Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Leptin Activates Human B Cells to Secrete TNF-α, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 Signaling Pathway

(2011) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors

(2010) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Impaired Functions of Peripheral Blood Monocyte Subpopulations in Aged Humans

(2010) Joseph Nyugen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Leptin Signaling: A Key Pathway in Immune Responses

(2009) Claudio Procaccini et al.   Current Signal Transduction Therapy

Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells

(2008) Jingchun Gao et al.   CANCER SCIENCE