Role of Zika Virus prM Protein in Viral Pathogenicity and Use in Vaccine Development

Zika virus structural biology and progress in vaccine development

(2018) Hsiao-Han Lin et al.   BIOTECHNOLOGY ADVANCES

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials

(2018) Kayvon Modjarrad et al.   LANCET

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

(2018) Martin R Gaudinski et al.   LANCET

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

The Zika virus envelope protein glycan loop regulates virion antigenicity

(2018) Leslie Goo et al.   VIROLOGY

The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

(2018) Sandra Bos et al.   VIROLOGY

Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

(2018) Xiao-Feng Li et al.   Nature Communications

Comparative analysis of protein evolution in the genome of pre-epidemic and epidemic Zika virus

(2017) Arunachalam Ramaiah et al.   INFECTION GENETICS AND EVOLUTION

New insights into flavivirus biology: the influence of pH over interactions between prM and E proteins

(2017) Edson R. A. Oliveira et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Zika Virus Mosquito Vectors: Competence, Biology, and Vector Control

(2017) Elizabeth B Kauffman et al.   JOURNAL OF INFECTIOUS DISEASES

Zika virus: History, epidemiology, transmission, and clinical presentation

(2017) Byung-Hak Song et al.   JOURNAL OF NEUROIMMUNOLOGY

Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans

(2017) Alba Grifoni et al.   JOURNAL OF VIROLOGY

Development of Virus-Like-Particle Vaccine and Reporter Assay for Zika Virus

(2017) Himanshu Garg et al.   JOURNAL OF VIROLOGY

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

(2017) Norbert Pardi et al.   NATURE

The missing pieces: Lack of Zika data from Africa complicates search for answers

(2017) Nicole Wetsman   NATURE MEDICINE

Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine — Preliminary Report

(2017) Pablo Tebas et al.   NEW ENGLAND JOURNAL OF MEDICINE

A single mutation in the prM protein of Zika virus contributes to fetal microcephaly

(2017) Ling Yuan et al.   SCIENCE

Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis

(2017) Xuping Xie et al.   mBio

Zika Virus Infection as a Cause of Congenital Brain Abnormalities and Guillain–Barré Syndrome: Systematic Review

(2017) Fabienne Krauer et al.   PLOS MEDICINE

A DNA Vaccine Protects Human Immune Cells against Zika Virus Infection in Humanized Mice

(2017) Guohua Yi et al.   EBioMedicine

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

(2017) Yaoxing Wu et al.   Cell Discovery

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

(2017) Jasdave S. Chahal et al.   Scientific Reports

From Mosquitos to Humans: Genetic Evolution of Zika Virus

(2016) Lulan Wang et al.   Cell Host & Microbe

Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody

(2016) Lianpan Dai et al.   Cell Host & Microbe

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Aedes albopictus(Diptera: Culicidae) and Mosquito-Borne Viruses in the United States: Table 1.

(2016) Dana L. Vanlandingham et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Zika virus – an overview

(2016) Camila Zanluca et al.   MICROBES AND INFECTION

Structure of the thermally stable Zika virus

(2016) Victor A. Kostyuchenko et al.   NATURE

Vaccine protection against Zika virus from Brazil

(2016) Rafael A. Larocca et al.   NATURE

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic

(2016) Zheng Zhu et al.   Emerging Microbes & Infections

Zika Virus Spreads to New Areas — Region of the Americas, May 2015–January 2016

(2016) Morgan Hennessey et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Detection of Zika Virus Infection in Thailand, 2012–2014

(2015) Rome Buathong et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Detection of Zika virus in saliva

(2015) Didier Musso et al.   JOURNAL OF CLINICAL VIROLOGY

Zika virus infection complicated by Guillain-Barré syndrome – case report, French Polynesia, December 2013

(2014) E Oehler et al.   Eurosurveillance

Molecular Evolution of Zika Virus during Its Emergence in the 20th Century

(2014) Oumar Faye et al.   PLoS Neglected Tropical Diseases

Zika Virus Infection Acquired During Brief Travel to Indonesia

(2013) Jason C. Kwong et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Degrees of maturity: the complex structure and biology of flaviviruses

(2012) Theodore C Pierson et al.   Current Opinion in Virology

A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles

(2011) K. Yoshii et al.   JOURNAL OF GENERAL VIROLOGY

Expression of HLA Class II Molecules in Humanized NOD.Rag1KO.IL2RgcKO Mice Is Critical for Development and Function of Human T and B Cells

(2011) Rebecca Danner et al.   PLoS One

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation

(2008) L. Li et al.   SCIENCE