J. van Wegberg, Bregtje Gunther Moor, Joyce Geelen, Jos M. T. Draaisma
Summary: Noonan syndrome patients often experience feeding problems in infancy and childhood, which can significantly affect their quality of life. The mechanisms behind these problems are complex, and the treatment requires a multidisciplinary approach.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Duc Trong Quach, Quoc Van Ha, Chuyen Thi-Ngoc Nguyen, Quang Dinh Le, Doan Thi-Nha Nguyen, Nhu Thi-Hanh Vu, Ngoc Le-Bich Dang, Nhan Quang Le
Summary: This study aimed to assess the overlap rate of gastroesophageal reflux disease (GERD) and functional dyspepsia (FD) and the yield of esophagogastroduodenoscopy in patients clinically presenting with FD. The results showed that GERD-FD overlap was more common than each disorder alone, with postprandial distress syndrome being significantly prominent. Organic dyspepsia was uncommon in patients clinically fulfilling the Rome IV criteria for FD.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Yung-An Tsou, Sheng-Hwa Chen, Wen-Chieh Wu, Ming-Hsui Tsai, David Bassa, Liang-Chun Shih, Wen-Dien Chang
Summary: This study investigated the clinical assessments and extent of esophageal pressure changes in LRPD patients with varying severities of GERD. It found that patients with more severe GERD had lower esophageal sphincter pressures, with the lowest pressures observed in patients with grade D GERD. No significant differences in esophageal pressures were noted based on age, gender, or BMI among the patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Gastroenterology & Hepatology
Sheng Chen, Feng Du, Changqing Zhong, Caifang Liu, Xiaoying Wang, Yan Chen, Gang Wang, Xiaopei Gao, Lu Zhang, Lianyong Li, Wei Wu
Summary: Innovations in endoscopy have significantly improved the diagnosis and treatment of GERD. Endoscopy and biopsies can directly observe and determine esophageal abnormalities. Future research should focus on personalized treatment and the primary pathophysiology of GERD.
GASTROENTEROLOGY REPORT
(2021)
Article
Medicine, Research & Experimental
Di Lu, Chun Shan Bi, Xue Wei, Bao Na Guo, Ying Xin Gao, Jing Chen, Jie Qian, Zi Hao Guo, Yan Bin Wang, Li Li, Chuan Zhang, Jian Yu Hao, Yan Gao
Summary: This study assessed the safety and efficacy of endoscopic radiofrequency therapy under direct vision in GERD patients. The results showed that treatment under direct vision improved symptoms and lower esophageal sphincter pressure in patients at up to 12 months.
MEDICAL SCIENCE MONITOR
(2022)
Article
Gastroenterology & Hepatology
Yuto Shimamura, Haruhiro Inoue, Enrique Rodriguez de Santiago, Mary Raina Angeli Abad, Yusuke Fujiyoshi, Akiko Toshimori, Mayo Tanabe, Kazuya Sumi, Yugo Iwaya, Haruo Ikeda, Manabu Onimaru
Summary: The Endoscopic Pressure Study Integrated System (EPSIS) is a new diagnostic tool for GERD that shows good accuracy in diagnosing the condition by assessing intragastric pressure waveform patterns. In this study, analysis of EPSIS parameters, specifically pressure difference and waveform gradient, demonstrated high diagnostic accuracy for abnormal acid reflux in patients with GERD symptoms.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Zaheer Nabi, Mohan Ramchandani, Mahiboob Sayyed, Radhika Chavan, Santosh Darisetty, Rajesh Goud, H. V. V. Murthy, D. Nageshwar Reddy
Summary: The study indicates that in patients with achalasia, short esophageal myotomy is comparable to long myotomy in terms of clinical success, operative time, and GERD. Short esophageal myotomy can reduce operating duration efficiently.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Jian He, Yani Yin, Wen Tang, Jiahui Jiang, Lei Gu, Jun Yi, Lu Yan, Shuijiao Chen, Yu Wu, Xiaowei Liu
Summary: L-ARMS is an effective and safe procedure for controlling GERD symptoms, esophageal acid exposure, and lower esophageal sphincter pressure, which can be performed endoscopically in a time-saving and simple manner.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Surgery
Joseph J. Fantasia, Charles Cock, David I. Watson, Tim Bright, Sarah K. Thompson
Summary: Gastroesophageal reflux disease affects a significant portion of the population worldwide. Minimally invasive laparoscopic fundoplication is an effective treatment for selected patients. However, a small percentage of patients may require revisional surgery. Endoscopy plays an important role in evaluating the outcomes of fundoplication surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Biochemistry & Molecular Biology
Xin Li, Hitesh Singh Chaouhan, Yao-Ming Wang, I-Kuan Wang, Cheng-Li Lin, Te-Chun Shen, Chi-Yuan Li, Kuo-Ting Sun
Summary: This study found that patients with GERD have a higher risk of developing periodontitis compared to those without GERD. Age, sex, and the presence of comorbidities also increase the risk of periodontitis in GERD patients. An increased number of emergency room visits is associated with a higher risk of periodontitis.
Article
Health Care Sciences & Services
Barbara W. Trautner, Pooja Prasad, Larissa Grigoryan, Sylvia J. Hysong, Jennifer R. Kramer, Suja Rajan, Nancy J. Petersen, Tracey Rosen, Dimitri M. Drekonja, Christopher Graber, Payal Patel, Paola Lichtenberger, Timothy P. Gauthier, Steve Wiseman, Makoto Jones, Anne Sales, Sarah Krein, Aanand Dinkar Naik
IMPLEMENTATION SCIENCE
(2018)
Article
Health Care Sciences & Services
Joseph Mignogna, Lindsey Ann Martin, Juliette Harik, Natalie E. Hundt, Michael Kauth, Aanand D. Naik, Kristen Sorocco, Justin Benzer, Jeffrey Cully
IMPLEMENTATION SCIENCE
(2018)
Article
Public, Environmental & Occupational Health
Molly J. Horstman, Andrew M. Spiegelman, Aanand D. Naik, Barbara W. Trautner
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2018)
Article
Multidisciplinary Sciences
Mary Tinetti, Lilian Dindo, Cynthia Daisy Smith, Caroline Blaum, Darce Costello, Gregory Ouellet, Jonathan Rosen, Kizzy Hernandez-Bigos, Mary Geda, Aanand Naik
Article
Geriatrics & Gerontology
Bruna Martins-Klein, Patricia A. Bamonti, Montgomery Owsiany, Aanand Naik, Jennifer Moye
Summary: This study investigated sources of stress related to cancer diagnosis and treatment, finding that older adults less frequently reported psychological uncertainty, social stress, and situational stress, but all age groups reported similar rates of physical stress. Older adults more often made spontaneous references to emotion regulation, and those who reported stress without emotion regulation in qualitative comments had higher emotional distress.
AGING & MENTAL HEALTH
(2021)
Article
Geriatrics & Gerontology
Whitney L. Mills, Mark E. Kunik, P. Adam Kelly, Nancy L. Wilson, Steven Starks, Ali Asghar-Ali, Hannah Curren-Vo, Aanand D. Naik
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2020)
Article
Medical Informatics
Javad Razjouyan, Jennifer Freytag, Lilian Dindo, Lea Kiefer, Edward Odom, Jaime Halaszynski, Jennifer W. Silva, Aanand D. Naik
Summary: This study developed and validated an NLP model to reliably document clinicians identifying patient priorities in the EHR as a measure of PPC adoption. The NLP model exhibited high accuracy, recall, and precision in both training and validation stages. Compared to a simple search term approach, the NLP model achieved higher precision in identifying PPC language in patient notes.
JMIR MEDICAL INFORMATICS
(2021)
Article
Multidisciplinary Sciences
Jennifer Arney, Caroline Gray, Jack A. Clark, Donna Smith, Annie Swank, Daniel D. Matlock, Jennifer Melcher, Fasiha Kanwal, Aanand D. Naik
Summary: Prognosis discussions for patients with advanced liver disease (AdvLD) are important and should be conducted early, including discussions about life expectancy, disease course predictions, and changes in function and capabilities. Structured and routine prognosis discussions should be part of AdvLD care.
Article
Health Care Sciences & Services
Astrid Grouls, Eberechi Nwogu-Onyemkpa, Danielle Guffey, Subhasis Chatterjee, James P. Herlihy, Aanand D. Naik
Summary: Among COVID-19 patients receiving ECMO, PCC may be associated with a shift to DNAR status, particularly with automatic PCC. This may have further impacts on length of stay, duration of time on ECMO, and end-of-life care plan.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Medicine, General & Internal
Eberechi Nwogu-Onyemkpa, Deepa Dongarwar, Hamisu M. Salihu, Lois Akpati, Maricarmen Marroquin, Megan Abadom, Aanand D. Naik
Summary: This study aimed to evaluate the use of palliative care services during hospitalizations of adult patients with sickle cell disease (SCD). The study found that the use of palliative care services during SCD-related hospitalizations is increasing but remains low. Disparities associated with race and gender exist, highlighting the need for further research to guide comprehensive and equitable care for adult patients with SCD.
Article
Medicine, General & Internal
Jennifer Arney, Caroline Gray, Anne M. Walling, Jack A. Clark, Donna Smith, Jennifer Melcher, Steven Asch, Fasiha Kanwal, Aanand D. Naik
Summary: This study aims to present two divergent mental models of integrated advanced liver disease (AdvLD) care among healthcare providers. Two mental models were identified, differing in the timing and delivery of care elements. Participants emphasized the importance of multidisciplinary teams integrating supportive care, symptom management, and end-of-life care with liver disease care.
Article
Endocrinology & Metabolism
Jeffrey S. Gonzalez, Heidi Krause-Steinrauf, Ionut Bebu, Gladys Crespo-Ramos, Claire J. Hoogendoorn, Aanand D. Naik, Andrea Waltje, Elizabeth Walker, Dominic Ehrmann, Andrea Cherrington
Summary: This study examined the association between emotional distress and metformin adherence, overall diabetes self-management, and glycemic control in adults with early type 2 diabetes. The results showed that depression symptoms and diabetes distress were significantly related to problematic diabetes self-management, but not to glycemic control.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Health Care Sciences & Services
Arash Maghsoudi, Sara Nowakowski, Ritwick Agrawal, Amir Sharafkhaneh, Mark E. Kunik, Aanand Naik, Hua Xu, Javad Razjouyan
Summary: This study used natural language processing to analyze social media content and assess the mental health conditions of people with insomnia after the COVID-19 outbreak. The study found that there was a higher likelihood of posting negative tweets about insomnia during the pandemic period and a higher probability of posting negative tweets after midnight. This research provides valuable information for understanding the impact of the COVID-19 pandemic on people's sleep behavior.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Editorial Material
Endocrinology & Metabolism
Aanand D. Naik
Article
Geriatrics & Gerontology
Katherine C. Ritchey, Laurence M. Solberg, Sandra Wolfe Citty, Lea Kiefer, Erica Martinez, Caroline Gray, Aanand D. Naik
Summary: This study evaluated the feasibility and quality of the health priorities identification (HPI) process in VA Community Living Centers (CLC), and found that HPI is an acceptable and feasible approach for aligning care with patient priorities in a CLC setting.
