SHROOM3 is a novel candidate for heterotaxy identified by whole exome sequencing

Exome Sequencing Identifies Truncating Mutations in Human SERPINF1 in Autosomal-Recessive Osteogenesis Imperfecta

(2011) Jutta Becker et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Geminin is required for left–right patterning through regulating Kupffer’s vesicle formation and ciliogenesis in zebrafish

(2011) Sizhou Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

(2011) Timothy F. Plageman et al.   DEVELOPMENTAL BIOLOGY

Loss of Cited2 causes congenital heart disease by perturbing left–right patterning of the body axis

(2011) Kylie Lopes Floro et al.   HUMAN MOLECULAR GENETICS

Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13

(2011) Minal Çalışkan et al.   HUMAN MOLECULAR GENETICS

Rapid identification of mutations in GJC2 in primary lymphoedema using whole exome sequencing combined with linkage analysis with delineation of the phenotype

(2011) P. Ostergaard et al.   JOURNAL OF MEDICAL GENETICS

Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning

(2011) K. A. Fakhro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole Exome Sequencing and Homozygosity Mapping Identify Mutation in the Cell Polarity Protein GPSM2 as the Cause of Nonsyndromic Hearing Loss DFNB82

(2010) Tom Walsh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

(2010) T. F. Plageman et al.   DEVELOPMENT

Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut

(2010) M.-I Chung et al.   DEVELOPMENT

The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer's vesicle in zebrafish

(2010) G. Wang et al.   DEVELOPMENT

Zebrafish Nkd1 promotes Dvl degradation and is required for left–right patterning

(2010) Igor Schneider et al.   DEVELOPMENTAL BIOLOGY

Far from solved: A perspective on what we know about early mechanisms of left-right asymmetry

(2010) Laura N. Vandenberg et al.   DEVELOPMENTAL DYNAMICS

Planar polarization of node cells determines the rotational axis of node cilia

(2010) Masakazu Hashimoto et al.   NATURE CELL BIOLOGY

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

(2010) Edgar A Otto et al.   NATURE GENETICS

Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome

(2010) Peter M Krawitz et al.   NATURE GENETICS

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis

(2010) Dragana Antic et al.   PLoS One

Normal Bias in the Direction of Fetal Rotation Depends on Blastomere Composition during Early Cleavage in the Mouse

(2010) Richard L. Gardner   PLoS One

Ciliary biology: Understanding the cellular and genetic basis of human ciliopathies

(2009) Magdalena Cardenas-Rodriguez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Disorders of left-right asymmetry: Heterotaxy and situs inversus

(2009) Mardi J. Sutherland et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Recurrence of Congenital Heart Defects in Families

(2009) Nina Øyen et al.   CIRCULATION

Chiral blastomere arrangement dictates zygotic left–right asymmetry pathway in snails

(2009) Reiko Kuroda et al.   NATURE

Exome sequencing identifies the cause of a mendelian disorder

(2009) Sarah B Ng et al.   NATURE GENETICS

Reduced NODAL Signaling Strength via Mutation of Several Pathway Members Including FOXH1 Is Linked to Human Heart Defects and Holoprosencephaly

(2008) Erich Roessler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT

The Chirality of Gut Rotation Derives from Left-Right Asymmetric Changes in the Architecture of the Dorsal Mesentery

(2008) Nicole M. Davis et al.   DEVELOPMENTAL CELL

What's left in asymmetry?

(2008) Sherry Aw et al.   DEVELOPMENTAL DYNAMICS

Perspectives and open problems in the early phases of left–right patterning

(2008) Laura N. Vandenberg et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left–right asymmetry

(2007) Sherry Aw et al.   MECHANISMS OF DEVELOPMENT