Review
Plant Sciences
Lu Liu, Jun Liu, Ning Xu
Summary: Lectin receptor-like kinases (LecRKs) are located on the cell membrane and play diverse roles in environmental perception in higher plants. They are involved in plant development and response to abiotic and biotic stresses. This review summarizes the identified ligands of LecRKs in Arabidopsis, as well as discussing the posttranslational modification of these receptors in plant innate immunity and future research perspectives on plant LecRKs.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Martin Stegmann, Patricia Zecua-Ramirez, Christina Ludwig, Ho-Seok Lee, Brenda Peterson, Zachary L. Nimchuk, Youssef Belkhadir, Ralph Hueckelhoven
Summary: Plant immune responses need to be tightly controlled for proper allocation of resources for growth and development. Recent research has discovered that some endogenous signaling peptides not only regulate plant development and growth but also play a regulatory role in plant immune responses. In this study, GLV2 peptides are identified as phytocytokines in Arabidopsis thaliana, enhancing sensitivity to bacterial elicitors and contributing to resistance against bacterial pathogens. The GLV2 signaling is perceived by RGI receptors and promotes PRR abundance independent of transcriptional regulation, controlling plant immunity through a previously undescribed phytocytokine activity mechanism.
Article
Plant Sciences
Zhen Gong, Guan-Zhu Han
Summary: Phylogenomic analyses of RLKs across plants revealed their presence in streptophytes, some chlorophytes, one prasinodermophyte, and one glaucophyte, but not in rhodophytes. The copy number of RLKs in streptophytes increased drastically after a certain point in evolution. Charophyte RLKs are diverse and seed the major diversity of land plant RLKs, suggesting modular evolution through domain gains or losses. Positive selection in charophyte RLK groups indicates potential functions in host-microbe interaction.
Article
Biochemistry & Molecular Biology
Xiao Yu, Yingpeng Xie, Dexian Luo, Hai Liu, Marcos V. V. de Oliveira, Peipei Qi, Sung-Il Kim, Fausto Andres Ortiz-Morea, Jun Liu, Yafei Chen, Sixue Chen, Barbara Rodrigues, Bo Li, Shaowu Xue, Ping He, Libo Shan
Summary: Enabling and constraining immune activation is crucial for maintaining cellular homeostasis. In Arabidopsis, BTL2, an uncharacterized receptor kinase, senses the integrity of BAK1/SERK4 and promotes NLR-mediated phytocytokine signaling, leading to autoimmunity. BTL2 forms complexes with multiple phytocytokine receptors, connecting PRR and NLR-mediated immunity.
Review
Plant Sciences
Gara Romero-Hernandez, Manuel Martinez
Summary: The success of plant response to environmental stressors depends on regulatory networks and phosphorylation plays a key role in activating or deactivating proteins. Protein kinases are responsible for phosphorylation and play an important role in signal transmission. This review focuses on the contribution of protein kinases to herbivore-triggered responses in plants.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Akanksha Gandhi, Ralf Oelmueller
Summary: Plants rely on membrane-bound receptor-like kinases (RLKs) to perceive and respond to stress signals. While they play a crucial role in growth, reproduction, hormone perception, and defense responses against biotic stresses, their involvement in abiotic stress responses is not well-documented. This review summarizes the sub-classes of RLKs based on their domain structure and discusses their specific role in abiotic stress adaptation. The importance of RLKs in abiotic stress responses and their potential for engineering stress-tolerant crop varieties are highlighted.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Zunyong Liu, Shuguo Hou, Olivier Rodrigues, Ping Wang, Dexian Luo, Shintaro Munemasa, Jiaxin Lei, Jun Liu, Fausto Andres Ortiz-Morea, Xin Wang, Kinya Nomura, Chuanchun Yin, Hongbo Wang, Wei Zhang, Keyan Zhu-Salzman, Sheng Yang He, Ping He, Libo Shan
Summary: Stomatal reopening in plants is dynamically regulated by the interaction between secreted peptides SCREWs and the receptor kinase NUT. This system counter-regulates the closure of stomata induced by abscisic acid and microbe-associated molecular patterns. SCREWs trigger the phosphorylation of key proteins involved in stomatal closure, leading to increased activity of kinase OST1 and reduced activity of anion channels. The SCREW-NUT system plays an important role in preventing uncontrolled stomatal closure and optimizing plant fitness.
Review
Biochemistry & Molecular Biology
Liangliang Chen, Keiko U. Torii
Summary: The proper development and function of stomata, which are valves for gas-exchange and water control, are crucial for plant survival and productivity. It has been discovered that various receptor kinases regulate both stomatal development and immunity. Despite occurring at different cellular time scales, these two signaling pathways share similar components and regulatory modules. This review presents an overview of the current knowledge on the components of stomatal development and immunity signaling, and offers a synthesis and perspectives on understanding the conservation and specificity of these pathways.
Article
Plant Sciences
Tongjun Sun, Yuelin Zhang
Summary: Plant cells can recognize and respond to microbial pathogens by producing defense signaling molecules, which can spread locally and activate immune responses. Local damage can also release immunogenic signals, further enhancing immune responses in surrounding cells. Activation of local defense responses leads to the production of long-distance defense signals, which can activate systemic acquired resistance.
Article
Multidisciplinary Sciences
Aolin Jia, Shijia Huang, Wen Song, Junli Wang, Yonggang Meng, Yue Sun, Lina Xu, Henriette Laessle, Jan Jirschitzka, Jiao Hou, Tiantian Zhang, Wenquan Yu, Giuliana Hessler, Ertong Li, Shoucai Ma, Dongli Yu, Jan Gebauer, Ulrich Baumann, Xiaohui Liu, Zhifu Han, Junbiao Chang, Jane E. Parker, Jijie Chai
Summary: In this study, the researchers discovered the enzymatic activity of TIR proteins, which can catalyze the ribosylation of ADP to ATP and ADPR. This enzymatic activity plays a role in activating the immune branch in plants.
Editorial Material
Plant Sciences
Ralf Muller-Xing, Qian Xing
Summary: The study reveals that MAZZA is a novel intracellular interactor of the CLV1f receptors, shedding light on how CLV1f signals are transmitted intracellularly.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Review
Plant Sciences
Qingfeng Zhu, Yanzhao Feng, Jiao Xue, Pei Chen, Aixia Zhang, Yang Yu
Summary: As plants grow and develop, they face changing environments which trigger stress responses. The large protein family known as receptor-like protein kinases (RLKs) play a role in regulating plant growth, development, and response to stresses. Understanding RLKs' function and mechanisms is important for crop breeding. This review focuses on the recent findings that RLKs simultaneously regulate plant growth and stress adaptation, offering insight into crop improvement.
Article
Biochemistry & Molecular Biology
Ping Li, Lulu Zhao, Fan Qi, Nang Myint Phyu Sin Htwe, Qiuying Li, Dawei Zhang, Fucheng Lin, Keke Shang-Guan, Yan Liang
Summary: The study revealed that RIPK plays a crucial role in regulating ROS production in various layers of the plant immune system, contributing to immune responses. RIPK mutants showed reduced ROS production in response to immune elicitors and increased susceptibility to necrotrophic bacteria.
Review
Plant Sciences
Alice K. Zelman, Gerald Alan Berkowitz
Summary: Endogenous signaling compounds are important for plants to respond to harmful and beneficial organisms. The plant elicitor peptides (Peps) and the endogenous signaling polypeptide systemin play roles in defense responses against pathogens and herbivorous insects. This paper explores the similarities between Peps and systemin in tomato, and discusses the receptors involved. Future research directions for Pep signaling in solanaceous crops are suggested.
Article
Microbiology
Yezhou Hu, Yanxia Ding, Boying Cai, Xiaohui Qin, Jingni Wu, Minhang Yuan, Shiwei Wan, Yang Zhao, Xiu-Fang Xin
Summary: This study reveals that phytopathogen Pseudomonas syringae induces water soaking in plant leaf tissue by altering the regulation of abscisic acid (ABA), which leads to ABA signaling and stomatal closure. P. syringae achieves this by binding and inhibiting Arabidopsis type one protein phosphatases (TOPPs) that normally suppress ABA signaling. This hijacking of ABA signaling and stomatal closure are key mechanisms of disease susceptibility.
CELL HOST & MICROBE
(2022)
Article
Genetics & Heredity
Eleazar Rodriguez, Jonathan Chevalier, Hassan El Ghoul, Kristoffer Voldum-Clausen, John Mundy, Morten Petersen
Article
Multidisciplinary Sciences
Yan Xu, Sibo Wang, Linzhou Li, Sunil Kumar Sahu, Morten Petersen, Xin Liu, Michael Melkonian, Gengyun Zhang, Huan Liu
SCIENTIFIC REPORTS
(2019)
Article
Biochemistry & Molecular Biology
Eleazar Rodriguez, Jonathan Chevalier, Jakob Olsen, Jeppe Ansbol, Vaitsa Kapousidou, Zhangli Zuo, Steingrim Svenning, Christian Loefke, Stefanie Koemeda, Pedro Serrano Drozdowskyj, Jakub Jez, Gerhard Durnberger, Fabian Kuenzl, Michael Schutzbier, Karl Mechtler, Elise Nagel Ebstrup, Signe Lolle, Yasin Dagdas, Morten Petersen
Article
Microbiology
Yan Xu, Linzhou Li, Hongping Liang, Barbara Melkonian, Maike Lorenz, Thomas Friedl, Morten Petersen, Huan Liu, Michael Melkonian, Sibo Wang
Article
Microbiology
Sibo Wang, Linzhou Li, Yan Xu, Barbara Melkonian, Maike Lorenz, Thomas Friedl, Morten Petersen, Sunil Kumar Sahu, Michael Melkonian, Huan Liu
Correction
Ecology
Linzhou Li, Sibo Wang, Hongli Wang, Sunil Kumar Sahu, Birger Marin, Haoyuan Li, Yan Xu, Hongping Liang, Zhen Li, Shifeng Cheng, Tanja Reder, Zehra Cebi, Sebastian Wittek, Morten Petersen, Barbara Melkonian, Hongli Du, Huanming Yang, Jian Wang, Gane Ka-Shu Wong, Xun Xu, Xin Liu, Yves Van de Peer, Michael Melkonian, Huan Liu
NATURE ECOLOGY & EVOLUTION
(2020)
Article
Biochemistry & Molecular Biology
Zhangli Zuo, Milena Roux, Eleazar Rodriguez, Morten Petersen
Summary: The mRNA decapping components LSM1, PAT1, PATH1, and PATH2 are essential for the infection of turnip mosaic virus (TuMV), and TuMV hijacks decapping components via PAT proteins to support viral infection.
MOLECULAR PLANT-MICROBE INTERACTIONS
(2022)
Article
Biology
Zhangli Zuo, Milena E. Roux, Jonathan R. Chevalier, Yasin F. Dagdas, Takafumi Yamashino, Emilie Knight, Lars Ostergaard, Soren Hojgaard, Eleazar Rodriguez, Morten Petersen
Summary: Multicellular organisms perceive and transduce multiple cues to optimize development. Key transcription factors and RNA processing both contribute to tissue development. In this study, it is discovered that the mRNA decay machinery directly targets ASL9 transcripts for decay, possibly interfering with cytokinin/auxin responses during development. These findings shed light on the importance of RNA processing in development.
LIFE SCIENCE ALLIANCE
(2023)
Article
Plant Sciences
Matthias Freh, Jinlan Gao, Morten Petersen, Ralph Panstruga
Summary: The plant immune system relies on immune sensors to defend against phytopathogens. Fine-tuning and proper regulation of the immune system are essential to prevent plant autoimmunity. Recent findings have provided insights into the mechanisms of plant autoimmunity and highlight the importance of NLR expression regulation.
Article
Biochemistry & Molecular Biology
Zhangli Zuo, Milena Edna Roux, Holger Pall Saemundsson, Maren Mueller, Sergi Munne Bosch, Morten Petersen
Summary: The pat1 mutants exhibit hypersensitivity to ABA and transcripts of ABA-responsive genes persist longer in these mutants. They also show increased resistance to drought stress and Pythium irregulare. Experiments demonstrate that PAT1 functions specifically in decapping of the canonical ABA-responsive gene COR15A, mediating decay of ABA-responsive genes and regulating stress responses.
Article
Plant Sciences
Sibo Wang, Linzhou Li, Haoyuan Li, Sunil Kumar Sahu, Hongli Wang, Yan Xu, Wenfei Xian, Bo Song, Hongping Liang, Shifeng Cheng, Yue Chang, Yue Song, Zehra Cebi, Sebastian Wittek, Tanja Reder, Morten Peterson, Huanming Yang, Jian Wang, Barbara Melkonian, Yves van de Peer, Xun Xu, Gane Ka-Shu Wong, Michael Melkonian, Huan Liu, Xin Liu
Article
Cell Biology
Victoria Sanchez-Vera, Chandra Shekar Kenchappa, Katarina Landberg, Simon Bressendorff, Stefan Schwarzbach, Tom Martin, John Mundy, Morten Petersen, Mattias Thelander, Eva Sundberg
Article
Microbiology
Signe Lolle, Christiaan Greeff, Klaus Petersen, Milena Roux, Michael Krogh Jensen, Simon Bressendorff, Eleazar Rodriguez, Kenneth Somark, John Mundy, Morten Petersen
CELL HOST & MICROBE
(2017)