期刊
INTERNATIONAL JOURNAL OF GENOMICS
卷 2014, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2014/639687
关键词
-
资金
- earmarked fund for Modern Agro-Industry Technology Research System [CARS-46-17]
- National Key Technology RD Program [2012BAD25B04]
- Guangdong Natural Science Foundation [10151038001000004]
Grass carp (Ctenopharyngodon idellus) is one of the most important freshwater fish that is native to China, and crisp grass carp is a kind of high value-added fishes which have higher muscle firmness. To investigate biological functions and possible signal transduction pathways that address muscle firmness increase of crisp grass carp, microarray analysis of 14,900 transcripts was performed. Compared with grass carp, 127 genes were upregulated and 114 genes were downregulated in crisp grass carp. Gene ontology (GO) analysis revealed 30 GOs of differentially expressed genes in crisp grass carp. And strong correlation with muscle firmness increase of crisp grass carp was found for these genes from differentiation of muscle fibers and deposition of ECM, and also glycolysis/gluconeogenesis pathway and calcium metabolism may contribute to muscle firmness increase. In addition, a number of genes with unknown functions may be related to muscle firmness, and these genes are still further explored. Overall, these results had been demonstrated to play important roles in clarifying the molecular mechanism of muscle firmness increase in crisp grass carp.
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