Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications

Nanotopography Modulates Mechanotransduction of Stem Cells and Induces Differentiation through Focal Adhesion Kinase

(2013) Benjamin Kim Kiat Teo et al.   ACS Nano

Expression of Oct4 in human embryonic stem cells is dependent on nanotopographical configuration

(2013) Yen P. Kong et al.   Acta Biomaterialia

Spatial patterning of endothelium modulates cell morphology, adhesiveness and transcriptional signature

(2013) Ngan F. Huang et al.   BIOMATERIALS

Nanotopographical Cues Augment Mesenchymal Differentiation of Human Embryonic Stem Cells

(2013) Emmajayne Kingham et al.   Small

Nanopatterned polymer substrates promote endothelial proliferation by initiation of β-catenin transcriptional signaling

(2012) Michaela Schernthaner et al.   Acta Biomaterialia

Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires

(2012) Shu-Wen Kuo et al.   BIOMATERIALS

Nanotopography as modulator of human mesenchymal stem cell function

(2012) Karina Kulangara et al.   BIOMATERIALS

Selective functionalization of nanofiber scaffolds to regulate salivary gland epithelial cell proliferation and polarity

(2012) Shraddha I. Cantara et al.   BIOMATERIALS

Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes

(2012) Isha Paik et al.   BIOTECHNOLOGY AND BIOENGINEERING

Altered nanofeature size dictates stem cell differentiation

(2012) O. F. Zouani et al.   JOURNAL OF CELL SCIENCE

Surface modification of polycaprolactone substrates using collagen-conjugated poly(methacrylic acid) brushes for the regulation of cell proliferation and endothelialisation

(2012) Shaojun Yuan et al.   JOURNAL OF MATERIALS CHEMISTRY

Biomimetic microtopography to enhance osteogenesis in vitro

(2011) Andrew Wilkinson et al.   Acta Biomaterialia

Combined chemical and topographical guidance cues for directing cytoarchitectural polarization in primary neurons

(2011) Adrienne C. Greene et al.   BIOMATERIALS

Acceleration of neuronal precursors differentiation induced by substrate nanotopography

(2011) Elisa Migliorini et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biocompatible and Bioactive Surface Modifications for Prolonged In Vivo Efficacy

(2011) Steven R. Meyers et al.   CHEMICAL REVIEWS

Generation of primary hepatocyte microarrays by piezoelectric printing

(2011) Alicja Zarowna-Dabrowska et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair

(2011) Simon W. Moore et al.   Developmental Neurobiology

Microtopographical assembly of cardiomyocytes

(2011) Anuj A. Patel et al.   Integrative Biology

Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions

(2011) K. Saha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An algorithm-based topographical biomaterials library to instruct cell fate

(2011) H. V. Unadkat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomimetic formation of apatite on the surface of porous gelatin/bioactive glass nanocomposite scaffolds

(2010) Masoud Mozafari et al.   APPLIED SURFACE SCIENCE

Synergistically Enhanced Osteogenic Differentiation of Human Mesenchymal Stem Cells by Culture on Nanostructured Surfaces with Induction Media

(2010) Mi-Hyeon You et al.   BIOMACROMOLECULES

Direct Microfabrication of Topographical and Chemical Cues for the Guided Growth of Neural Cell Networks on Polyamidoamine Hydrogels

(2010) Gabriel Dos Reis et al.   MACROMOLECULAR BIOSCIENCE

Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells

(2010) Zara Melkoumian et al.   NATURE BIOTECHNOLOGY

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

(2010) Ying Mei et al.   NATURE MATERIALS

Controlling Cell Behavior Through the Design of Polymer Surfaces

(2010) Natália M. Alves et al.   Small

Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord

(2009) Aaron J. Krych et al.   Acta Biomaterialia

Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells

(2009) Terje Sjöström et al.   Acta Biomaterialia

Reactive Imprint Lithography: Combined Topographical Patterning and Chemical Surface Functionalization of Polystyrene-block-poly(tert-butyl acrylate) Films

(2009) Joost Duvigneau et al.   ADVANCED FUNCTIONAL MATERIALS

Nonthermal Plasma Technology as a Versatile Strategy for Polymeric Biomaterials Surface Modification: A Review

(2009) Tim Desmet et al.   BIOMACROMOLECULES

Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients

(2009) Deok-Ho Kim et al.   BIOMATERIALS

Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering

(2009) Xiaohua Liu et al.   BIOMATERIALS

Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium

(2009) Magdalena M. Mahlstedt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

Influence of the Plasma Sheath on Plasma Polymer Deposition in Advance of a Mask and down Pores

(2009) Mischa Zelzer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Increased FGF-2 secretion and ability to support neurite outgrowth by astrocytes cultured on polyamide nanofibrillar matrices

(2009) Roberto Delgado-Rivera et al.   MATRIX BIOLOGY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cell fate dictated solely by altered nanotube dimension

(2009) S. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Manufacture of PLGA Multiple-Channel Conduits with Precise Hierarchical Pore Architectures and In Vitro/Vivo Evaluation for Spinal Cord Injury

(2009) Liumin He et al.   TISSUE ENGINEERING PART C-METHODS

A High-Throughput Assay of Cell-Surface Interactions using Topographical and Chemical Gradients

(2008) Jing Yang et al.   ADVANCED MATERIALS

The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation

(2008) Gregory T. Christopherson et al.   BIOMATERIALS

The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages

(2008) Jingwei Xie et al.   BIOMATERIALS

Improved Biomaterials for Tissue Engineering Applications: Surface Modification of Polymers

(2008) Dhirendra Katti et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Quantitative evaluation of cardiomyocyte contractility in a 3D microenvironment

(2008) Jinseok Kim et al.   JOURNAL OF BIOMECHANICS

Soluble factors from neocortical astrocytes enhance neuronal differentiation of neural progenitor cells from adult rat hippocampus on micropatterned polymer substrates

(2008) Jisun Oh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Macro-Architectures in Spinal Cord Scaffold Implants Influence Regeneration

(2008) Darice Y. Wong et al.   JOURNAL OF NEUROTRAUMA

Inverted Microcontact Printing on Polystyrene-block-Poly(tert-butyl acrylate) Films: A Versatile Approach to Fabricate Structured Biointerfaces Across the Length Scales

(2008) Anika Embrechts et al.   LANGMUIR

Biodegradable polymer tubes with lithographically controlled 3D micro- and nanotopography

(2008) K. Seunarine et al.   MICROELECTRONIC ENGINEERING

Induction of Cell Polarization and Migration by a Gradient of Nanoscale Variations in Adhesive Ligand Spacing

(2008) Marco Arnold et al.   NANO LETTERS

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

(2008) Danielle S. W. Benoit et al.   NATURE MATERIALS

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nano-Structured Cell-Adhesive and Cell-Repulsive Plasma-Deposited Coatings: Chemical and Topographical Effects on Keratinocyte Adhesion

(2008) Eloisa Sardella et al.   Plasma Processes and Polymers

Enhancement of In Vitro Capillary Tube Formation by Substrate Nanotopography

(2007) C. J. Bettinger et al.   ADVANCED MATERIALS

Chondrogenic differentiation of human mesenchymal stem cells on photoreactive polymer-modified surfaces

(2007) Likun Guo et al.   BIOMATERIALS

Chemical and topographical modification of PHBV surface to promote osteoblast alignment and confinement

(2007) H. Kenar et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A