Cx43 and Mechanotransduction in Bone

High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation

(2014) Rafael Pacheco-Costa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling

(2013) Shane A. Lloyd et al.   BONE

Shifting Paradigms on the Role of Connexin43 in the Skeletal Response to Mechanical Load

(2013) Shane A Lloyd et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Deletion of a Single β-Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading

(2013) Behzad Javaheri et al.   JOURNAL OF BONE AND MINERAL RESEARCH

14-3-3  facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels

(2013) N. Batra et al.   JOURNAL OF CELL SCIENCE

Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice

(2013) Nicoletta Bivi et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The biochemistry and function of pannexin channels

(2012) Silvia Penuela et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Osteocyte control of osteoclastogenesis

(2012) Charles A. O'Brien et al.   BONE

Beyond gap junctions: Connexin43 and bone cell signaling

(2012) Lilian I. Plotkin et al.   BONE

Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading

(2012) Shane A Lloyd et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Connexin43 and Pannexin1 Channels in Osteoblasts: Who Is the “Hemichannel”?

(2012) Mia M. Thi et al.   JOURNAL OF MEMBRANE BIOLOGY

Enhanced Periosteal and Endocortical Responses to Axial Tibial Compression Loading in Conditional Connexin43 Deficient Mice

(2012) Susan K. Grimston et al.   PLoS One

Mechanical stress-activated integrin  5 1 induces opening of connexin 43 hemichannels

(2012) N. Batra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading

(2011) Xiaolin Tu et al.   BONE

Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis

(2011) Susan K Grimston et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for endocortical resorption and periosteal bone formation

(2011) Nicoletta Bivi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

(2011) Marcus Watkins et al.   MOLECULAR BIOLOGY OF THE CELL

Enhanced Osteoclastic Resorption and Responsiveness to Mechanical Load in Gap Junction Deficient Bone

(2011) Yue Zhang et al.   PLoS One

Development and characterization of a rapidly proliferating, well-differentiated cell line derived from normal adult human osteoblast-like cells transfected with SV40 large T antigen

(2010) Philip E. Keeting et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

(2010) Yukiko Kitase et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

(2010) S. Burra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connexins: a myriad of functions extending beyond assembly of gap junction channels

(2009) Hashem A Dbouk et al.   Cell Communication and Signaling

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Heterocellular interaction enhances recruitment of α and β-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells

(2008) Rabih S. Talhouk et al.   EXPERIMENTAL CELL RESEARCH

Adaptation of Connexin 43-Hemichannel Prostaglandin Release to Mechanical Loading

(2008) Arlene J. Siller-Jackson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuated Response to In Vivo Mechanical Loading in Mice With Conditional Osteoblast Ablation of the Connexin43 Gene (Gja1)

(2008) Susan K Grimston et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Functional Gap Junctions Between Osteocytic and Osteoblastic Cells

(2006) Clare E. Yellowley et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone-Resorbing Osteoclasts Contain Gap-Junctional Connexin-43

(2006) Joanna Ilvesaro et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Establishment of an Osteocyte-like Cell Line, MLO-Y4

(2006) Yoichi Kato et al.   JOURNAL OF BONE AND MINERAL RESEARCH