期刊
EXPERIMENTAL BRAIN RESEARCH
卷 202, 期 3, 页码 591-604出版社
SPRINGER
DOI: 10.1007/s00221-010-2162-1
关键词
Basal ganglia; Cerebrovascular; Walking; Locomotion; Hemiparesis; Steering
资金
- Stroke Association Project
This study quantitatively describes differences between participants with hemiparetic stroke and age-matched healthy participants in axial body segment and gait kinematics during a direction change task. Participants were required to change walking direction by 45A degrees, either to their left or right, at the midpoint of a 6-m path. Participants were visually cued either at the start of the walk (pre-planned) or one stride before they reached the turn point (reactive). The sequence and inter-segmental timing of axial orientation onset was preserved in participants with stroke. Analysis of a subgroup of stroke survivors indicated that participants with lesions affecting the basal ganglia (BG) took significantly longer time than control participants to initiate the reorientation synergy when making turns to their non-paretic side. We hypothesize that these differences are a product of asymmetrical activity of dopaminergic pathways in the brain resulting from compromised BG function.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据