Article
Environmental Sciences
K. R. Deepak, Sooraj Mohan, P. Dinesha, Rajasekhar Balasubramanian
Summary: For the first time, activated hydrochar was prepared from orange peel waste using KOH for potential environmental applications. The impact of hydrothermal carbonization temperature on the CO2 adsorption capacity of the activated hydrochar was investigated. The results showed that the activated hydrochar had high microporosity and various functional groups, making it suitable for effective adsorption. The highest CO2 uptake was observed for the hydrochar produced at a temperature of 220°C.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Engineering, Environmental
Fangzhai Zhang, Yongzhen Peng, Zihui Liu, Yongwang Liu, Li Zhao
Summary: A novel fermentation-based double denitrification bioprocess successfully combined fermentation and denitrification, treating high ammonia wastewater efficiently with nitrogen removal and sludge reduction.
Article
Engineering, Environmental
Ya Xu, Guangyuan Yao, Rui Xiang, Yuqiang Liu, Qifei Huang
Summary: Due to the complexity of industrial solid waste, heavy metals and organics can be enriched in leachate, leading to clogging of the leachate collection system (LCS) and increased leakage risk. This study investigated the clogging process of LCS in industrial solid waste landfills (ISWLs) through laboratory experiments and model simulations. The results showed that the LCS of ISWLs in China faces severe clogging challenges, with the rate of clogging being inversely proportional to the rate of leachate production. Infiltration conditions were found to be the main influencing factor, with accelerated infiltration resulting in shortened clogging time.
Article
Engineering, Environmental
Emine Can-Guven, Senem Yazici Guvenc, Gamze Varank
Summary: This study investigated a sequential treatment of landfill leachate including coagulation and binary oxidation processes. The research optimized the chemical coagulation process and examined the factors affecting the binary oxidation process to achieve high removal efficiencies. The results showed that the binary processes were more effective than single processes, reaching significant removal efficiencies under optimal conditions.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Environmental Sciences
Siying Sun, Jiabao Ren, Jiale Liu, Liang Rong, Hangli Wang, Yeyuan Xiao, Faqian Sun, Rongwei Mei, Chongjun Chen, Xiaomei Su
Summary: The study found that pyrite-activated persulfate oxidation efficiently removed organic matter from the effluent of a biological landfill leachate treatment system, and subsequent denitrification was also successful. With the optimal parameters, a COD removal efficiency of about 45% and a nitrate removal rate of around 108 mg L-1 d(-1) were achieved.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Water Resources
Ibrahim Metin Hasdemir, Emre Yilmazoglu, Senem Gungor, Belma Hasdemir
Summary: In this study, activated carbon was prepared using hazelnut shells, orange peel, and melon seeds as raw materials. The adsorption efficiencies of the produced activated carbons were evaluated and compared with a commercial activated carbon. The results showed that the activated carbons derived from hazelnut shells and orange peel exhibited higher adsorption efficiencies.
APPLIED WATER SCIENCE
(2022)
Article
Agricultural Engineering
Jarungwit Boonnorat, Ryo Honda, Pornpan Panichnumsin, Nimaradee Boonapatcharoen, Nawamin Yenjam, Chananya Krasaesueb, Manyapron Wachirawat, Sestapong Seemuang-on, Rumpa Jutakanoke, Jantima Teeka, Sivakorn Angthong, Pradthana Prachanurak
Summary: This research investigates the efficiency and greenhouse gas emissions of non-floating and floating bed AS systems treating landfill leachate, finding that the floating bed AS system maintains stable treatment efficiency due to an abundance of effective bacteria. The study shows that CO2 emissions are positively correlated with organic loading and inversely correlated with HRT, while CH4 emissions are positively correlated with HRT, and N2O emissions are mainly linked to nitrogen loading.
BIORESOURCE TECHNOLOGY
(2021)
Article
Engineering, Environmental
Jianchao Wang, Dongbei Yue, Mingchun Li, Huijing Wang, Jianbing Wang, Chunrong Wang, Huijiao Wang
Summary: This study evaluated the application of carbon nitride nanosheets (CN-Ns) for adsorption of humic substances and leachate nanofiltration concentrates. The results showed that increasing the thermal oxidation temperature improved the adsorption performance of CN-Ns and their affinity for humic substances. This finding is important for the treatment of landfill leachate.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Guangzhi Wang, Simin Zhou, Dongdong Wang, Lina Feng, Yuanyuan Xu, Likun Huang
Summary: This study compared the effectiveness of different UV/PDS systems in treating landfill leachate and found that the medium-pressure built-in device and segmented dosing process could achieve better treatment results.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Pharmacology & Pharmacy
Daniela Iannazzo, Consuelo Celesti, Claudia Espro, Angelo Ferlazzo, Salvatore Giofre, Mario Scuderi, Silvia Scalese, Bartolo Gabriele, Raffaella Mancuso, Ida Ziccarelli, Giuseppa Visalli, Angela Di Pietro
Summary: Cancer-targeted drug delivery systems based on carbon nanostructures have shown great promise in cancer therapy due to their ability to selectively recognize specific receptors overexpressed in cancer cells. In this study, nanobiochar with graphene structure was synthesized from orange peels using a green method, and evaluated as a nanoplatform for cancer therapy. Conjugation of NBC with different targeting ligands showed effective internalization of drugs and anticancer activity against A549 cells.
Article
Chemistry, Inorganic & Nuclear
K. M. Ajay, M. N. Dinesh, Gopalakrishna Byatarayappa, M. G. Radhika, N. Kathyayini, H. Vijeth
Summary: The comparative study of electrode materials for supercapacitors showed that the Polyaniline-OPAC nanocomposite electrode exhibited higher specific capacitance and better cycling stability compared to the OPAC electrode.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Green & Sustainable Science & Technology
Guandong Su, Claire Chan, Jianzhong He
Summary: The study successfully increased the butanol production from rice waste with the addition of orange peel as a cofactor additive, leading to a shortened fermentation period. By mixing orange peel, a significant reduction in production cost was achieved, making it an effective strategy for sustainable food waste management.
Article
Chemistry, Multidisciplinary
Vivek Laishram, Potsangbam Albino Kumar
Summary: This study focuses on the adsorption of COD organic matter from pretreated landfill leachate using H3PO4 treated activated carbon derived from Parkia speciosa (Petai) pods (PPAC). The adsorbent was analyzed for morphology and surface characteristics, and the impact of various factors on the adsorption process was considered. The performance of PPAC was compared with other reported adsorbents.
Article
Environmental Sciences
Meng Gao, Siqi Li, Huijing Zou, Fushan Wen, Anrong Cai, Ruilin Zhu, Wenjing Tian, Dezhi Shi, Hongxiang Chai, Li Gu
Summary: Anaerobic digestion (AD) is a sustainable method for recovering energy from organic wastes, but the efficiency for waste activated sludge (WAS) is limited due to WAS hydrolysis constraints. This study proposes a strategy to treat WAS and landfill leachate simultaneously, aiming to enhance WAS hydrolysis and organic conversion to methane. The effects of landfill leachate on the different stages of AD of WAS were investigated, showing that appropriate amounts of leachate can promote solubilization, hydrolysis, and acidogenesis, but not methanogenesis. Mechanism studies revealed the beneficial effects of humic acid in leachate on hydrolysis and acidogenesis, and the dose-dependent effects of heavy metals on the AD process. Additionally, microbial community analysis showed an increase in microbes responsible for hydrolysis and acidogenesis with the presence of landfill leachate.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2021)
Article
Engineering, Environmental
Masapogu Yellappa, Omprakash Sarkar, Y. V. Rami Reddy, S. Venkata Mohan
Summary: This study aimed to achieve sustainable treatment of municipal landfill leachate (MLL) and resource recovery by integrating acidogenesis and bioelectrogenesis. The acidogenic fermentation process converted more than 60% of MLL COD to biohydrogen and volatile fatty acids (VFAs). By introducing the leftover COD into a bio-electrochemical treatment system, the modified composite electrode in the BET1 configuration showed significant improvement in leachate treatment, with a COD removal of 71.21% and a power density of 35 mW/m2.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2023)
Review
Biotechnology & Applied Microbiology
Weiqi Wang, Yuting Yu, Yilan Jin, Xiao Liu, Min Shang, Xiaohua Zheng, Tingting Liu, Zhigang Xie
Summary: This review article highlights the unique structural properties of ultrathin metal-organic framework nanosheets and their advantages in technological applications. It summarizes the design strategies and fabrication methods, and presents the recent advancements in the bioapplications of two-dimensional metal-organic frameworks and future opportunities.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Hongxin Liu, Zhigang Xie, Min Zheng
Summary: Chiral nanovaccines have potential applications in cancer immunotherapy by carrying antigens and inducing immune responses, showing inhibitory effects on melanoma growth.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Yite Li, Liqian Liu, Tian Meng, Lei Wang, Zhigang Xie
Summary: An ionic ZIF-8@iCOF nanocomposite was designed as a sunlight-driven photocatalytic filter, which achieved improved visible light absorption and enhanced ROS generation, resulting in antibacterial efficiency of 99.99999%. Furthermore, the combination of the material with a commercial polymer formed fibrous membranes with high interception efficiency, good biocompatibility, and strong bacteria elimination under sunlight conditions.
Article
Materials Science, Biomaterials
Yawei Li, Wei Zhang, Naiyuan Shi, Wenqing Li, Junxia Bi, Xianmin Feng, Nianqiu Shi, Wenhe Zhu, Zhigang Xie
Summary: By utilizing the self-assembly of DHA, carrier-free nanoparticles with high drug encapsulation efficiency and on-demand drug release behavior were synthesized. These DHA nanodrugs exhibited superior therapeutic efficacy in cancer treatment in both in vitro and in vivo experiments, with the p53 signaling pathway playing a crucial role. This work provides theoretical support for developing pure nanodrugs via self-assembly and for the clinical usage of DHA.
BIOMATERIALS SCIENCE
(2023)
Article
Materials Science, Biomaterials
Chengjian Mou, Xinyuan Wang, Yanchao Liu, Zhigang Xie, Min Zheng
Summary: Developing highly effective antibacterial films for wound healing is a challenge. Homogeneous and flexible CDs-PVA composite films were constructed by doping CDs into PVA. PVA(5) and PVA(8) showed excellent antibacterial performance against both Gram-negative and Gram-positive bacteria, and could be easily processed into band-aid type dressings for wound healing.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Dengyuan Hao, Qian Meng, Chaonan Li, Shaojin Lu, Xiujuan Xiang, Qing Pei, Xiabin Jing, Zhigang Xie
Summary: Tuning the content of copper is highly significant for cancer and neurodegenerative disease treatment. A copper-chelating PTX prodrug was synthesized and could form stable nanoparticles in aqueous media. After internalization by tumor cells, the nanoparticles responded to redox-active species and released PTX, resulting in an enhanced therapeutic outcome for breast cancer with minimal systemic toxicity. This work provides insight into combining metabolic regulation and chemotherapy for malignant tumors.
Article
Chemistry, Multidisciplinary
Hongxin Liu, Zhigang Xie, Min Zheng
Summary: Cancer immunotherapy is a popular area of research, and carbon dots have shown potential as nanovectors to enhance its efficacy.
Review
Pharmacology & Pharmacy
Qing Pei, Bowen Jiang, Dengyuan Hao, Zhigang Xie
Summary: Chemotherapy plays a critical role in cancer treatment, especially for advanced and metastatic tumors. However, the therapeutic effect of Paclitaxel-based formulations is limited by off-target toxicity and drug resistance. Self-assembled PTX nanoparticles have shown promise in enhancing therapeutic index. This study summarizes the self-assembly strategy of PTX nanodrugs and outlines the advancements in tumor therapy, including mono chemotherapy, combination therapy, and theranostics.
ACTA PHARMACEUTICA SINICA B
(2023)
Article
Nanoscience & Nanotechnology
Min Zhao, Dengyuan Hao, Qihang Wu, Yite Li, Qing Pei, Tingting Sun, Ke Wang, Zhigang Xie
Summary: Lung cancer is the leading cause of cancer deaths worldwide. This study proposes a combination therapy of photodynamic therapy (PDT) and immune checkpoint inhibitors (ICIs) for lung cancer. The designed porphyrin cholesterol conjugates showed enhanced efficacy in reshaping the tumor immune microenvironment and suppressing tumor growth.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Tingting Sun, Jiaxiang Guo, Hui Wen, Qing Pei, Qihang Wu, Dengyuan Hao, Chuandong Dou, Zhigang Xie
Summary: This study reports the photothermal conversion behaviors of a boron-containing organic diradicaloid (BOD), which can assemble with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) to form rodlike nanoparticles (BOD NPs). These BOD NPs show high photothermal conversion capability and stability, and possess morphological superiority for effective photothermal therapy of tumors. This work demonstrates the promise of organic diradicaloids as efficient photothermal agents for biomedical applications.
Article
Materials Science, Biomaterials
Wentao Lei, Qihang Wu, Hui Wen, Yulin Wang, Wenhai Lin, Tingting Sun, Zhigang Xie
Summary: Amino acids are fundamental building blocks of life in biological systems, and their modification can add interesting properties to key molecules. In this study, BDP was modified with l-aspartic acid (Asp) and d-Asp to produce BDP-LAsp and BDP-DAsp, respectively. The synthesized BDPs can self-assemble into uniform nanoparticles (NPs) due to the hydrophilicity of Asp. We discovered that BDP-LAsp NPs exhibited higher photodynamic therapeutic efficacy against cancer cells and bacteria compared to BDP-DAsp NPs. This presents a simple design strategy for modifying photosensitizers in the field of biomedicine.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Wei Zhang, Wenhai Lin, Zhensheng Li, Tingting Sun, Zhigang Xie
Summary: Photothermal therapy (PTT) is an effective tumor therapeutic method, but the overexpression of heat shock proteins (HSPs) and the self-repair mechanism of malignant tumors may limit its efficacy. A nanoplatform (IBDDP&GOx NPs) integrating PTT, starvation therapy, and oxidation therapy was developed using a conjugated polymer (IBDDP) and glucose oxidase (GOx). This nanoplatform effectively combines the photothermal properties of IBDDP and the biological catalytic activity of GOx, resulting in enhanced inhibitory effects on tumor cell survival and proliferation.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Materials Science, Biomaterials
Huafeng Geng, Wenhai Lin, Junbao Liu, Qing Pei, Zhigang Xie
Summary: Phototheranostics, integrating optical imaging and phototherapy, has received widespread attention. Achieving nanophototherapeutics with near infrared (NIR)-light synchronously triggered photodynamic therapy (PDT) and photothermal therapy (PTT) is challenging. In this study, a multifunctional theranostic nanoplatform was developed by co-assembling NIR boron dipyrromethene (BODIPY) with a cooperative D-pi-A structure of a thiophene-BODIPY core and benzene-diethylamino, and a choline phosphate lipid. The resulting nanoparticles exhibited desirable NIR absorption, uniform spherical morphology, and good colloidal stability. The elaborate molecular design and supramolecular assembly endowed these nanoparticles with desirable PDT and PTT activities.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Review
Materials Science, Multidisciplinary
Yanting Shi, Yutao Zou, M. Shahnawaz Khan, Mengge Zhang, Jiang Yan, Xiaohua Zheng, Weiqi Wang, Zhigang Xie
Summary: Metal-organic frameworks (MOFs) are highly ordered self-assembled structures with large surface areas, nanoporosity, and tunable size and shape, making them ideal candidates for sensor applications. This review explores the structural features of MOFs for biological sensing and the MOF-analyte interaction, as well as the state-of-the-art progress in MOF-based sensors for healthcare, food safety, environmental monitoring, and pharmaceutics. The review also discusses the possible applications of MOF-based materials in identifying high performance and detecting food freshness, gas leakage, and medical diagnostics, and highlights the current limitations in sensing performance.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Materials Science, Biomaterials
Hui Wen, Qihang Wu, Liqian Liu, Yite Li, Tingting Sun, Zhigang Xie
Summary: The therapeutic effects of photodynamic antibacterial agents can be influenced by the structures of photosensitizers. This study designed and tested 4 BODIPYs with different functional groups and found that the BODIPY with phenylboronic acid (PBA) group exhibited potent activity against planktonic Staphylococcus aureus, while the BODIPY with pyridine (Py) cations or both PBA group and Py cations significantly inhibited the growth of both S. aureus and Escherichia coli. In addition, the BODIPY with Py cations could eliminate mature S. aureus biofilms and promote wound healing. This research provides new insights for the rational design of photodynamic antibacterial materials.
BIOMATERIALS SCIENCE
(2023)
