Discovery of a small molecule that inhibits bacterial ribosome biogenesis

Protein-guided RNA dynamics during early ribosome assembly

(2014) Hajin Kim et al.   NATURE

Functional Interaction between Ribosomal Protein L6 and RbgA during Ribosome Assembly

(2014) Megha Gulati et al.   PLoS Genetics

In Vivo X-Ray Footprinting of Pre-30S Ribosomes Reveals Chaperone-Dependent Remodeling of Late Assembly Intermediates

(2013) Sarah F. Clatterbuck Soper et al.   MOLECULAR CELL

Structures of the human and Drosophila 80S ribosome

(2013) Andreas M. Anger et al.   NATURE

Functional domains of the 50S subunit mature late in the assembly process

(2013) A. Jomaa et al.   NUCLEIC ACIDS RESEARCH

Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit

(2013) N. Li et al.   NUCLEIC ACIDS RESEARCH

Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process

(2013) Qiang Guo et al.   NUCLEIC ACIDS RESEARCH

How Should We Think About the Ribosome?

(2012) Peter B. Moore   Annual Review of Biophysics

A Translation-Like Cycle Is a Quality Control Checkpoint for Maturing 40S Ribosome Subunits

(2012) Bethany S. Strunk et al.   CELL

Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

(2012) Daniel Boehringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Ribosome Biogenesis Landscape in E. coli Using Quantitative Mass Spectrometry

(2012) Stephen S. Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Measuring the dynamics of E. coli ribosome biogenesis using pulse-labeling and quantitative mass spectrometry

(2012) Stephen S. Chen et al.   Molecular BioSystems

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

(2012) Simon Lebaron et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Assembly of Bacterial Ribosomes

(2011) Zahra Shajani et al.   Annual Review of Biochemistry

Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins

(2011) Triinu Siibak et al.   MOLECULAR MICROBIOLOGY

Understanding ribosome assembly: the structure of in vivo assembled immature 30S subunits revealed by cryo-electron microscopy

(2011) A. Jomaa et al.   RNA

Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

(2011) B. S. Strunk et al.   SCIENCE

The Effect of Ribosome Assembly Cofactors on In Vitro 30S Subunit Reconstitution

(2010) Anne E. Bunner et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Proteomic Analysis of Ribosome Assembly and Turnover In Vivo

(2010) Michael T. Sykes et al.   JOURNAL OF MOLECULAR BIOLOGY

Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for the 30SSubunit

(2010) Anke M. Mulder et al.   SCIENCE

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Inhibition of Bacterial Ribosome Assembly: a Suitable Drug Target?

(2009) B. A. Maguire   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Quantitative Analysis of Isotope Distributions In Proteomic Mass Spectrometry Using Least-Squares Fourier Transform Convolution

(2008) Edit Sperling et al.   ANALYTICAL CHEMISTRY

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly Defects Are Secondary Effects of Protein Synthesis Inhibition

(2008) T. Siibak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Interaction Screens with Ordered Overexpression and Deletion Clone Sets Implicate the Escherichia coli GTPase YjeQ in Late Ribosome Biogenesis

(2008) T. L. Campbell et al.   JOURNAL OF BACTERIOLOGY

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA

(2008) Keith Connolly et al.   MOLECULAR MICROBIOLOGY