Article
Infectious Diseases
Gladys Prado, Elisa Teixeira Mendes, Roberta Cristina Ruedas Martins, Lauro Vieira Perdigao-Neto, Maristela Pinheiro Freire, Ana Paula Marchi, Marina Farrel Cortes, Victor Augusto Camarinha de Castro Lima, Flavia Rossi, Thais Guimaraes, Anna Sara Levin, Silvia Figueiredo Costa
Summary: This study retrospectively examined patients infected with carbapenem-resistant S. marcescens and found that the combination of bla KPC-2 with ompC or ompF mutation was the main mechanism of resistance. Additionally, previous use of polymyxin was identified as an independent risk factor for infection with this pathogen.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2022)
Article
Microbiology
Elias Dahdouh, Fernando Lazaro-Perona, Guillermo Ruiz-Carrascoso, Laura Sanchez Garcia, Miguel Saenz de Pipaon, Jesus Mingorance
Summary: The study found that intestinal dominance by Serratia spp. in neonates plays a significant role in outbreaks and extraintestinal spread.
Article
Public, Environmental & Occupational Health
A. Gery, A. Mouet, F. Gravey, M. Fines-Guyon, F. Guerin, F. Ethuin, F. Borgey, J. Lubrano, S. Le Hello
Summary: Early postoperative infections caused by Serratia marcescens have been reported in our teaching hospital, leading to an investigation into a outbreak linked to a contaminated intraoperative probe. This investigation involved clinical, epidemiological, environmental, and genomic factors to determine the source of infection.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Public, Environmental & Occupational Health
X. Liu, Z. Yan, L. Ye, K. Wang, J. Li, Y. Lin, C. Liao, Y. Liu, P. Li, M. Du
Summary: This study traced an outbreak of Serratia marcescens infection in neurosurgical patients to contaminated haircutting tools in the hospital barber shop. The outbreak ended after reinforcing infection control procedures and re-educating the barbers.
JOURNAL OF HOSPITAL INFECTION
(2023)
Article
Microbiology
Stefanie Kampmeier, Karola Prior, Scott A. Cunningham, Abhinav Goyal, Dag Harmsen, Robin Patel, Alexander Mellmann
Summary: A novel cgMLST scheme for S. marcescens was developed and evaluated in this study, showing promising results in typing efforts for molecular surveillance and outbreak investigation. The scheme aims to improve standardization and facilitate interlaboratory comparisons, ultimately enhancing understanding of S. marcescens genomic epidemiology.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Article
Environmental Sciences
Jing Luo, Yanxia Cheng, Libin Guo, Aoli Wang, Min Lu, Letian Xu
Summary: Diet plays a crucial role in shaping insects' phenotype and gut microbiota, with imbalanced diets leading to significantly higher mortality in host insects and altering the abundance and composition of gut microbiome. The study suggests that diet-induced variation in gut microbiota may have detrimental effects on host insects, advancing our understanding of omnivorous insects' forage allocation strategies.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Microbiology
Angel Rodriguez-Villodres, Jose Manuel Ortiz de la Rosa, Raquel Valencia-Martin, Francisco Jimenez Parrilla, Guillermo Martin-Gutierrez, Natividad Marquez Patino, Estela Perea Cruz, Maria Teresa Sanchez Jimenez, Antonio Pavon Delgado, Jose Miguel Cisneros, Jose Antonio Lepe
Summary: The study evaluated the clinical and epidemiological impact of a qPCR-based molecular surveillance strategy on controlling the outbreak of S. marcescens in a Neonatal Intensive Care Unit (NICU). The results showed that the implementation of the qPCR strategy effectively controlled the spread of infection and significantly reduced the occurrence of bloodstream infections. The study demonstrated that qPCR can be a useful tool for the prevention and control of healthcare-associated infections.
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
(2023)
Article
Food Science & Technology
Pisut Keawmanee, Chainarong Rattanakreetakul, Ratiya Pongpisutta
Summary: Fumonisin (FB) contamination in maize products in Southeast Asia poses a major health concern for humans and animals. A study identified Serratia marcescens as a promising bacterium for reducing fumonisin levels, and further research on the production of FB1-reducing enzymes is recommended.
Review
Infectious Diseases
Radica Zivkovic Zaric, Milan Zaric, Marija Sekulic, Nenad Zornic, Jelena Nesic, Vesna Rosic, Tatjana Vulovic, Marko Spasic, Marko Vuleta, Jovan Jovanovic, Dalibor Jovanovic, Stefan Jakovljevic, Petar Canovic
Summary: This study conducted a systematic review to determine the invasive infections caused by Serratia marcescens (SM) and established the most appropriate antibiotic therapy. The study found that SM is resistant to a wide range of antibiotics. Treatment of SM infections should include the combination of carbapenems or aminoglycosides with third-generation (and possibly fourth-generation) cephalosporin.
Article
Green & Sustainable Science & Technology
Dafne Lecca-Caballero, Eyber Vega-Moreno, Luis Cabanillas-Chirinos, Karen Diaz Del Aguila, Walter Rojas-Villacorta, Waldo Salvatierra-Espinola, Renny Nazario Naveda, Segundo Rojas-Flores, Magaly de la Cruz-noriega
Summary: Heavy metal contamination of water is a significant problem in Peru, posing a potential threat to the ecosystem. Bacteria, such as Serratia marcescens, offer an ecological alternative for treating these effluents. This research investigates the influence of temperature and pH on lead bioremoval in surface water and identifies optimal treatment conditions.
Article
Microbiology
Megan E. Hardy, Rachel M. Kenney, Robert J. Tibbetts, Anita B. Shallal, Michael P. Veve
Summary: This study evaluated the impact of an AmpC stewardship intervention on the definitive treatment of low- and no-risk Enterobacterales, and found that the antimicrobial stewardship intervention was associated with increased ceftriaxone prescribing and similar patient outcomes.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2023)
Article
Public, Environmental & Occupational Health
A. Muyldermans, F. Crombe, P. Bosmans, F. Cools, D. Pierard, I Wybo
Summary: Analysis of a Serratia marcescens outbreak in an NICU from 2018-2019 revealed that replacing siphons and weekly decontamination with acetic acid were key infection control measures. Whole-genome sequencing (WGS) enabled faster recognition and accurate mapping of the outbreak, facilitating the implementation of control measures. Additionally, WGS provided valuable insights into the spread of antibiotic resistance and virulence genes.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Multidisciplinary Sciences
Yosuke Asano, Yoshinori Matsumoto, Jose La Rose, Fang He, Takayuki Katsuyama, Wang Ziyi, Shigetomo Tsuji, Hiroshi Kamioka, Robert Rottapel, Jun Wada
Summary: By adding Benzonase to reduce cell clumping and viscosity caused by collagenase digestion of calvariae, the study increased the number of collected primary murine osteoblasts. This new isolation protocol minimizes the use of neonatal pups for in vitro studies and suggests that Benzonase could be used to modify the isolation of other difficult-to-purify cell populations.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
Lukas Bechmann, Ralf Boettger, Claas Baier, Aljoscha Tersteegen, Katja Bauer, Achim J. Kaasch, Gernot Geginat
Summary: This retrospective case-control study investigated the origin of a Serratia marcescens outbreak in a neonatal intensive care unit. The study found that the infection originated from a breast milk donor. The outbreak was controlled through the implementation of an infection control bundle and strict hygiene measures.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Immunology
Martin A. Gonzalez-Montalvo, Faviola Tavares-Carreon, Gloria M. Gonzalez, Hiram Villanueva-Lozano, Inmaculada Garcia-Romero, Viviana C. Zomosa-Signoret, Miguel A. Valvano, Angel Andrade
Summary: Chaperone-usher (CU) fimbriae are prevalent among Enterobacteriaceae and play key roles in biofilm formation and host cell interactions. This study identified 421 FUPs in 39 S. marcescens genomes, classified them into 20 CU operons, and proposed new nomenclature based on FUP sequence phylogeny. In vivo transcriptional assays showed that promoters from 3 core CU operons are predominantly expressed in environmental and clinical S. marcescens isolates, indicating their potential role in pathogenesis.
MICROBIAL PATHOGENESIS
(2021)