Article
Neurosciences
Charles K. Davis, Saivenkateshkomal Bathula, Martin Hsu, Kahlilia C. Morris-Blanco, Anil K. Chokkalla, Soomin Jeong, Jeongwoo Choi, Shruti Subramanian, Jin Soo Park, Zsuzsanna Fabry, Raghu Vemuganti
Summary: The complex pathophysiology of post-traumatic brain damage may be effectively treated by a polypharmacological strategy, targeting multiple mechanisms simultaneously. A recent study on mice with traumatic brain injury (TBI) showed that a combination of three drugs resulted in improved motor and cognitive function, reduced secondary lesion volume, decreased oxidative DNA damage, and regulation of post-TBI inflammatory response.
JOURNAL OF NEUROSCIENCE
(2022)
Review
Cell Biology
Damien P. Kuffler
Summary: The gold standard technique for restoring nerve function with a gap is to use sensory autografts. However, this method only leads to good recovery in less than 50% of patients. This paper examines the potential of lithium to promote axon regeneration and suggests further clinical testing.
NEURAL REGENERATION RESEARCH
(2022)
Article
Clinical Neurology
Changmeng Zhang, Victor Kam Ho Lee, Jeremy Man Leung Yu, Jason Pui Yin Cheung, Paul Aarne Koljonen, Graham Ka Hon Shea
Summary: This study found that clinical and radiological parameters can predict neurological recovery rates in patients with acute traumatic central cord injury syndrome (CCS). Surgical decompression performed after the acute injury phase did not improve neurological outcomes.
Article
Clinical Neurology
Michelle H. Chen, Nancy D. Chiaravalloti, John DeLuca
Summary: Cognitive impairment is a common and disabling symptom in multiple sclerosis, with limited evidence supporting the efficacy of disease-modifying therapies in treating cognitive dysfunction. Cognitive rehabilitation in MS has shown promise in the past decade, with both restorative and compensatory programs proving efficacious. Clinicians should consider this low-cost, low-risk, yet effective treatment approach for their patients.
JOURNAL OF NEUROLOGY
(2021)
Article
Environmental Studies
Zengrong Li, Yanqiu Wu, Ehsan Rasoulinezhad, Yishen Sheng, Chunyu Bi
Summary: The impacts of efficiency in natural resource utilization on green economic recovery were measured for the case of five Central Asian countries from 2000 to 2021 through the Panel ARDL approach. The primary findings confirmed that resource efficiency has a positive effect on green economic growth in the industrial and agricultural sectors. The panel causality test also found a bi-directional causal linkage between industry's green economic growth and resource efficiency, while green economic growth in agriculture is caused by efficiency in natural resource deployment.
Article
Environmental Studies
Xiaofeng Hu
Summary: Using the Panel ARDL approach, this research measures the impacts of efficiency in natural resource utilization on green economic recovery in five Central Asian countries from 2000 to 2021. The primary findings indicate that natural resource utilization efficiency has a positive effect on green economic growth in the industrial and agricultural sectors of the region. Furthermore, the panel causality test confirms a bi-directional causal linkage between green economic growth in industry and resource efficiency, while in the agricultural sector, natural resource deployment efficiency leads to green economic growth. Practical policies such as supporting green technologies and innovations, transferring green technologies from advanced countries, imposing a carbon tax, and greening mechanization of the agricultural sector can be pursued by the governments of Central Asia.
Article
Medicine, General & Internal
Dan Wang, Zhulin Zhou, Bingjie Zhang, Bo Zhang, Hongfa Yang
Summary: This study compared the therapeutic effects of standard trauma craniectomy (STC) to conventional craniotomy in the treatment of traumatic multiple intracranial hematoma. The results indicated that STC had significant effects on recovery from consciousness disturbance at 1 week postoperatively but did not significantly improve recovery at 1 month postoperatively.
Article
Genetics & Heredity
Maria Isabel Alvarez-Mora, Laia Rodriguez-Revenga, Meritxell Jodar, Miriam Potrony, Aurora Sanchez, Celia Badenas, Josep Oriola, Jose Luis Villanueva-Canas, Esteban Munoz, Francesc Valldeoriola, Ana Camara, Yaroslau Compta, Mar Carreno, Maria Jose Marti, Raquel Sanchez-Valle, Irene Madrigal
Summary: Neurological disorders (ND) are diseases that affect the brain and the central and autonomic nervous systems. Next generation sequencing (NGS) is strongly recommended as a first-line test for diagnosing these disorders. Whole exome sequencing (WES) is the preferred technology for diagnosing monogenic ND. The implementation of WES has improved the diagnostic process and has a diagnostic rate of around 32% in ND.
Article
Neurosciences
Zeynep Balcikanli, Irem Culha, Pelin Dilsiz, Mehmet Serif Aydin, Nilay Ates, Mustafa Caglar Beker, Saltuk Bugra Baltaci, Halil Koc, Ahmet Yigitbasi, Mustafa Gundogar, Thorsten R. Doeppner, Dirk M. Hermann, Ertugrul Kilic
Summary: Spinal cord injury (SCI) can cause long-term neurological deficits, and the current treatments are ineffective. This study investigated the effects of lithium chloride (LiCl) on motor coordination recovery and neuroplasticity in mice with SCI. The results showed that LiCl can enhance motor coordination, reduce tissue atrophy, increase neuronal survival, and promote axonal regeneration.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
Fang Du, Jun-Wei Zheng, Yan-Bo Zhao, Kai Yang, Hu-Nian Li
Summary: This article reports a rare case of complete neurological recovery from severe nonexertional heat stroke in a 67-year-old woman. It highlights the importance of implementing comprehensive treatment as soon as heatstroke is diagnosed. Moreover, targeted temperature management, combination therapy with hemodialysis and hemoperfusion, and hyperbaric oxygen therapy may alleviate multiorgan failure and prevent neurological sequelae caused by heatstroke.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Review
Medicine, General & Internal
K. E. Ibebuike
Summary: The recent increase in violence and firearm attacks in society has led to an increase in civilian gunshot wounds (GSW) to the spine. There is controversy among spine surgeons regarding the management of GSW in the spine, with no clear recommendations for surgical intervention. We present a case of a 47-year-old female who suffered a GSW to the lumbar spine, resulting in immediate paraplegia. Surgical intervention, including laminectomy and duratomy with bullet removal, led to satisfactory neurological recovery.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2023)
Article
Geosciences, Multidisciplinary
Ian Metcalfe
Summary: The evolution of Tethyan ocean basins in Asia spans over 500 million years, involving opening and closure of oceans, collision of continental blocks, and formation of major orogenic belts. This complex geological history has shaped Asia's landscape and mineral resource distribution significantly.
Article
Multidisciplinary Sciences
Huw S. Groucutt, Tom S. White, Eleanor M. L. Scerri, Eric Andrieux, Richard Clark-Wilson, Paul S. Breeze, Simon J. Armitage, Mathew Stewart, Nick Drake, Julien Louys, Gilbert J. Price, Mathieu Duval, Ash Parton, Ian Candy, W. Christopher Carleton, Ceri Shipton, Richard P. Jennings, Muhammad Zahir, James Blinkhorn, Simon Blockley, Abdulaziz Al-Omari, Abdullah M. Alsharekh, Michael D. Petraglia
Summary: The research reveals distinct biological and cultural shifts between different hominin groups in Southwest Asia, with limited records from the vast arid region. Through studying sedimentary sequences, stone tools, and vertebrate fossils in the Nefud Desert, it is discovered that there were at least five early human expansions into the Arabian interior, coinciding with periods of reduced aridity. This suggests that ancient humans were sensitive to climate change and potentially migrated during times of decreased aridity.
Article
Agriculture, Dairy & Animal Science
Madalina Elena Henea, Eusebiu Viorel Sindilar, Liviu Catalin Burtan, Iuliana Mihai, Mariana Grecu, Alina Anton, Gheorghe Solcan
Summary: Spinal cord injuries in dogs are common and often caused by trauma or discal hernia. Physiotherapy and assisted gait devices can help paralyzed dogs develop spinal walking and improve their quality of life.
Article
Environmental Studies
Lingling Zhu
Summary: Asia's reliance on natural resource extraction poses significant challenges to its economic development and social inclusion. This study examines the correlation between economic growth, business structure, and resource use effectiveness using data from 2003 to 2019, as well as the moderating roles of education, financial freedom, and urbanization. The results show that the impact of natural resources on GDP growth in different regional economic blocs is nonlinear and variable. Trade pacts are found to reduce the influence of natural resources on the financial development of Asian countries. The study emphasizes the need for Asian countries to diversify their economies and create more jobs using the gains from natural resource extraction to achieve Sustainable Development Agenda Goals 8 and 10.