Article
Respiratory System
Jerome Le Pavec, Dominique Valeyre, Pierre Gazengel, Are M. Holm, Hans Henrik Schultz, Michael Perch, Aurelie Le Borgne, Martine Reynaud-Gaubert, Christiane Knoop, Laurent Godinas, Sandrine Hirschi, Vincent Bunel, Rosalia Laporta, Sergio Harari, Elodie Blanchard, Jesper M. Magnusson, Adrien Tissot, Clement Picard, Laurent Savale, Jean-Francois Bernaudin, Pierre-Yves Brillet, Hilario Nunes, Marc Humbert, Elie Fadel, Jens Gottlieb
Summary: This study retrospectively reviewed data from 112 patients with pulmonary sarcoidosis who underwent lung or heart-lung transplantation, finding that post-transplant survival rates were similar to those with other indications for lung transplantation. Older age and extensive pre-operative lung fibrosis were the main factors associated with worse survival.
EUROPEAN RESPIRATORY JOURNAL
(2021)
Article
Oncology
Kun-yin Qiu, Xiong-yu Liao, Yang Li, Ke Huang, Hong-gui Xu, Jian-pei Fang, Dun-hua Zhou
Summary: This study compared the outcome and prognostic factors between inv(16) and t(8;21) in AML. It was found that patients with t(8;21) had lower overall survival and lower relapse rate. Additionally, pediatric AML patients receiving more cytarabine courses had lower relapse rate. For inv(16) patients not receiving GO treatment, the overall survival was lower and the relapse rate was higher compared to t(8;21) patients. However, inv(16) and t(8;21) patients receiving GO treatment had comparable outcomes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Fei Wu, Haitao Sun, Changwu Zhou, Peng Huang, Yuyao Xiao, Chun Yang, Mengsu Zeng
Summary: This study evaluated whether radiological similarity and clinicopathological factors determine the prognosis in bifocal hepatocellular carcinoma (bHCC) stratified by the Milan criteria. The study found that the radiological similarity of bHCC lesions is associated with long-term prognosis, in addition to other factors.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Christian Steffen Mayer, Lukas Reznicek, Isabella Diana Baur, Ramin Khoramnia
Summary: The study found that patients with posterior segment involvement in open globe injuries had worse postoperative visual acuity, with good prognostic factors being good initial CDVA and injuries affecting only zones I and II.
Article
Oncology
Nevine F. Shafik, Amira D. Darwish, Rasha Mahmoud Allam, Ghada M. Elsayed
Summary: FLT3-ITD mutations, with variable allelic ratios and sizes, significantly impact the prognosis of AML patients. High FLT3-ITD AR and AF are associated with lower overall survival, while NPM1 mutation does not have a favorable impact on low-level FLT3-ITD cases.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
(2021)
Article
Oncology
Ching-Yu Cheng, Heng-Cheng Hsu, Yi-Jou Tai, Ying-Cheng Chiang, Yu-Li Chen, Wen-Fang Cheng
Summary: The study found that the prognosis of unexpected ovarian cancer is independent of the primary surgical procedure. Prognostic factors included the FIGO stage, histological type, tumor grade, and timing of surgery and chemotherapy. Comprehensive staging surgery should be performed promptly after diagnosis to improve outcomes.
Article
Oncology
Jerold Loh, Jiaxuan Wu, Jenny Chieng, Aurora Chan, Wei-Peng Yong, Raghav Sundar, Soo-Chin Lee, Andrea Wong, Joline S. J. Lim, David S. P. Tan, Ross Soo, Boon-Cher Goh, Bee-Choo Tai, Cheng E. Chee
Summary: Patient selection is crucial in Phase I studies, particularly in heavily pre-treated patients where prognosis estimation is challenging. Existing prognostic models like the Royal Marsden Hospital (RMH) score or the neutrophil-lymphocyte ratio (NLR) have not been validated in current novel therapies or in the Asian Phase I population.
BRITISH JOURNAL OF CANCER
(2023)
Article
Otorhinolaryngology
Katharina Geissler, Elisabeth Urban, Gerd F. Volk, Carsten M. Klingner, Otto W. Witte, Orlando Guntinas-Lichius
Summary: Infectious causes such as Varicella Zoster Virus reactivation and Lyme disease have the best probability for complete recovery in patients with non-idiopathic peripheral facial palsy, while post-surgery FP has a worse prognosis. Patients with traumatic FP have a higher proportion of complete recovery.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Oncology
Zibin Zhang, Xiaojun Pang, Yuyu Wei, Qingping Lv, Xuhong Jin, Huai Chen
Summary: This study aimed to identify the independent prognostic factors influencing the overall survival prognosis of intracranial subependymoma and construct a prognostic model for predicting survival time. The results showed that age and sex were independent prognostic variables for overall survival in intracranial subependymoma.
FRONTIERS IN ONCOLOGY
(2022)
Article
Hematology
Linus Angenendt, Marius Woeste, Jan-Henrik Mikesch, Maria Francisca Arteaga, Adrian Angenendt, Sarah Sandmann, Wolfgang E. Berdel, Georg Lenz, Martin Dugas, Soheil Meshinchi, Christoph Schliemann, Claudia Roessig
Summary: High expression of CALCRL is independently associated with event-free survival, overall survival, and incidence of relapse in pediatric patients with AML, indicating its potential as a therapeutic target for this population.
Article
Oncology
Tao Xia, Xiaosan Wu, Yiping Mou, Yunyun Xu, Yucheng Zhou, Chao Lu, Qicong Zhu, Weiwei Jin, Yuan Chen
Summary: Pancreatobiliary-type ampullary tumors were associated with poor survival. Serum CA 19-9 in the intestinal-type and CEA in the pancreatobiliary-type were significantly associated with poor survival. Adjuvant chemotherapy could not predict the survival of AAV patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Jose F. Carrillo, Christian Cruz-Romero, Alejandro Aviles-Salas, Liliana C. Carrillo, Margarita C. Ramirez-Ortega, Roberto Herrera-Goepfert, Rafael Vazquez-Romo, Gabriela Figueroa-Gonzalez, Javier Altamirano-Garcia, Luis F. Onate-Ocana
Summary: This study defines the prognostic role of LKB-1 expression in patients with squamous cell carcinoma of the oral cavity (SCCOC) and proposes a predictive model that complements the TNM staging system. The model allows for prediction of recurrence risk and survival rates, and defines prognostic groups for patients.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Waseem Masalha, Dieter Henrik Heiland, Christine Steiert, Marie T. Krueger, Daniel Schnell, Christian Scheiwe, Oliver Schnell, Anca-L Grosu, Juergen Beck, Juergen Grauvogel
Summary: The study concluded that gross total resection is the most important prognostic factor for lower recurrence rates and longer progression-free survival in patients with spheno-orbital meningioma. Tumors invading the cavernous sinus and intraconal region showed significantly worse PFS compared to other locations. Postoperative high-precision radiotherapy did not lead to significantly better PFS outcomes.
FRONTIERS IN ONCOLOGY
(2021)
Review
Economics
Fabio Efficaee, Gary S. Collins, Francesco Cottone, Johannes M. Giesinger, Kathrin Sommer, Amelie Anota, Michael Maia Schlussel, Paola Fazi, Marco Vignetti
Summary: This systematic review found that PROs are statistically significant predictors of survival in cancer patients, with the EORTC QLQ-C30 questionnaire playing a particularly important role in predicting overall survival. Further research is needed to develop prognostic tools based on this evidence to assist in clinical decision-making.
Article
Oncology
Mehran B. Yusuf, Jeremy Gaskins, Abbas Rattani, Grant McKenzie, Steven Mandish, Weston Wall, Alyssa Farley, Paul Tennant, Jeffrey Bumpous, Neal Dunlap
Summary: Background immunosuppression is not currently considered in Merkel cell carcinoma staging. An analysis of the National Cancer Database investigated immune status as an independent predictor of overall survival for MCC patients. Immune status and the etiology of IS may be important prognostic factors in future staging systems for MCC.
ANNALS OF SURGICAL ONCOLOGY
(2021)