Article
Pediatrics
Luisa Cortellazzo Wiel, Giorgio Cozzi, Egidio Barbi
Summary: The research found that opioid-related mortality in adolescents is spreading in the US, with prescription opioids playing a crucial role. Since the late 1990s, the management of pain has led to the overuse of opioids, but this practice has significant limitations.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, General & Internal
Yung-Chi Hsu, Shinn-Long Lin, Chun-Sung Sung, Luo-Ping Ger, Huei-Han Liou, Tso-Chou Lin, Shung-Tai Ho
Summary: Among Taiwanese physicians treating CNCP outpatients registered with the Taiwan FDA in 2011, pain specialists had a better understanding and more positive attitude towards long-term opioid prescriptions compared to nonpain board-certified physicians. The major barriers perceived by all physicians were reluctance to prescribe opioids and inadequate knowledge of pain management. Further education on chronic pain management is necessary for clinical practice improvement.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2021)
Article
Environmental Sciences
Ellen Tromp, Anouk te Nijenhuis, Han Knoeff
Summary: The Dutch regional water authorities have the daunting task of strengthening dikes and civil engineering structures. The Dutch Flood Protection Programme (DFPP) is funding and supporting this operation. Innovation is seen as the way forward to completing this task on time. This paper examines how the DFPP has encouraged innovation and emphasizes the importance of knowledge transfer and uptake.
Article
Medicine, General & Internal
Erika Schulte, Frank Petzke, Claudia Spies, Claudia Denke, Michael Schaefer, Norbert Donner-Banzhoff, Ralph Hertwig, Odette Wegwarth
Summary: This study, based on physician self-reporting, reveals that some physicians experience negative emotions when faced with a patient's request for an increase in opioid dosage, which may lead to inappropriate prescribing of strong opioids. Self-awareness of physician emotions is crucial for ensuring responsible, guideline-based long-term opioid prescriptions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Jose A. A. Gonzales-Zamora, David R. R. Soriano-Moreno, Anderson N. N. Soriano-Moreno, Linda Ponce-Rosas, Lucero Sangster-Carrasco, Abraham De-Los-Rios-Pinto, Raysa M. M. Benito-Vargas, Valentina Murrieta-Ruiz, Noelia Morocho-Alburqueque, Brenda Caira-Chuquineyra, Daniel Fernandez-Guzman, Fabricio Ccami-Bernal, Carlos Quispe-Vicuna, Mariano Alarcon-Parra, Antony Pinedo-Soria, Jorge Alave
Summary: This study investigated the knowledge status of Peruvian physicians regarding mpox disease through an online survey. The results showed that most physicians had a high level of knowledge about mpox, but there were still some knowledge gaps that need to be addressed through educational campaigns, especially for physicians from the eastern region and those without clinical experience.
Article
Substance Abuse
Rozner Lihi, Delayahu Yael, Brill Silviu, Sason Anat, Weinstein Marsha, Shoshan Stacy, Schreiber Shaul, Adelson Miriam, Peles Einat
Summary: To minimize the risk of an opioid epidemic in Israel, this study evaluated physicians' knowledge, stigma, and approach to prescribing opioids, as well as their knowledge about opioid maintenance treatment (OMT) for opioid use disorder (OUD). The study found that physicians with higher knowledge levels were more likely to encounter patients with substance use disorder (SUD) and be familiar with OMT. Physicians with higher stigma levels were more likely to prescribe opioids but had limited knowledge about OMT. Physicians with higher approach levels were more likely to prescribe opioids and cannabis, have limited knowledge about OMT, and self-identify SUD.
HARM REDUCTION JOURNAL
(2023)
Article
Oncology
M. Fallon, K. Dierberger, M. Leng, P. S. Hall, S. Allende, R. Sabar, E. Verastegui, D. Gordon, L. Grant, R. Lee, K. McWillams, G. D. Murray, L. Norris, C. Reid, T. A. Sande, A. Caraceni, S. Kaasa, B. J. A. Laird
Summary: This study suggests that omitting step 2 of the WHO ladder in cancer pain management and using low-dose strong opioids as an alternative can be more efficient and cost-effective, with fewer side effects.
ANNALS OF ONCOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Chi-Yuan Kuo, Ya-Ting Chang, Yu-Ting Huang, I-Chih Ni, Mei-Hsin Chen, Chih- Wu
Summary: This study demonstrates the superior performance of molybdenum disulfide (MoS2) as a diffusion barrier and liner. The research develops a new process to efficiently prepare MoS2 and shows its effectiveness through various measurements. MoS2 exhibits better barrier properties and thermal stability compared to the current material Ta, and it acts as an excellent interface to reduce surface scattering and circuit resistance.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Oncology
Sebastiano Mercadante, Claudio Adile, Patrizia Ferrera, Maria Caterina Pallotti, Marianna Ricci, Giuseppe Bonanno, Alessandra Casuccio
Summary: This study aimed to evaluate the efficacy and adverse effects of methadone as a first-line therapy in patients receiving low doses of opioids or none. Results showed that methadone provided good analgesia with limited adverse effects and minimal opioid-induced tolerance.
Review
Surgery
Hala Muaddi, Erin Lillie, Stephanie Silva, Jori-Lee Cross, Karim Ladha, Stephen Choi, Aaron Mocon, Paul Karanicolas
Summary: This study systematically reviewed and meta-analyzed the effects of cryotherapy on closed incisions. The results showed that cryotherapy can significantly reduce postoperative pain and opioid consumption. However, it has no effect on hospital length of stay or surgical site infection rate.
Article
Biochemistry & Molecular Biology
Andrea Tinnirello, Silvia Mazzoleni, Carola Santi
Summary: Research on pain in the elderly shows conflicting results, with some studies suggesting a modest decrease in pain sensitivity and others finding a reduced pain threshold. Elderly individuals are more prone to hyperalgesia, with pathologic changes in the central nervous system affecting pain processing.
Article
Health Care Sciences & Services
Gawon Cho, Virginia W. Chang
Summary: The study found that compared to individuals with normal weight, obese adults are more likely to receive prescription analgesics for back pain. However, the likelihood of receiving pain prescriptions is associated with weight status, rather than indicating undertreatment based on weight.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Article
Biology
Alexandra Tinnermann, Christian Sprenger, Christian Buechel
Summary: This study investigated the effects of the opioid remifentanil on healthy male participants using combined corticospinal functional MRI. The results showed that opioids altered activity in regions involved in pain processing and pain modulation and coupling strength could differentiate between opioid analgesia and unspecific reductions in pain.
Article
Pharmacology & Pharmacy
Laura V. Minard, Judith Fisher, Larry Broadfield, Gordon Walsh, Ingrid Sketris
Summary: This study examined the use of opioid analgesics in end-of-life cancer patients and identified factors, trends, and patterns associated with the type and dose of opioids dispensed. The results showed that there may have been under-prescribing of opioid medications for some end-of-life cancer patients during the study period. This information can be used to increase awareness among healthcare professionals and regulatory bodies to improve pain management for end-of-life cancer patients.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Roaa Aljohani, Noha Barradah, Amnah Kashkari
Summary: This study evaluated the practices of primary care physicians in assessing patients with inflammatory back pain (IBP). The results showed that physicians had good knowledge of IBP symptoms but limited understanding of disease-specific features and had modest confidence in evaluating patients with IBP. Therefore, there is a need for educational programs and a more effective, feasible referral strategy.