Review
Biochemistry & Molecular Biology
Muhammad Zubair, Zhaojun Li, Rongsheng Zhu, Jiancai Wang, Xinghua Liu, Xiayan Liu
Summary: Antibiotics are given to livestock at subtherapeutic levels to promote growth, but their slow degradation in manure leads to high concentrations that can inhibit bacterial activity. Livestock excretes antibiotics via feces and urine, resulting in the accumulation of antibiotic-resistant bacteria and genes in manure. Anaerobic digestion (AD) manure treatment technologies, especially thermophilic AD, can effectively reduce antibiotic resistance genes, making them crucial for waste management to mitigate antibiotic resistance.
Article
Environmental Sciences
Fang-Zhou Gao, Liang-Ying He, Li-Xin Hu, Jun Chen, Yuan-Yuan Yang, Lu-Xi He, Hong Bai, You-Sheng Liu, Jian-Liang Zhao, Guang-Guo Ying
Summary: Emission of antibiotics into riverine environments affects aquatic ecosystem functions and leads to the development of antibiotic resistance. The study found that river sections close to urban and livestock areas contain more antibiotics and antibiotic resistance genes (ARGs). Antibiotic concentration is correlated with ARG abundance in the water, indicating antibiotics play a critical role in ARG spread. Some antibiotics pose ecotoxicological risks to aquatic organisms and sediment. The Nanliujiang river with intensive livestock activities is contaminated by antibiotics and ARGs and faces high ecotoxicological and resistance selection risks.
ENVIRONMENTAL POLLUTION
(2022)
Review
Biotechnology & Applied Microbiology
Gisele Rodrigues, Mariana Rocha Maximiano, Octavio Luiz Franco
Summary: This review discusses the use of antibiotic growth promoters in livestock and the negative consequences, proposing the use of antimicrobial peptides as an alternative approach to control antimicrobial resistance.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
Sirinthrar Wandee, Rathborey Chan, Wilai Chiemchaisri, Chart Chiemchaisri
Summary: The study found that in open pig farming systems, there is a high level of E. coli populations, antibiotic contamination in supplied water, and additional antibiotic usage, such as neomycin or colistin. Additionally, an increased occurrence of ARE was found in anaerobic digestion and waste stabilisation ponds, but they were not well correlated with their residual antibiotic concentrations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Physical
Tanya Verma, Anchal Aggarwal, Shikha Singh, Sumit Sharma, Saurabh Jyoti Sarma
Summary: The discovery of antibiotics has significantly improved the treatment of infectious diseases and increased human life expectancy. However, the development of antibiotic resistance by microorganisms remains a major concern. The sensitivity and resistivity of bacteria play a crucial role in the effectiveness of antibiotics.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Microbiology
Linsey Donner, Zachery R. Staley, Jonathan Petali, Jodi Sangster, Xu Li, Wayne Mathews, Daniel Snow, Adina Howe, Michelle Soupir, Shannon Bartelt-Hunt
Summary: One Health field-based approaches are needed to study the linkage between antibiotics and bacterial antibiotic resistance genes (ARGs) in the environment. Water samples from two Nebraska watersheds influenced by wastewater effluent and agricultural runoff were tested, and ARGs associated with the presence of antibiotics were detected in Gram-negative bacteria through whole-genome sequencing and antimicrobial susceptibility testing.
MICROBIOLOGY SPECTRUM
(2022)
Article
Infectious Diseases
Nazym Iskakova, Zaituna Khismetova, Dana Suleymenova, Zhanat Kozhekenova, Zaituna Khamidullina, Umutzhan Samarova, Natalya Glushkova, Yuliya Semenova
Summary: The survey reveals low awareness of antibiotic use and resistance among the adult population of Kazakhstan, highlighting the need for educational campaigns to improve knowledge.
Article
Oncology
Amila K. Nanayakkara, Helen W. Boucher, Vance G. Fowler, Amanda Jezek, Kevin Outterson, David E. Greenberg
Summary: Antibiotic resistance poses a significant threat to the success of cancer therapy, necessitating measures to control its emergence. Establishing a specialized monitoring system and finding better ways to predict, prevent, and treat antibiotic-resistant infections will have a positive impact on the care of cancer patients.
CA-A CANCER JOURNAL FOR CLINICIANS
(2021)
Article
Agriculture, Dairy & Animal Science
Adar Cohen, Liat Poupko, Hillary A. Craddock, Yair Motro, Boris Khalfin, Amit Zelinger, Sharon Tirosh-Levy, Shlomo E. Blum, Amir Steinman, Jacob Moran-Gilad
Summary: Extended-spectrum beta-lactamases (ESBLs) are a growing public health threat, and one key human exposure point is through livestock and the food supply. This study observed that heifers from farms feeding calves with pooled colostrum had higher rates of ESBL carriage, and several genera of bacteria also differed between ESBL carriers and noncarriers.
Article
Infectious Diseases
Nan Christine Wang
Summary: The study revealed a high prevalence of caregivers giving non-prescribed antibiotics to children before medical visits in China. Caregivers with older children and lower education levels were more likely to self-medicate with antibiotics. Caregivers in tier 2 urban districts were most prone to administering non-prescribed antibiotics before medical visits.
Review
Microbiology
Ali Khalid, Ruby C. Y. Lin, Jonathan R. Iredell
Summary: Approximately 10% of global health research is dedicated to addressing 90% of the global disease burden, often overlooking diseases prevalent in low-income countries. Antibiotic resistant bacterial infections have significant impacts on healthcare, food security, and the socio-economic fabric of developing countries. Phage therapy, sourced and processed locally, presents an attractive and feasible option for treating infections in developing countries amid the global antibiotic resistance crisis.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Environmental Sciences
Zhou Chen, Yanzeng Li, Chengsong Ye, Xin He, Shenghua Zhang
Summary: The study found that aerobic co-composting of food waste with sewage sludge can effectively remove antibiotics and ARGs, with low efficiency in removing sulfonamides. 16S rRNA sequencing revealed changes in microbial communities during composting, while quantitative PCR experiments showed that antibiotic concentrations can affect the abundance of ARGs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Green & Sustainable Science & Technology
Hossein Azadi, Fatemeh Taheri, Samane Ghazali, Saghi Movahhed Moghaddam, Narges Siamian, Imaneh Goli, Shahla Choobchian, Maryam Pour, Ahsen Isik Ozguven, Kristina Janeckova, Petr Sklenicka, Frank Witlox
Summary: This study investigates the environmental, social, and economic consequences of genetically modified (GM) crops at the farm level in developing countries through a meta-analysis. The results show that genetic modification technology can enhance the socio-economic and environmental efficiency of farmers in developing countries. However, the long-term sustainability of genetic modification production is reduced.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Environmental Sciences
Anna Navarro, Isabella Sanseverino, Francesca Cappelli, Armin Lahm, Magdalena Niegowska, Marco Fabbri, Valentina Paracchini, Mauro Petrillo, Helle Skejo, Sara Valsecchi, Rosalba Pedraccini, Stefano Guglielmetti, Stefano Frattini, Gabriella Villani, Teresa Lettieri
Summary: This study aimed to investigate the bacterial diversity and background level of antibiotic resistance in two freshwater ecosystems with low anthropogenic impact. The results showed higher bacterial load in the Tiber River compared to the Variola River. The presence of resistant bacteria was detected, especially in the Tiber River, which showed resistance to all antibiotics tested, while the Variola River showed variable resistance to two or more antibiotics. The dominant resistance gene identified was blaTEM, conferring resistance to f3-lactam antibiotics, present in 58% of isolates, compared to only 9% for mefA/E conferring resistance to macrolides. f3-lactam resistance was detected in isolates showing resistance to additional antibiotics such as macrolides, aminoglycosides, and tetracyclines.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Microbiology
Sabin Poudel, Tianmin Li, Saijuan Chen, Xue Zhang, Wen-Hsing Cheng, Anuraj T. Sukumaran, Aaron S. Kiess, Li Zhang
Summary: This study found that the prevalence of Campylobacter was higher in retail meat samples than in environmental samples from farms, and there was no difference in Campylobacter prevalence between conventional and no-antibiotics-ever (NAE) retail chicken. The predominant virulence genes in Campylobacter isolates were gyrA and tet(O), while these genes were not detected in Campylobacter isolated from litter samples.
MICROBIOLOGY SPECTRUM
(2022)
Article
Immunology
Peter C. Collignon, John M. Conly, Antoine Andremont, Scott A. McEwen, Awa Aidara-Kane
CLINICAL INFECTIOUS DISEASES
(2016)
Review
Medicine, General & Internal
Peter J. Collignon, Gary D. Lum, Jennifer M. B. Robson
MEDICAL JOURNAL OF AUSTRALIA
(2016)
Article
Microbiology
Belinda Vangchhia, Michaela D. J. Blyton, Peter Collignon, Karina Kennedy, David M. Gordon
ENVIRONMENTAL MICROBIOLOGY
(2018)
Article
Multidisciplinary Sciences
Gaston De Serres, Danuta M. Skowronski, Brian J. Ward, Michael Gardam, Camille Lemieux, Annalee Yassi, David M. Patrick, Mel Krajden, Mark Loeb, Peter Collignon, Fabrice Carrat
Article
Microbiology
David M. Gordon, Sarah Geyik, Olivier Clermont, Claire L. O'Brien, Shiwei Huang, Charmalie Abayasekara, Ashwin Rajesh, Karina Kennedy, Peter Collignon, Paul Pavli, Christophe Rodriguez, Brian D. Johnston, James R. Johnson, Jean-Winoc Decousser, Erick Denamur
Article
Public, Environmental & Occupational Health
Awa Aidara-Kane, Frederick J. Angulo, John M. Conly, Yuki Minato, Ellen K. Silbergeld, Scott A. McEwen, Peter J. Collignon
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2018)
Article
Multidisciplinary Sciences
Oyebola Fasugba, Brett G. Mitchell, George Mnatzaganian, Anindita Das, Peter Collignon, Anne Gardner
Article
Medicine, General & Internal
Peter Collignon
Summary: COVID-19, caused by the coronavirus SARS-CoV-2, spreads readily through respiratory route and droplets. Interventions like isolation and social distancing are crucial in reducing transmission, until widespread vaccination can provide a lasting solution. Lockdowns and restrictions have unintended consequences, therefore, measures should be proportionate to the risk and vary based on local conditions.
INTERNAL MEDICINE JOURNAL
(2021)
Article
Infectious Diseases
Peter Collignon, John J. Beggs
JAC-ANTIMICROBIAL RESISTANCE
(2020)
Review
Infectious Diseases
Peter J. Collignon, Scott A. McEwen
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2019)
Article
Public, Environmental & Occupational Health
Ramon Z. Shaban, Samuel Maloney, John Gerrard, Peter Collignon, Deborough Macbeth, Marilyn Cruickshank, Anna Hume, Amy V. Jennison, Rikki M. A. Graham, Haakon Bergh, Heather L. Wilson, Petra Derrington
AMERICAN JOURNAL OF INFECTION CONTROL
(2017)
Letter
Immunology
Peter J. Collignon, John M. Conly, Antoine Andremont, Scott A. McEwen, Awa Aidara-Kane
CLINICAL INFECTIOUS DISEASES
(2017)
Article
Infectious Diseases
Geoffrey W. Coombs, Denise A. Daley, Yung Thin Lee, Julie C. Pearson, J. Owen Robinson, Graeme R. Nimmo, Peter Collignon, Benjamin P. Howden, Jan M. Bell, John D. Turnidge
COMMUNICABLE DISEASES INTELLIGENCE
(2016)
Article
Public, Environmental & Occupational Health
Anindita Das, Karina Kennedy, Gloria Spyropoulos, Peter Collignon
INFECTION DISEASE & HEALTH
(2016)
Article
Public, Environmental & Occupational Health
Allen C. Cheng, Andrew J. Stewardson, Brett G. Mitchell, Peter Collignon, Paul D. Johnson, Rhonda L. Stuart
INFECTION DISEASE & HEALTH
(2016)
