Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells
出版年份 2014 全文链接
标题
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells
作者
关键词
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出版物
eLife
Volume 3, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2014-11-19
DOI
10.7554/elife.04631
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Islet Microenvironment, Modulated by Vascular Endothelial Growth Factor-A Signaling, Promotes β Cell Regeneration
- (2014) Marcela Brissova et al. Cell Metabolism
- The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
- (2014) Junwei Shi et al. MOLECULAR CELL
- M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7
- (2014) Xiangwei Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and -cell protection
- (2014) D. P. Christensen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreas Organogenesis: From Lineage Determination to Morphogenesis
- (2013) Hung Ping Shih et al. Annual Review of Cell and Developmental Biology
- Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis
- (2013) Susan M. Clardy et al. BIOCONJUGATE CHEMISTRY
- Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
- (2013) Bjoern Chapuy et al. CANCER CELL
- Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
- (2013) Jakob Lovén et al. CELL
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure
- (2013) Priti Anand et al. CELL
- How to make a functional -cell
- (2013) F. W. Pagliuca et al. DEVELOPMENT
- Soluble Factors Secreted by T Cells Promote -Cell Proliferation
- (2013) E. Dirice et al. DIABETES
- BET bromodomain inhibition suppresses TH17-mediated pathology
- (2013) Deanna A. Mele et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses
- (2013) A. C. Belkina et al. JOURNAL OF IMMUNOLOGY
- BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes
- (2013) M. C. Patel et al. MOLECULAR AND CELLULAR BIOLOGY
- Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
- (2013) Z Zou et al. ONCOGENE
- Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
- (2013) S. C. J. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proinflammatory and Immunoregulatory Roles of Eicosanoids in T Cells
- (2013) Anna Mari Lone et al. Frontiers in Immunology
- Identification of a novel series of BET family bromodomain inhibitors: Binding mode and profile of I-BET151 (GSK1210151A)
- (2012) Jonathan Seal et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice
- (2012) R. Parsa et al. DIABETES
- Down-regulation of NF-κB Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition
- (2012) Guangtao Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging
- (2012) Wenxian Fu et al. NATURE IMMUNOLOGY
- A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
- (2012) Wenxian Fu et al. NATURE IMMUNOLOGY
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors
- (2012) H. S. Bandukwala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
- (2012) W. W. Lockwood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Place your BETs: the therapeutic potential of bromodomains
- (2012) R.K. Prinjha et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Bromodomains as therapeutic targets
- (2011) Susanne Muller et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- The resolution of inflammation: the devil in the flask and in the details
- (2011) Charles N. Serhan FASEB JOURNAL
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation
- (2011) Rui Zhao et al. NATURE CELL BIOLOGY
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
- (2011) M. A. Kriegel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant
- (2011) Jonathan S. Rink et al. SURGERY
- The changing epidemiology of type 1 diabetes: why is it going through the roof?
- (2010) Kendra Vehik et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells
- (2010) Hsin-Jung Wu et al. IMMUNITY
- TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex
- (2010) S. Dittmer et al. JOURNAL OF CELL SCIENCE
- Adjuvant Immunotherapy Increases Cell Regenerative Factor Reg2 in the Pancreas of Diabetic Mice
- (2010) K. Huszarik et al. JOURNAL OF IMMUNOLOGY
- Donor Pretreatment with DHMEQ Improves Islet Transplantation
- (2010) Tohru Takahashi et al. JOURNAL OF SURGICAL RESEARCH
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Genetics, pathogenesis and clinical interventions in type 1 diabetes
- (2010) Jeffrey A. Bluestone et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Complement: a key system for immune surveillance and homeostasis
- (2010) Daniel Ricklin et al. NATURE IMMUNOLOGY
- Regulation and Function of NF-κB Transcription Factors in the Immune System
- (2009) Sivakumar Vallabhapurapu et al. Annual Review of Immunology
- Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation
- (2009) Diana C. Hargreaves et al. CELL
- A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling
- (2009) Vladimir R. Ramirez-Carrozzi et al. CELL
- A protocol for islet isolation from mouse pancreas
- (2009) Dong-Sheng Li et al. Nature Protocols
- RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes
- (2008) D. E. Nowak et al. MOLECULAR AND CELLULAR BIOLOGY
- Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA
- (2008) B. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
- Integration of metabolism and inflammation by lipid-activated nuclear receptors
- (2008) Steven J. Bensinger et al. NATURE
- PID: the Pathway Interaction Database
- (2008) Carl F. Schaefer et al. NUCLEIC ACIDS RESEARCH
- The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors
- (2008) A. M. D'Alise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Possible Roles of Reg Family Proteins in Pancreatic Islet Cell Growth
- (2008) Jun-Li Liu et al. Endocrine Metabolic & Immune Disorders-Drug Targets
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