Molecular Mechanisms for Biliary Phospholipid and Drug Efflux Mediated by ABCB4 and Bile Salts

Functional analysis ofABCB4mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity

(2014) Raquel Gordo-Gilart et al.   GUT

Phosphorylation of ABCB4 impacts its function: Insights from disease-causing mutations

(2014) Julien Gautherot et al.   HEPATOLOGY

ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1

(2013) Masato Ishigami et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Molecular mechanistic explanation for the spectrum of cholestatic disease caused by the S320F variant of ABCB4

(2013) Edward J. Andress et al.   HEPATOLOGY

Peroxisome proliferator-activated receptor α activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion

(2013) Nisanne S. Ghonem et al.   HEPATOLOGY

Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes

(2013) Shin-ya Morita et al.   JOURNAL OF LIPID RESEARCH

Specific and sensitive enzymatic measurement of sphingomyelin in cultured cells

(2012) Shin-ya Morita et al.   CHEMISTRY AND PHYSICS OF LIPIDS

ABCB4/MDR3 gene mutations and cholangiocarcinomas

(2012) David Tougeron et al.   JOURNAL OF HEPATOLOGY

Complementary Functions of the Flippase ATP8B1 and the Floppase ABCB4 in Maintaining Canalicular Membrane Integrity

(2011) Annemiek Groen et al.   GASTROENTEROLOGY

Effects of Cellular, Chemical, and Pharmacological Chaperones on the Rescue of a Trafficking-defective Mutant of the ATP-binding Cassette Transporter Proteins ABCB1/ABCB4

(2011) Julien Gautherot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional analysis of two isoforms of phosphatidylethanolamine N-methyltransferase

(2010) Shin-ya Morita et al.   BIOCHEMICAL JOURNAL

Itraconazole-Induced Cholestasis: Involvement of the Inhibition of Bile Canalicular Phospholipid Translocator MDR3/ABCB4

(2010) T. Yoshikado et al.   MOLECULAR PHARMACOLOGY

A lipid matrix model of membrane raft structure

(2010) Peter J. Quinn   PROGRESS IN LIPID RESEARCH

Lipid dependence of ABC transporter localization and function

(2009) Karin Klappe et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Receptor for activated C-kinase 1 regulates the cellular localization and function ofABCB4

(2009) Yuki Ikebuchi et al.   HEPATOLOGY RESEARCH

Specific and Slow Inhibition of the Kir2.1 K+Channel by Gambogic Acid

(2009) Elena Zaks-Makhina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation

(2009) Kohjiro Nagao et al.   JOURNAL OF LIPID RESEARCH

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

(2009) Daniel A.P. Gutmann et al.   TRENDS IN BIOCHEMICAL SCIENCES