Article
Fisheries
Qin Yang, Yingrui Zhuang, Mahasweta Saha, Qiying Qiu, Defu Chen, Lirong Chang, Luyang Xiao, Gaoge Wang
Summary: In this study, a opportunistic pathogenic bacterium, Pseudomonas aeruginosa MSLj6-25, was isolated from healthy matured Saccharina japonica. The pathogenicity of P. aeruginosa MSLj6-25 was confirmed by infection assay, showing it can cause green-rotten disease. The identification and characterization of this bacterium provide important knowledge for disease diagnosis and control in S. japonica.
Article
Environmental Sciences
Xiaoxuan Yu, Huihong Du, Yuhong Huang, Xiaohan Yin, Yawen Liu, Yongyu Li, Huatai Liu, Xinhong Wang
Summary: Microplastics and antibiotics coexist in the aquatic environment, and the adsorption of antibiotics on microplastics and their impact on microorganisms are poorly understood. This study conducted in-situ aging experiments to investigate the interaction between antibiotics, microplastics, and microorganisms, and assessed the potential risks to human health. The results showed selective adsorption of antibiotics on microplastics, and the concentration of accumulated antibiotics was influenced by the type of microplastics and environmental conditions. High-throughput sequencing revealed a higher diversity of microorganisms attached to the microplastics compared to the surrounding water. Opportunistic pathogenic bacteria were found to have positive relationships with certain antibiotics on aged microplastics, indicating the potential spread of pathogens into unaffected ecosystems and human populations. The health risk quotient (HQ) suggested the potential human health risks of consuming seafood contaminated with antibiotics and microplastics. This study provides valuable insights into the synergistic effects of antibiotics, microplastics, and microorganisms on ecological and human health.
ENVIRONMENTAL POLLUTION
(2022)
Article
Infectious Diseases
Yang Yibin, Chen Yuhua, Liu Yongtao, Song Yi, Ai Xiaohui
Summary: Hirudo nipponia, also known as the leech, is important for farmers economically and for medicinal purposes, but in recent years pathogenic bacteria have been identified in leeches that pose a threat to human health. This highlights the importance of understanding zoonotic diseases for both humans and aquatic animals.
TRANSBOUNDARY AND EMERGING DISEASES
(2021)
Article
Ecology
Charles J. Mason, Michelle Peiffer, Abbi St Clair, Kelli Hoover, Gary W. Felton
Summary: The study evaluated the pathogenic tendencies of Serratia isolated from the digestive system of healthy fall armyworm larvae and its interaction with plant defenses. Results indicate that plants can facilitate the emergence of pathobionts within the gut of fall armyworm, with resident gut bacteria able to switch from a commensal to pathogenic lifestyle.
Article
Environmental Sciences
Qing Wang, Yan Xu, Lei Liu, Lin-Yun Li, Huai Lin, Xin-Yan Wu, Wen-Jing Bi, Li-Tao Wang, Da-Qing Mao, Yi Luo
Summary: This study confirmed the contribution of heavy metal selective pressure to the increase in ampicillin-resistant opportunistic pathogens in the Xiangjiang River, and found that heavy metals significantly increased the abundance of beta-lactam resistance genes carried by these pathogens.
ENVIRONMENTAL POLLUTION
(2021)
Article
Multidisciplinary Sciences
Shan Chen, Yu-Wen Su, Junjie Sun, Tingting Chen, Yuhao Zheng, Lin-Jie Sui, Shuangli Yang, Chenbin Liu, Pengcheng Wang, Tengfei Li, Qinghua Chi, Hao Sun, Jinghu Chen, Bo-Qun Xu, Zongxiong Huang, Yimin Fang
Summary: This study presents a label-free single-particle imaging approach for rapid detection of pathogenic bacteria in complex matrix. By tracking the scattering intensity variation of single particles in free solution, the morphological heterogeneity of bacteria can be identified. The manipulation of convection in free solution enables the rapid screening of low-abundance bacteria. As a proof of concept, the technique successfully differentiated positive samples within 10 minutes without using any biological reagents.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Jin Zhang, Pengya Gao, Yuan Wu, Xiaomei Yan, Changyun Ye, Weili Liang, Meiying Yan, Xuefang Xu, Hong Jiang
Summary: This study demonstrates that confocal Raman microspectroscopy combined with chemometrics can serve as a rapid, reliable, and efficient method for the detection and identification of foodborne pathogenic bacteria without any laborious pre-treatments.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Medicine, General & Internal
Junji Hosokawa-Muto, Yukiko Sassa-O'Brien, Yoshihito Fujinami, Hiroaki Nakahara
Summary: The study aimed to find suitable methods for rapid identification of causative pathogens from infected tissue samples. By comparing RDV method with next-generation sequencing, it was found that MinION sequencing is currently the method of choice for rapid identification of causative viruses from infectious samples.
Article
Engineering, Environmental
Lizheng Guo, Kun Wan, Jianwen Zhu, Chengsong Ye, Kassim Chabi, Xin Yu
Summary: VBNC bacteria are attracting attention as they cannot be detected by traditional culture-dependent methods and can resuscitate under favorable conditions. This study detected significant quantities of viable/VBNC opportunistic pathogens in full-scale DWTPs, indicating the inadequacy of traditional methods in detecting these bacteria. Development of rapid, accurate methods for detection of VBNC pathogenic bacteria in DWTPs is necessary to ensure drinking water safety.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Yongji Zhang, Yingyu Zhang, Lina Liu, Lingling Zhou, Zhiling Zhao
Summary: Overuse of antibiotics accelerates the spread of resistance risk in the environment. The study investigated the effects of antibiotics on biofilm and bacteria in drinking water supply systems. Results showed that antibiotics can enhance bacterial resistance to chlorine and alter the biofilm community structure. Antibiotic resistant genes (ARGs) were correlated with biofilm community structure, indicating the potential for enhanced resistance in effluent bacteria.
ENVIRONMENTAL POLLUTION
(2021)
Article
Multidisciplinary Sciences
Barbra Tuhamize, Benon B. Asiimwe, Kennedy Kasaza, Wilber Sabiiti, Mathew Holden, Joel Bazira
Summary: This study found that a high percentage of Escherichia coli strains isolated from humans and livestock in rural south western Uganda carry the blaKPC gene, with a significant proportion of strains not actively expressing the gene. The results suggest that besides the KPC gene, other mechanisms may be involved in carbapenem resistance.
Article
Microbiology
Mariana Fernandes, Maria Joao Azevedo, Carla Campos, Ana Filipa Ferreira, Alvaro Azevedo, Ines Falcao-Pires, Egija Zaura, Carla Ramalho, Joana Campos, Benedita Sampaio-Maia
Summary: In early life, maternal factors such as saliva and breastmilk colonization, cardiovascular risk factors, type of delivery, oral health, and caregiving habits play a crucial role in the acquisition of oral microbiome. This study examined the prevalence of potential pathogenic and opportunistic oral bacteria in early life and found a high concordance between mother and child samples, especially in the healthy group. Factors like breastfeeding and mode of delivery were associated with specific types of oral bacteria colonization. This study highlights the importance of maternal factors in the acquisition of oral bacteria and its potential implications for children's health.
Article
Environmental Sciences
Ana Monteiro, Beatriz Almeida, Ines Paciencia, Joao Cavaleiro Rufo, Edna Ribeiro, Elisabete Carolino, Carla Viegas, Antonio Sousa Uva, Sandra Cabo Verde
Summary: This study aimed to assess the airborne bioburden in rural and urban Portuguese Primary Health Care Centers (PHCC) and found that urban PHCC had higher levels of bacterial contamination in the air compared to rural PHCC. Additionally, some indoor air quality criteria were not met in certain sampling locations in rural PHCC.
Article
Environmental Sciences
S. Kumar, R. Anwer, A. Sehrawat, N. Sehrawat, M. Yadav, A. K. Sharma
Summary: This study conducted bacteriological analyses of water samples from different drinking stations and found high levels of pathogenic bacteria in drinking water, predominantly Acinetobacter junii, Enterobacter cloacae, and Pseudomonas aeruginosa. The presence of these bacteria indicates health risks associated with drinking water contamination, underscoring the importance of quality and hygiene in drinking water.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Immunology
Huijie Chen, Yuanli Zhao, Kuangxin Chen, Yulai Wei, Hongrui Luo, Yongming Li, Fei Liu, Zuoyan Zhu, Wei Hu, Daji Luo
Summary: This study investigated the pathogenic mechanism of P. shigelloides in carp through infection experiments and gene expression analysis. The results revealed the high pathogenicity of P. shigelloides and its impact on various tissues in the fish. Moreover, the study identified key immune signaling pathways involved in the response to the infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Ecology
P. Anuradha Reddy, A. Kumaraguru, P. Raghuveer Yadav, A. Ramyashree, Jyotsna Bhagavatula, Sisinthy Shivaji
EUROPEAN JOURNAL OF WILDLIFE RESEARCH
(2011)
Article
Biochemistry & Molecular Biology
Pulala Raghuveer Yadav, Syed Hussain Basha, Pavan Kumar Pindi
Summary: Carbonic anhydrases play important roles in various functions such as carbon assimilation, pH regulation, respiration, and photosynthesis. This study investigates the atomic level details of the enzyme's mode of action and reveals that the interaction between Glu106 and Thr199 is crucial for its activity. Additionally, the protein's secondary structure elements decrease with changes in pH conditions.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Biochemistry & Molecular Biology
Pulala Raghuveer Yadav, Syed Hussain Basha, Sadam D. V. Satyanarayana, Pavan Kumar Pindi
Summary: Fluorosis is a chronic condition caused by overexposure to fluoride, affecting dental, skeletal, and non-skeletal health. Recent studies have shown that Tamarind fruit extract, specifically the compound (+)-catechin, can reduce fluoride toxicity by targeting carbonic anhydrase II.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Biochemistry & Molecular Biology
Pulala Raghuveer Yadav, Syed Hussain Basha
Summary: Fluoride ion channels of the Fluc family are crucial in combating environmental fluoride toxicity, with the functionality of the channel protein depending on specific residues at particular positions; the phenylalanines play a key role in F- transportation through the channel, and mutations at F80 and F83 to methionine have different impacts on channel activity.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Article
Environmental Sciences
P. Raghuveer Yadav, Pindi Pavan Kumar
Summary: This study attempted to delineate fluoride and identify bacterial diversity in the drinking water sources of Kurnool district, India. It was found that some groundwater and surface water samples exceeded the permissible limit for fluoride concentration. Various bacterial species were identified in both groundwater and surface water samples.
ASIAN JOURNAL OF WATER ENVIRONMENT AND POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Pulala Raghuveer Yadav, Hussain Basha Syed, Pavan Kumar Pindi
Summary: This study investigates the interaction between fluoride and enzymes, particularly focusing on its effect on the activity of pancreatic lipase. Through molecular docking and simulations, the researchers found that lipase is the most strongly inhibited enzyme by fluoride. The presence of fluoride ions leads to major fluctuations in lipase in a specific region associated with the movement of the substrate at the catalytic site. This study provides insights into the mechanism behind fluoride's modification of lipase activity.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Pulala Raghuveer Yadav, Mitta Raghavendra, Tokala Nageswar Rao
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
(2019)
Article
Biochemistry & Molecular Biology
Raghavendra Mitta, Ravindra Reddy Kandula, Raghuveer Yadav Pulala, Narasimha Jayaveera Korlakunta
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
(2018)
Article
Multidisciplinary Sciences
Raghavendra Mitta, Ravindra Reddy Kandula, Raghuveer Yadav Pulala, Narasimha Jayaveera Korlakunta, Uma Maheswara Rao Vattikuti
Article
Public, Environmental & Occupational Health
Mitta Raghavendra, Reddy Kandula Ravindra, Yadav Pulala Raghuveer, Jayaveera Korlakunta Narasimha, Maheswara Rao Vattikuti Uma, Polu Navakishor
Article
Environmental Sciences
Pavan Kumar Pindi, P. Raghuveer Yadav, Ashwitha Kodaparthi
POLISH JOURNAL OF ENVIRONMENTAL STUDIES
(2013)