Article
Engineering, Biomedical
Akihito Miyamoto, Hiroshi Kawasaki, Sunghoon Lee, Tomoyuki Yokota, Masayuki Amagai, Takao Someya
Summary: A method is reported for continuous monitoring of skin electrical resistance and transepidermal water loss, which can evaluate the barrier function of the skin and reflect the dynamic changes of skin physiology.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Medicine, General & Internal
Trinidad Montero-Vilchez, Juan-Angel Rodriguez-Pozo, Pablo Diaz-Calvillo, Maria Salazar-Nievas, Jesus Tercedor-Sanchez, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: The study aimed to evaluate the impact of dupilumab on skin barrier function in patients with atopic dermatitis (AD) and compare it with other treatments. The study found that dupilumab was more effective in improving barrier function in both eczematous lesions and non-lesioned skin compared to topical corticosteroids and cyclosporine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Konstantin Simon, Gila Oberender, Alexander Roloff
Summary: Tape stripping is a common method used in studies on drug penetration through the skin, but the amount of stratum corneum removed by each tape strip is still under debate. Some studies suggest that the amount of stratum corneum decreases with increasing depth, while others find a constant removal rate.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Medicine, General & Internal
Trinidad Montero-Vilchez, Maria-Victoria Segura-Fernandez-Nogueras, Isabel Perez-Rodriguez, Miguel Soler-Gongora, Antonio Martinez-Lopez, Ana Fernandez-Gonzalez, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: This study compared skin barrier function between healthy skin, psoriatic skin, and atopic dermatitis skin, finding that TEWL was higher at psoriatic and AD lesions, while SCH was lower. Specific TEWL and temperature values may help clinicians determine disease severity and treatment needs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Dermatology
Trinidad Montero-Vilchez, Antonio Martinez-Lopez, Carlos Cuenca-Barrales, Andrea Rodriguez-Tejero, Alejandro Molina-Leyva, Salvador Arias-Santiago
Summary: Wearing masks and gloves may impair skin homeostasis and epidermal barrier function, leading to increased transepidermal water loss and higher skin temperature. High-quality personal protective equipment should be provided, and appropriate skin prevention measures should be implemented.
Article
Multidisciplinary Sciences
Lars Ruether, Werner Voss
Summary: Five different galenics were analyzed for tissue breathability and gas exchange after 6 hours of application on pig ear skin. Hydrogel preparations showed higher breathability and moisture penetration, while Tyrosur (R) Care Expert Wound Gel and ointment exhibited sustained moisturizing effects.
Article
Veterinary Sciences
Adrien Idee, Marion Mosca, Didier Pin
Summary: This study evaluated the effect of a spot-on containing fatty acids, ceramides, and essential oils on the skin barrier function of dogs. The results showed that the spot-on had a protective effect on the skin barrier function. This suggests that the investigated product may be useful as an adjunctive treatment for canine atopic dermatitis.
VETERINARY SCIENCES
(2022)
Article
Peripheral Vascular Disease
Takahiro Ogura, Kento Kitada, Norihiko Morisawa, Yoshihide Fujisawa, Satoshi Kidoguchi, Daisuke Nakano, Hideki Kobara, Tsutomu Masaki, Jens Titze, Akira Nishiyama
Summary: This study investigated the pathogenesis of hypertension in spontaneously hypertensive rats and identified renal concentration ability and skin barrier function for water conservation as potential therapeutic targets for essential hypertension.
HYPERTENSION RESEARCH
(2023)
Article
Biology
Alicia Gonzalez-Bravo, Trinidad Montero-Vilchez, Salvador Arias-Santiago, Agustin Buendia-Eisman
Summary: Sunscreen may have a slight impact on the skin barrier function and skin homeostasis, reducing erythema and potentially displaying anti-inflammatory effects.
Article
Dermatology
Minjee Lee, Myun Soo Kim, Sung Hee Jang, Hayoung Kim, Gwang Seob Kim, Hyerin Lee, Hyun Min Park, Jungwoo Yang
Summary: Ferment lysates of Lacticaseibacillus rhamnosus IDCC 3201, known as Cera-Glow, were found to significantly improve skin barrier function by enhancing ceramide production and increasing skin hydration.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Chemistry, Applied
Kentaro Shoji, Aoi Kameda, Kayo Furuichi
Summary: Amazakes made from rice and koji mold are rich in nutrients and can improve skin moisturization. This study investigated the effect of milk amazake on skin function through a double-blind, randomized controlled trial. The results suggest that milk amazake may be useful as a functional food for improving skin function.
JOURNAL OF OLEO SCIENCE
(2023)
Article
Nutrition & Dietetics
Sebastien Holvoet, Sophie Nutten, Lenaick Dupuis, Dominique Donnicola, Tristan Bourdeau, Betsy Hughes-Formella, Dagmar Simon, Hans-Uwe Simon, Ryan S. Carvalho, Jonathan M. Spergel, Sibylle Koletzko, Carine Blanchard
Summary: This study demonstrates that oral supplementation with specific partially hydrolysed whey-based infant formulas can improve skin barrier function and reduce the risk of atopic dermatitis in infants. The formula was shown to decrease transepidermal water loss and total IgE levels, indicating a potential mechanism for reducing AD risk. Further human studies are needed to confirm the clinical efficacy of these findings.
Article
Dermatology
Sylwia Jarzabek, Helena Rotsztejn
Summary: The study involved 27 female subjects who received five oxygen microdermabrasion treatments every 2 weeks. Measurements of skin parameters were taken before and 2 weeks after the last treatment, with measurement points on the forehead, cheek, and nose petal. Results showed that oxybrasion treatments increase skin hydration and have a significant influence on the decrease of the skin hydrolipid coat and pH.
JOURNAL OF COSMETIC DERMATOLOGY
(2021)
Article
Medicine, Research & Experimental
Charles F. Schuler, Kelly M. O'Shea, Jonathan P. Troost, Bridgette Kaul, Christopher M. Launius, Jayme Cannon, David M. Manthei, George E. Freigeh, Georgiana M. Sanders, Simon P. Hogan, Nicholas W. Lukacs, James R. Baker Jr
Summary: The study found that an increase in TEWL during OFCs could predict positive clinical challenges. TEWL provides a monitoring modality that may predict food anaphylaxis and facilitate improvements in OFC safety and tolerability.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Review
Dermatology
Reva P. Peer, Anuk Burli, Howard Maibach
Summary: The study compared the stratum corneum function of skin of color and Caucasian skin, revealing contradictory results and the inability to draw conclusions. Further analysis and focus on experimental confounding variables affecting TEWL quantification are recommended.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2022)