标题
Advanced Systems Biology Methods in Drug Discovery and Translational Biomedicine
作者
关键词
-
出版物
Biomed Research International
Volume 2013, Issue -, Pages 1-8
出版商
Hindawi Limited
发表日期
2013-09-20
DOI
10.1155/2013/742835
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Dynamic regulatory network controlling TH17 cell differentiation
- (2013) Nir Yosef et al. NATURE
- Drug target prediction using adverse event report systems: a pharmacogenomic approach
- (2012) M. Takarabe et al. BIOINFORMATICS
- Subnetwork-based analysis of chronic lymphocytic leukemia identifies pathways that associate with disease progression
- (2012) H.-Y. Chuang et al. BLOOD
- Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
- (2012) Michael J. Lee et al. CELL
- Neighbor communities in drug combination networks characterize synergistic effect
- (2012) Jun Zou et al. Molecular BioSystems
- Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
- (2012) Orit Rozenblatt-Rosen et al. NATURE
- Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
- (2012) Lawrence N Kwong et al. NATURE MEDICINE
- Hepatitis C Virus Network Based Classification of Hepatocellular Cirrhosis and Carcinoma
- (2012) Tao Huang et al. PLoS One
- Molecular signaling network complexity is correlated with cancer patient survivability
- (2012) D. Breitkreutz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systems Pharmacology: Network Analysis to Identify Multiscale Mechanisms of Drug Action
- (2011) Shan Zhao et al. Annual Review of Pharmacology and Toxicology
- A Novel Method of Transcriptional Response Analysis to Facilitate Drug Repositioning for Cancer Therapy
- (2011) G. Jin et al. CANCER RESEARCH
- Comparing Signaling Networks between Normal and Transformed Hepatocytes Using Discrete Logical Models
- (2011) J. Saez-Rodriguez et al. CANCER RESEARCH
- Interactome Networks and Human Disease
- (2011) Marc Vidal et al. CELL
- PREDICT: a method for inferring novel drug indications with application to personalized medicine
- (2011) A. Gottlieb et al. Molecular Systems Biology
- Introduction to Network Analysis in Systems Biology
- (2011) A. Ma'ayan Science Signaling
- An Introduction to Dynamical Systems
- (2011) E. A. Sobie Science Signaling
- Obtaining and Estimating Kinetic Parameters from the Literature
- (2011) S. R. Neves Science Signaling
- Developing Models in Virtual Cell
- (2011) S. R. Neves Science Signaling
- Biomedical Model Fitting and Error Analysis
- (2011) K. D. Costa et al. Science Signaling
- Exploring Off-Targets and Off-Systems for Adverse Drug Reactions via Chemical-Protein Interactome — Clozapine-Induced Agranulocytosis as a Case Study
- (2011) Lun Yang et al. PLoS Computational Biology
- A Computational and Experimental Study of the Regulatory Mechanisms of the Complement System
- (2011) Bing Liu et al. PLoS Computational Biology
- A Decade of Systems Biology
- (2010) Han-Yu Chuang et al. Annual Review of Cell and Developmental Biology
- Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis
- (2010) S. Iadevaia et al. CANCER RESEARCH
- Signal Transduction Networks in Cancer: Quantitative Parameters Influence Network Topology
- (2010) D. J. Klinke CANCER RESEARCH
- Integrated computational model of cell cycle and checkpoint reveals different essential roles of Aurora-A and Plk1 in mitotic entry
- (2010) Jun Zou et al. Molecular BioSystems
- Network medicine: a network-based approach to human disease
- (2010) Albert-László Barabási et al. NATURE REVIEWS GENETICS
- Discovery of drug mode of action and drug repositioning from transcriptional responses
- (2010) F. Iorio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathway-Based Identification of Biomarkers for Targeted Therapeutics: Personalized Oncology with PI3K Pathway Inhibitors
- (2010) J. N. Andersen et al. Science Translational Medicine
- Unveiling the role of network and systems biology in drug discovery
- (2010) Albert Pujol et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Drug Off-Target Effects Predicted Using Structural Analysis in the Context of a Metabolic Network Model
- (2010) Roger L. Chang et al. PLoS Computational Biology
- Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets
- (2010) Silpa Suthram et al. PLoS Computational Biology
- Associating Genes and Protein Complexes with Disease via Network Propagation
- (2010) Oron Vanunu et al. PLoS Computational Biology
- A human functional protein interaction network and its application to cancer data analysis
- (2010) Guanming Wu et al. GENOME BIOLOGY
- A systems approach to prion disease
- (2009) Daehee Hwang et al. Molecular Systems Biology
- Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
- (2009) Julio Saez-Rodriguez et al. Molecular Systems Biology
- The transcriptional network for mesenchymal transformation of brain tumours
- (2009) Maria Stella Carro et al. NATURE
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Dynamic modularity in protein interaction networks predicts breast cancer outcome
- (2009) Ian W Taylor et al. NATURE BIOTECHNOLOGY
- Systems pathology—taking molecular pathology into a new dimension
- (2009) Dana Faratian et al. Nature Reviews Clinical Oncology
- Mechanisms of drug combinations: interaction and network perspectives
- (2009) Jia Jia et al. NATURE REVIEWS DRUG DISCOVERY
- Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses
- (2009) I. Amit et al. SCIENCE
- Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein Interactome
- (2009) Lun Yang et al. PLoS Computational Biology
- Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts
- (2009) Jiao Li et al. PLoS Computational Biology
- Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
- (2009) Bolan Linghu et al. GENOME BIOLOGY
- A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
- (2008) Kartik M Mani et al. Molecular Systems Biology
- Network-based global inference of human disease genes
- (2008) Xuebing Wu et al. Molecular Systems Biology
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- Network model of survival signaling in large granular lymphocyte leukemia
- (2008) R. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth
- (2008) K. D. Bromberg et al. SCIENCE
- Drug Target Identification Using Side-Effect Similarity
- (2008) M. Campillos et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search