Article
Agriculture, Dairy & Animal Science
Kyung-Hyo Do, Kwangwon Seo, Myunghwan Jung, Woo-Kon Lee, Wan-Kyu Lee
Summary: The study compared virulence factors and antibiotic resistance among the most common pathogenic Escherichia coli strains in swine and patients with diarrhea in Korea. The prevalence of enterotoxigenic E. coli (ETEC) was highest in swine (47.1%), followed by Shiga toxin-producing E. coli (STEC) (32.9%). Similarly, the majority of patient isolates were STEC (50.8%), followed by ETEC (23.0%). Swine isolates showed significantly higher resistance to fluoroquinolones compared to patient isolates. Several sequence types (ST) were detected in both swine and humans, indicating susceptibility to cross infection. The study highlights the potential transfer of antimicrobial resistance between swine and humans.
Article
Infectious Diseases
Mohamed Sabry Abd Elraheam Elsayed, Samah Mahmoud Eldsouky, Tamer Roshdy, Lamia Said, Nahed Thabet, Tamer Allam, A. B. Abeer Mohammed, Ghada M. Nasr, Mohamed S. M. Basiouny, Behairy A. Akl, Maha M. Nader, Al Shaimaa Hasan, Ahmed Salah
Summary: Pasteurella multocida isolates recovered from apparently healthy and diseased cattle and humans in Egypt showed diverse capsular types and virulence gene combinations, exhibiting high levels of antimicrobial resistance. Detection of resistance genes co-occurrence led to multiple drug-resistant phenotypes, highlighting the potential risk to livestock and humans.
Article
Infectious Diseases
Miguel L. Grilo, Sara Isidoro, Lelia Chambel, Carolina S. Marques, Tiago A. Marques, Carla Sousa-Santos, Joana Robalo, Manuela Oliveira
Summary: The study investigated the interaction between pathogenic agents and critically endangered Iberochondrostoma lusitanicum, revealing increased disease prevalence and pathogenic potential during the dry season. Clinically relevant antimicrobial resistance phenotypes were also detected in Aeromonas isolates from this species. The quality of habitat was identified as a crucial factor for the sustainable development of this fish species, with potential implications for public health due to the individuals acting as reservoirs of important antimicrobial resistant bacteria.
Article
Microbiology
Kyung-Hyo Do, Kwangwon Seo, Wan-Kyu Lee
Summary: This study compared antimicrobial resistance, O-serogroups, virulence genes, and multi-locus sequence type of Escherichia (E.) coli between isolates from pigs and patients suffering from diarrhea, as well as the most prevalent pathogenic E. coli strain from swine isolates in Korea. The results showed that isolates from pigs exhibited significantly higher resistance to fluoroquinolone compared to isolates from patients. Stx2 gene was found in both pig and human isolates, which could potentially cause severe disease. The study also suggested that pigs could act as a reservoir for human infection and transfer antimicrobial resistance to humans.
Article
Infectious Diseases
Minhian Chai, Muhammad Zikree Sukiman, Amirah Huda Kamarun Baharin, Insyirah Ramlan, Lennard Zhunhoong Lai, Yeewen Liew, Pavitra Malayandy, Noor Muzamil Mohamad, Siewshean Choong, Siti Mariam Zainal Ariffin, Mohd Faizal Ghazali
Summary: This study investigated the prevalence and antibiotic susceptibility profile of S. aureus in animal handlers in Peninsular Malaysia. The study found a high carriage rate of S. aureus, including MRSA and MDRSA, in animal handlers, with resistance to several common antibiotics. The study also revealed that animal handlers with close exposure to poultry were more likely to carry S. aureus strains resistant to certain antibiotics.
Article
Microbiology
Shuyang Yu, Yuxuan Zhou, Dan Feng, Quangui Jiang, Tianle Li, Guilai Jiang, Zhemin Zhou, Heng Li
Summary: This study investigated the genetic characteristics, antimicrobial resistance, and virulent factors of multidrug-resistant Staphylococcus aureus isolated from 22 food poisoning incidents in Eastern China from 2011 to 2021. The results indicated that methicillin-resistant Staphylococcus aureus (MRSA), particularly CC398, was the predominant strain involved in these incidents. The study also revealed diverse contamination patterns and a low prevalence of multidrug resistance among the isolates.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Zunita Zakaria, Latiffah Hassan, Zawiyah Sharif, Norazah Ahmad, Rohaya Mohd Ali, Suraya Amir Husin, Norfitriah Mohamed Sohaimi, Shafini Abu Bakar, Bashiru Garba
Summary: This study investigated the pathogenicity, antimicrobial resistance, and multilocus sequence types of Salmonella enterica subspecies enterica serovar Enteritidis in the central region of peninsular Malaysia. The isolates showed multidrug-resistance features and had various virulence genes. The findings suggest potential risks to humans and livestock from this foodborne pathogen.
Article
Agriculture, Dairy & Animal Science
Faten Ben Chehida, Haythem Gharsa, Wafa Tombari, Rachid Selmi, Sana Khaldi, Monia Daaloul, Karim Ben Slama, Lilia Messadi
Summary: The one-humped camel (Camelus dromedarius) plays a significant role in livestock economy, especially in Africa where they are used for meat production, live animal export, and milk production. However, these camels are susceptible to various pathogens, including Staphylococcus aureus, which can cause economic losses. Monitoring and controlling the spread of this bacterium is crucial as it is an important zoonotic disease.
Article
Infectious Diseases
Mitra Ahmadi, Reza Ranjbar, Payam Behzadi, Taher Mohammadian
Summary: This study identified and characterized clinical strains of Klebsiella pneumoniae, revealing a high prevalence of antibiotic resistance and virulence genes. The study highlights the significant pathogenic potential of isolated pathotypes of K. pneumoniae.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
(2022)
Article
Veterinary Sciences
Ting Gan, Gang Shu, Hualin Fu, Qigui Yan, Wei Zhang, Huaqiao Tang, Lizi Yin, Ling Zhao, Juchun Lin
Summary: S. aureus isolates from food animals in Sichuan province of China demonstrate severe antimicrobial resistance with various resistance genes, especially MRSA isolates. The genetic pool of MRSA isolates is diverse and complex, indicating the need for further investigation.
BMC VETERINARY RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Gang Chen, Yue Hou, Liyan Ye, Qiang Zhao, Jie Liu, Zhaoyan Wang
Summary: In this study, we found no significant correlation between virulence genes from S. lugdunensis isolates and the site of infection. The fbl-typing method can better distinguish different pathogenic phenotypes and has the advantages of convenience, low cost, and high repeatability.
FRONTIERS IN BIOSCIENCE-LANDMARK
(2023)
Article
Infectious Diseases
Maximo Petrocchi-Rilo, Sonia Martinez-Martinez, Alvaro Aguaron-Turrientes, Elisabet Roca-Martinez, Maria-Jose Garcia-Iglesias, Esther Perez-Fernandez, Alba Gonzalez-Fernandez, Elena Herencia-Lagunar, Cesar-Bernardo Gutierrez-Martin
Summary: A diverse set of Streptococcus suis isolates from Spain in 2019 to 2020 showed various serotypes and pathotypes, with serotypes 2 and 9 mainly associated with CNS infections, serotype 1 with joint infections, and serotype 3 with lung infections. The S. suis isolates exhibited high global antimicrobial resistance, with ampicillin, spectinomycin, and tiamulin showing the highest activities.
Article
Agriculture, Dairy & Animal Science
Jiakang Li, Lei Yang, Xuelin Huang, Yiping Wen, Qin Zhao, Xiaobo Huang, Jing Xia, Yong Huang, Sanjie Cao, Senyan Du, Rui Wu, Likou Zou, Qigui Yan, Xinfeng Han
Summary: This study revealed a high prevalence of multidrug-resistant Enterococcus faecalis in ducks, with the potential for transmission to humans due to the presence of various resistance and virulence genes. The findings highlight the importance of monitoring antimicrobial resistance in poultry to prevent the spread of potentially harmful pathogens.
Article
Veterinary Sciences
Gui-Lin Wen, Shi-Hong Li, Zhe Qin, Ya-Jun Yang, Li-Xia Bai, Wen-Bo Ge, Xi-Wang Liu, Jian-Yong Li
Summary: This study isolated and characterized Clostridium difficile strains from clinical diseased dogs and cats, and found that the bacteria were quietly prevalent in pets with varying toxicities and genotypes. The isolates were highly susceptible to vancomycin and metronidazole but resistant to erythromycin and ciprofloxacin. The study highlights the importance of studying and paying attention to CDI in pets.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Microbiology
Zhuru Hou, Benjin Xu, Ling Liu, Rongrong Yan, Jinjing Zhang, Jiaxin Yin, Peipei Li, Jianhong Wei
Summary: This study investigated the prevalence and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains in a tertiary hospital in Shanxi Province, China. The majority of MRSA strains showed high resistance to commonly used antibiotics and carried multiple resistance genes and virulence genes. The most common MRSA epidemic clone was ST59-SCCmecIV-t437, which exhibited high resistance and strong pathogenicity. These findings are important for understanding the drug resistance and pathogenesis of MRSA.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemical Research Methods
Sharda Prasad Awasthi, Nityananda Chowdhury, Sucharit Basu Neogi, Atsushi Hinenoya, Noritoshi Hatanaka, Goutam Chowdhury, T. Ramamurthy, Shinji Yamasaki
JOURNAL OF MICROBIOLOGICAL METHODS
(2019)
Article
Microbiology
Sonia Jain, Rukhsana Chowdhury, Mousumi Datta, Goutam Chowdhury, Asish Kumar Mukhopadhyay
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
(2019)
Article
Microbiology
Goutam Chowdhury, Thandavarayan Ramamurthy, Amit Ghosh, Shanta Dutta, Eizo Takahashi, Asish K. Mukhopadhyay
Article
Microbiology
Anirban Sarkar, Daichi Morita, Amit Ghosh, Goutam Chowdhury, Asish K. Mukhopadhyay, Keinosuke Okamoto, Thandavarayan Ramamurthy
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Microbiology
Priyanka Jain, Goutam Chowdhury, Sriparna Samajpati, Surajit Basak, Arindam Ganai, Sandip Samanta, Keinosuke Okamoto, Asish K. Mukhopadhyay, Shanta Dutta
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2020)
Article
Chemistry, Analytical
Pandiyaraj Kanagavalli, Sivaprakasam Radhakrishnan, Gaurav Pandey, Velayutham Ravichandiran, Gururaja Perumal Pazhani, Murugan Veerapandian, Gurumurthy Hegde
Article
Immunology
Daichi Morita, Eizo Takahashi, Masatomo Morita, Makoto Ohnishi, Tamaki Mizuno, Shin-ichi Miyoshi, Devarati Dutta, Thandavarayan Ramamurthy, Goutam Chowdhury, Asish K. Mukhopadhyay, Keinosuke Okamoto
MICROBIOLOGY AND IMMUNOLOGY
(2020)
Article
Pharmacology & Pharmacy
Subha Sankar Paul, Eizo Takahashi, Goutam Chowdhury, Shin-ichi Miyoshi, Tamaki Mizuno, Asish K. Mukhopadhyay, Shanta Dutta, Keinosuke Okamoto
BIOLOGICAL & PHARMACEUTICAL BULLETIN
(2020)
Article
Multidisciplinary Sciences
Thandavarayan Ramamurthy, Agila Kumari Pragasam, Alyce Taylor-Brown, Robert C. Will, Karthick Vasudevan, Bhabatosh Das, Sunil Kumar Srivastava, Goutam Chowdhury, Asish K. Mukhopadhyay, Shanta Dutta, Balaji Veeraraghavan, Nicholas R. Thomson, Naresh C. Sharma, Gopinath Balakrish Nair, Yoshifumi Takeda, Amit Ghosh, Gordon Dougan, Ankur Mutreja
Summary: This study describes the genomic epidemiology of the O139 Vibrio cholerae serogroup and identifies changes in virulence and antimicrobial resistance characteristics that may have contributed to its decline.
NATURE COMMUNICATIONS
(2022)
Article
Infectious Diseases
Goutam Chowdhury, Thandavarayan Ramamurthy, Bhabatosh Das, Debjani Ghosh, Keinosuke Okamoto, Shin-ichi Miyoshi, Shanta Dutta, Asish K. Mukhopadhyay
Summary: In this study, bla(NDM-5)-positive multidrug resistance commensal Escherichia coli (CE) strains were isolated from diarrheal patients in Kolkata, India. The strains showed resistance to multiple antibiotics and carried various antimicrobial resistance genes. The bla(NDM-5) gene was located on a plasmid with the potential to transfer to other enteric pathogens.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Microbiology
Goutam Chowdhury, Bhabatosh Das, Shakti Kumar, Archana Pant, Priyadarshini Mukherjee, Debjani Ghosh, Hemanta Koley, Shin-ichi Miyoshi, Keinosuke Okamoto, Alapan Paul, Shanta Dutta, Thandavarayan Ramamurthy, Asish K. Mukhopadyay
Summary: The aim of this study was to characterize extensively drug-resistant Pseudomonas aeruginosa from a patient with diarrhea. Antimicrobial susceptibility testing revealed that P. aeruginosa had a wide spectrum of resistance to antibiotics. Genomic analysis identified 76 genes associated with antimicrobial resistance, xenobiotic degradation, and the type three secretion system. This is the first report on diarrhea associated with P. aeruginosa, suggesting dysbiosis due to antibiotic exposure and the potential role of T3SS in in vivo toxicity of the pathogen.
FUTURE MICROBIOLOGY
(2023)
Article
Immunology
Soumalya Banerjee, Prolay Halder, Sanjib Das, Suhrid Maiti, Ushasi Bhaumik, Moumita Dutta, Goutam Chowdhury, Kei Kitahara, Shin-ichi Miyoshi, Asish Kumar Mukhopadhyay, Shanta Dutta, Hemanta Koley
Summary: This study suggests that POMVs, formulated with five DEC pathotypes, are immunogenic and provide broad-spectrum passive protection in neonatal mice.
IMMUNOLOGY LETTERS
(2023)
Article
Microbiology
Daichi Morita, Masatomo Morita, Munirul Alam, Asish K. Mukhopadhyay, Fatema-tuz Johura, Marzia Sultana, Shirajum Monira, Niyaz Ahmed, Goutam Chowdhury, Shanta Dutta, Thandavarayan Ramamurthy, Prosenjit Samanta, Eizo Takahashi, Keinosuke Okamoto, Hidemasa Izumiya, Makoto Ohnishi
Article
Infectious Diseases
Naresh Chand Sharma, Dhirendra Kumar, Anirban Sarkar, Goutam Chowdhury, Asish K. Mukhopadhyay, Thandavarayan Ramamurthy
JAPANESE JOURNAL OF INFECTIOUS DISEASES
(2020)
Article
Multidisciplinary Sciences
Sailen Guin, Murugan B. Saravanan, Anjay, Goutam Chowdhury, Gururaja Perumal Pazhani, Thandavarayan Ramamurthy, Suresh Chandra Das
