Article
Geriatrics & Gerontology
Geoffrey J. Hoffman, Preeti N. Malani, Erica Solway, Matthias Kirch, Dianne C. Singer, Jeffrey T. Kullgren
Summary: The COVID-19 pandemic has led to worsened physical function and increased risk of falls, particularly impacting older individuals with reduced physical activity and social isolation. Public health interventions to address decreased physical activity and social isolation among older adults are crucial.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Nutrition & Dietetics
Jakub Mesinovic, Alexander J. Rodriguez, Mavil May Cervo, Anoohya Gandham, Cecilia L. H. Xu, Costas Glavas, Barbora de Courten, Ayse Zengin, Peter R. Ebeling, David Scott
Summary: This study aimed to investigate the effects of vitamin D supplementation on physical function, body composition, and metabolic health in overweight and obese older adults. The results showed that vitamin D supplementation had no significant effects on most physical function, body composition, and metabolic health parameters, but it improved stair climb times and waist circumference during exercise. Future research should explore the effects of vitamin D on muscle power and body composition in populations with vitamin D deficiency.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Geriatrics & Gerontology
Haocen Wang, Rumei Yang, Yang Yang, Yao Meng, Sha Li, Yun Jiang
Summary: In this study, we aimed to examine the relationship between pain and falls among Chinese older adults, as well as the association with healthcare utilization. The results showed a significant association between pain and falls, and subjective physical functioning was more strongly correlated with pain and falls compared to objective physical functioning.
Article
Geriatrics & Gerontology
Sofi Fristedt, Ann-Sofi Kammerlind, Eleonor I. Fransson, Marie Ernsth Bravell
Summary: This study aimed to investigate the associations between life-space mobility and measures of physical functioning among older men and women. Results showed that sex, physical performance (particularly balance, gait speed, and chair stand), and grip strength were significantly associated with life-space mobility.
Article
Sport Sciences
Alexander T. Carswell, Sarah Jackson, Paul Swinton, Thomas J. O'Leary, Jonathan C. Y. Tang, Samuel J. Oliver, Craig Sale, Rachel M. Izard, Neil P. Walsh, William D. Fraser, Julie P. Greeves
Summary: This study found that there are associations between serum vitamin D metabolites and physical performance. 25-hydroxyvitamin D (25(OH)D) is negatively correlated with 2.4-km run time and positively correlated with muscle power, while 1,25-dihydroxyvitamin D (1,25(OH)(2)D) is positively correlated with run time and negatively correlated with strength and muscle power. 24,25-dihydroxyvitamin D (24,25(OH)(2)D) is negatively correlated with run time. The vitamin D metabolites together explain a small portion of variance in physical performance. VDR SNPs are not associated with physical performance.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Review
Nutrition & Dietetics
Nasrin Nasimi, Zahra Sohrabi, Everson A. Nunes, Erfan Sadeghi, Sanaz Jamshidi, Zohreh Gholami, Marzieh Akbarzadeh, Shiva Faghih, Masoumeh Akhlaghi, Stuart M. Phillips
Summary: The effects of whey protein supplementation alone or with vitamin D on sarcopenia-related outcomes in older adults are uncertain. However, this meta-analysis indicates that whey protein supplementation improves physical function, while co-supplementation with vitamin D enhances lean mass gains, muscle strength, and physical function significantly.
ADVANCES IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Heike A. Bischoff-Ferrari, Gregor Freystatter, Bruno Vellas, Bess Dawson-Hughes, Reto W. Kressig, John A. Kanis, Walter C. Willett, JoAnn E. Manson, Rene Rizzoli, Robert Theiler, Lorenz C. Hofbauer, Gabriele Armbrecht, Jose A. P. da Silva, Michael Blauth, Caroline de Godoi Rezende Costa Molino, Wei Lang, Uwe Siebert, Andreas Egli, Endel J. Orav, Maud Wieczorek
Summary: Supplementing with omega-3 fatty acids may reduce the incidence of total falls among generally healthy and physically active older adults, while daily high doses of vitamin D or a home exercise program have no benefit.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Geriatrics & Gerontology
Tamer Ahmed, Carmen-Lucia Curcio, Mohammad Auais, Afshin Vafaei, Catherine M. Pirkle, Ricardo Oliveira Guerra, Fernando Gomez
Summary: This study investigated the longitudinal relationship between falls and life-space mobility in older adults. It found that individuals with lower life-space mobility were more likely to experience recurrent falls or injurious falls, especially among women, those with insufficient income, and comorbidities. However, improvements in life-space mobility were observed over time for some individuals with recurrent or injurious falls.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Sport Sciences
Alexandra Marziou, Benjamin Aubert, Charlene Couturier, Julien Astier, Clothilde Philouze, Philippe Obert, Jean-Francois Landrier, Catherine Riva
Summary: Combining physical exercise and vitamin D supplementation has beneficial effects on body weight management, glucose homeostasis, metabolic inflammation, and liver steatosis in obese mice. This combined strategy could be valuable in obesity management programs.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Geriatrics & Gerontology
Mary Waterhouse, Emma Sanguineti, Catherine Baxter, Briony Duarte Romero, Donald S. A. McLeod, Dallas R. English, Bruce K. Armstrong, Peter R. Ebeling, Gunter Hartel, Michael G. Kimlin, Rachel L. O'Connell, Hai Pham, Jolieke C. van der Pols, Alison J. Venn, Penelope M. Webb, David C. Whiteman, Rachel E. Neale
Summary: This study found that monthly high-dose vitamin D supplementation did not reduce the risk of falls, and may potentially increase the risk of falling in individuals with normal BMI. Further investigation is needed to better understand the impact of vitamin D supplementation on falls risk in different populations.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Biology
Andreas Ihle, Elvio R. Gouveia, Bruna R. Gouveia, Adilson Marques, Priscila Marconcin, Marcelo de Maio Nascimento, Maximilian Haas, Jefferson Jurema, Maria A. Tinoco, Matthias Kliegel
Summary: Experiencing a fall in old age can lead to negative effects on physical and cognitive health, as well as the ability to engage in physical activities and exercise. This study found that falls hinder physical activity engagement, thereby impeding the accumulation of cognitive reserve and resulting in lower cognitive functioning outcomes.
Article
Clinical Neurology
Sujuan Li, Xuelei Xu, Yan Qiu, Ziwei Teng, Jieyu Liu, Hui Yuan, Jindong Chen, Yuxi Tan, Min Yang, Kun Jin, Baoyan Xu, Hui Tang, Ziru Zhao, Bolun Wang, Hui Xiang, Haishan Wu
Summary: This study found that patients with bipolar disorder have higher levels of vitamin D in their serum and these levels are negatively associated with cognitive impairment. For patients with bipolar disorder, more physical activity is less beneficial to cognition than longer resting.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Nutrition & Dietetics
Yali Ling, Feng Xu, Xuedi Xia, Dexing Dai, An Xiong, Ruoman Sun, Lei Qiu, Zhongjian Xie
Summary: The combination of vitamin D and calcium has a beneficial effect in preventing falls among elderly individuals, particularly those with 25(OH)D levels lower than 50 nmol/L. Vitamin D supplementation alone does not reduce the risk of falls in elderly individuals with 25(OH)D levels higher than 50 nmol/L.
CLINICAL NUTRITION
(2021)
Article
Geriatrics & Gerontology
Jian-Yu E, Aleksandra Mihailovic, Jennifer A. Schrack, Tianjing Li, David S. Friedman, Sheila K. West, Laura N. Gitlin, Pradeep Y. Ramulu
Summary: Among visually impaired older adults, injurious falls identified prospectively over 12 months contributed to a significant decline in physical activity over a 3-year period, while minimal changes were observed in fear of falling.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Medicine, General & Internal
Kilian Rapp, Sarah E. Lamb, Patrick Roigk, Clemens Becker, Claudia Konnopka, Hans-Helmut Konig, Raphael S. Peter, Dietrich Rothenbacher, Gisela Buchele
Summary: This study evaluated a comprehensive preventive intervention for fracture prevention among older people living in rural areas in Germany. Although the program did not impact the overall incidence of fragility fractures, it did show a reduction in femoral fractures, the most common fracture type. Overall, the program has positive implications for preventing fractures in older adults.
Review
Public, Environmental & Occupational Health
Suvi T. Itkonen, Rikke Andersen, Anne K. Bjoerk, Asa Brugard Konde, Hanna Eneroth, Maijaliisa Erkkola, Kristin Holvik, Ahmed A. Madar, Haakon E. Meyer, Inge Tetens, Johanna E. Torfadottir, Birna Thorisdottir, Christel J. E. Lamberg-Allardt
Summary: There are differences in the implementation of vitamin D policies and recommendations among Nordic countries, with better status and intake in the general adult population compared to at-risk groups. Collaboration and strategies are needed to improve vitamin D levels in all Nordic countries, particularly in high-risk populations.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Suvi T. Itkonen, Essi Paivarinta, Tiina Pellinen, Hanna Viitakangas, Juha Risteli, Maijaliisa Erkkola, Christel Lamberg-Allardt, Anne-Maria Pajari
Summary: The study suggests that partial replacement of animal proteins with plant-based proteins may increase markers of bone resorption and formation among healthy adults, indicating a possible risk for bone health.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Riitta J. Sallinen, Olga Dethlefsen, Sanni Ruotsalainen, Robert D. Mills, Timo A. Miettinen, Tuija E. Jaaskelainen, Annamari Lundqvist, Eero Kyllonen, Heikki Kroger, Jaro I. Karppinen, Christel Lamberg-Allardt, Heli Viljakainen, Mari A. Kaunisto, Olli Kallioniemi
Summary: Genetic factors can affect serum 25-hydroxyvitamin D concentration, influencing the optimal intake of vitamin D. By developing a population-matched genetic risk score, personalized vitamin D supplementation was tailored to individuals predisposed to low serum 25(OH)D concentration. Electronic return of individual genetic risk, serum 25(OH)D concentrations, and factors affecting vitamin D status were used to adjust supplementation, showing potential for application in other populations and countries.
JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Jyrki K. Virtanen, Tarja Nurmi, Antti Aro, Elizabeth R. Bertone-Johnson, Elina Hypponen, Heikki Kroger, Christel Lamberg-Allardt, JoAnn E. Manson, Jaakko Mursu, Pekka Mantyselka, Sakari Suominen, Matti Uusitupa, Ari Voutilainen, Tomi-Pekka Tuomainen, Sari Hantunen
Summary: A 5-year randomized trial found that vitamin D-3 supplementation did not reduce the incidences of major cardiovascular events or invasive cancer among older adults.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Kevin D. Cashman, Mairead E. Kiely, Rikke Andersen, Ida M. Gronborg, Inge Tetens, Laura Tripkovic, Susan A. Lanham-New, Christel Lamberg-Allardt, Folasade A. Adebayo, J. Christopher Gallagher, Lynette M. Smith, Jennifer M. Sacheck, Qiushi Huang, Kimmie Ng, Chen Yuan, Edward L. Giovannucci, Kumaravel Rajakumar, Charity G. Patterson, Inger Ohlund, Torbjorn Lind, Pia Karlsland Akeson, Christian Ritz
Summary: There is an urgent need to develop vitamin D dietary recommendations for dark-skinned populations at high latitudes, as they require higher vitamin D intake to maintain serum concentrations. The study found that the required vitamin D intake for dark-skinned individuals to maintain certain serum levels is substantially higher than that for White individuals.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Food Science & Technology
Folasade A. Adebayo, Suvi T. Itkonen, Taina Ohman, Mairead Kiely, Kevin D. Cashman, Christel Lamberg-Allardt
Summary: Based on data from 20 RCTs and 20 national health surveys, high S-25(OH)D concentrations >125 nmol/L were rare, and no associated adverse effects were observed.
Review
Food Science & Technology
Linnea Barebring, Christel Lamberg-Allardt, Birna Thorisdottir, Alfons Ramel, Fredrik Soderlund, Erik Kristoffer Arnesen, Bright I. Nwaru, Jutta Dierkes, Agneta Akesson
Summary: This systematic review aimed to assess the evidence for whether habitual or different levels of experimental intake of vitamin B12 from diet and supplements is sufficient to ensure adequate B12 status in groups most susceptible to vitamin B12 deficiency. The search yielded 18 included studies, and the conclusion was that the evidence is currently insufficient to determine if or which level of B12 intake is sufficient to maintain adequate status for all included populations.
FOOD & NUTRITION RESEARCH
(2023)
Review
Food Science & Technology
Birna Thorisdottir, Erik Kristoffer Arnesen, Linnea Barebring, Jutta Dierkes, Christel Lamberg-Allardt, Alfons Ramel, Bright I. Nwaru, Fredrik Soderlund, Agneta Akesson
Summary: This study systematically reviewed the evidence for associations between legume consumption and cardiovascular disease, type 2 diabetes, and their risk factors in healthy adults. The findings suggest that while there is no clear association with the risk of cardiovascular disease and type 2 diabetes, protective effects were observed in randomized controlled trials, supporting the incorporation of legumes into diverse and healthy dietary patterns.
FOOD & NUTRITION RESEARCH
(2023)
Review
Food Science & Technology
Christel Lamberg-Allardt, Linnea Barebring, Erik Kristoffer Arnesen, Bright I. Nwaru, Birna Thorisdottir, Alfons Ramel, Fredrik Soderlund, Jutta Dierkes, Agneta Akesson
Summary: This study systematically reviewed the evidence on the effect of replacing animal protein with plant protein on cardiovascular disease (CVD) and type 2 diabetes (T2D). The results suggest that replacing animal protein with plant protein can reduce total cholesterol, low-density lipoprotein cholesterol, CVD mortality, and T2D incidence. Therefore, replacing animal protein with plant protein may be a public health strategy to lower the risk of CVD mortality and T2D.
FOOD & NUTRITION RESEARCH
(2023)
Review
Food Science & Technology
Jutta Dierkes, Bright I. Nwaru, Alfons Ramel, Erik Kristoffer Arnesen, Birna Thorisdottir, Christel Lamberg-Allardt, Ulrike Spielau, Fredrik Soderlund, Linnea Barebring, Agneta Akesson
Summary: This systematic review examines the evidence on the effects of high fiber intake on growth, iron status, and bowel function in children aged 0-5 years, and finds no clear association between high fiber intake and these outcomes.
FOOD & NUTRITION RESEARCH
(2023)
Review
Food Science & Technology
Erik Kristoffer Arnesen, Birna Thorisdottir, Linnea Barebring, Fredrik Soderlund, Bright I. Nwaru, Ulrike Spielau, Jutta Dierkes, Alfons Ramel, Christel Lamberg-Allardt, Agneta Akesson
Summary: This study aimed to evaluate the relationship between nuts/seeds consumption and cardiometabolic diseases among adults. The results showed that high consumption of nuts/seeds was associated with a lower risk of cardiovascular diseases, particularly coronary heart disease. However, there was no significant association with type 2 diabetes. This study provides important insights into the effects of nuts/seeds on cardiovascular health.
FOOD & NUTRITION RESEARCH
(2023)
Review
Food Science & Technology
Linnea Barebring, Bright Nwaru, Christel Lamberg-Allardt, Birna Thorisdottir, Alfons Ramel, Fredrik Soderlund, Erik Kristoffer Arnesen, Jutta Dierkes, Agneta Akesson
Summary: Supplementation with long chain n-3 fatty acids during pregnancy can reduce the risk of asthma/wheeze in children, but has no effects on other outcomes. Supplementation during lactation or infancy does not have any effects on any outcomes. No conclusion can be made for the effects of long chain n-3 fatty acid supplementation during pregnancy for other atopic diseases or for supplementation during lactation or infancy for any outcome.
FOOD & NUTRITION RESEARCH
(2022)
Review
Food Science & Technology
Bright I. Nwaru, Jutta Dierkes, Alfons Ramel, Erik Kristoffer Arnesen, Birna Thorisdottir, Christel Lamberg-Allardt, Fredrik Soderlund, Linnea Barebring, Agneta Akesson
Summary: This study synthesized evidence from multiple studies and found no clear association between intake of different classes of fatty acids and the risk of Alzheimer's disease (AD) and dementia. The results of studies on saturated fatty acids (SFAs) and trans fatty acids (TFAs) were contradictory, while intake of polyunsaturated fatty acids (PUFAs) was associated with a decreased risk of AD.
FOOD & NUTRITION RESEARCH
(2022)
Review
Nutrition & Dietetics
Md Zahirul Islam, Nizamul Hoque Bhuiyan, Mohammed Akhtaruzzaman, Christel Lamberg Allardt, Mikael Fogelholm
Summary: Vitamin D deficiency is a significant global public health problem, and there is a high prevalence of severe deficiency in different population groups in Bangladesh, especially among the elderly and women. Underlying factors for this include dark skin colour, homebound and sedentariness, insufficient sunlight exposure, atmospheric pollution, clothing style, obesity, use of sunscreen, and no supplementation. A comprehensive strategy is needed to address the health consequences of vitamin D deficiency.
ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Food Science & Technology
Erik Kristoffer Arnesen, Birna Thorisdottir, Christel Lamberg-Allardt, Linnea Barebring, Bright Nwaru, Jutta Dierkes, Alfons Ramel, Agneta Akesson
Summary: The aim of this study was to examine the association between dietary protein intake in children and growth, as well as the risk of overweight or obesity. The study included 21 studies and found a positive association between total protein intake and BMI. In healthy Western children, early high protein intake may be causally related to higher BMI later in childhood.
FOOD & NUTRITION RESEARCH
(2022)
