Article
Substance Abuse
Yasmin Zakiniaeiz, Cheryl M. Lacadie, Grace Macdonald-Gagnon, Elise E. DeVito, Marc N. Potenza
Summary: Results of the study indicate differences in brain connectivity during cognitive control between individuals with CUD and healthy controls, as well as some potential differences between males and females in this process. These findings suggest that interventions targeting cognitive control in CUD should take into account both sex and diagnostic group.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Psychology, Biological
Vanessa R. Rainey, Laura Stockdale, Valerie Flores-Lamb, Ian J. Kahrilas, T'kara L. Mullins, Eva Gjorgieva, Robert G. Morrison, Rebecca L. Silton
Summary: The study found that bilinguals tend to exhibit more proactive control in inhibitory tasks, while monolinguals show more reactive control. Bilinguals displayed reduced signal during interference suppression but increased later signal, while both bilinguals and monolinguals showed increased later signal in mixed incongruent trials.
Article
Psychology, Multidisciplinary
June Kang, Yeo Eun Park, Ho-Kyoung Yoon
Summary: This study investigates the effect of colors on affective processing. The results suggest that colors have an influence on emotional information processing at the semantic level, but there is no evidence supporting an effect at the lexical processing stage.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Pharmacology & Pharmacy
Kathrine Louise Jensen, Soren Brogger Jensen, Kenneth Lindegaard Madsen
Summary: Psychostimulant use disorder is a major global health issue with no effective pharmacological treatments available. This review provides an overview of pharmacological treatments targeting different aspects of psychostimulant addiction, including the dopamine system, the glutamate system, and the severe side effects of quitting long-term use. Promising results have been found with drugs modulating the dopamine system, cognitive enhancers, and drugs targeting the glutamate system, but further research is needed for sufficient evidence of efficacy and tolerability.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Psychology, Multidisciplinary
Koyo Koizumi, Naoyasu Hirao, Haruna Yamanami, Hideki Ohira
Summary: This study investigated the negative effect of psychological stress on facial impressions. By comparing the facial images before and after a stress task through an online survey, it was found that the post-stress facial impressions were more tired, older, and irritated, while less clean-cut and healthy.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychology, Multidisciplinary
Yingli Li, Juan Du, Qingfang Song, Sina Wu, Lihong Liu
Summary: The study explored the neuropsychological processing basis of gender stereotypes associated with pink and blue colors in contemporary Chinese society. Results showed that pink-masculine stimuli elicited stronger gender stereotypical interference compared to blue-masculine stimuli, as seen in longer response times and lower accuracy in participants. ERP findings identified distinct neural processing stages for pink-masculine stimuli, shedding light on the neural mechanism underlying gender-color stereotypes in Chinese culture.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Experimental
Ronen Hershman, Yulia Levin, Joseph Tzelgov, Avishai Henik
Summary: Interference in the Stroop task is suggested to be a result of information conflict and task conflict, with the latter being influenced by stimulus readability; behavioral results show that the effect of readability on task conflict is only present when verbal responses are required; differences in pupil dilation between congruent and neutral trials are influenced by stimulus readability, with unreadable neutral stimuli showing early and sustained effects compared to readable neutral stimuli.
PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG
(2021)
Article
Clinical Neurology
Carl A. Roberts, Valentina Lorenzetti, Natalia Albein-Urios, Magdalena A. Kowalczyk, Jose M. Martinez-Gonzalez, Antonio Verdejo-Garcia
Summary: Cocaine dependence is highly comorbid with personality disorders, which can affect treatment response. Through neuroimaging, it was found that CD patients with comorbid personality disorders have different neuroanatomical characteristics, suggesting potential for different treatment targets.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Neurosciences
Xiyong Dai, Jianlong Zhang, Lei Gao, Jinming Yu, Yuanchun Li, Baoguo Du, Xiangyi Huang, Haibo Zhang
Summary: Middle-aged male alcoholic subjects exhibited significant reductions in interhemispheric and intrahemispheric functional coherence, indicating possible degeneration of system/network integration, particularly in domains related to default mode, language processing, and salience integration.
Article
Psychiatry
Kyle Woisard, Joel L. Steinberg, Liangsuo Ma, Edward Zuniga, Michael Lennon, F. Gerard Moeller
Summary: Resting state functional magnetic resonance imaging (fMRI) has been used to study the functional connectivity of brain networks in addictions. This study assessed the functional and effective connectivity of the executive control network (ECN), default mode network (DMN), and salience network (SN) in cocaine dependent subjects compared to healthy control subjects. The results showed that cocaine dependent subjects had greater effective connectivity in the right ECN to left ECN pathway and negative associations between delay discounting and effective connectivity in DMN to ECN and SN to DMN pathways.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Sheri -Michelle Koopowitz, Sarah M. Cotton, Anne Uhlmann, Kevin G. F. Thomas, Dan J. Stein
Summary: Methamphetamine abuse is associated with cognitive deficits in various domains. This study aimed to compare the executive function performance of methamphetamine-dependent individuals with and without methamphetamine-induced psychosis. The results showed that methamphetamine-induced psychosis was associated with impairments in verbal generativity and inhibition, indicating the importance of these executive function subdomains in treatment adherence and relapse prevention.
PSYCHIATRY RESEARCH
(2022)
Article
Nutrition & Dietetics
Selicia T. Mayra, Natalie Kravat, Kelly Chondropoulos, Anateresa De Leon, Carol S. Johnston
Summary: This study examines the preliminary efficacy of early time-restricted eating (eTRE) on cognitive acuity in university students. The results suggest that adherence to eTRE may lead to improved cognitive acuity in this population.
NUTRITION RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Anna H. Balleyer, Bob M. Fennis
Summary: Hedonic consumption can interfere with self-regulation, but selecting hedonic consumption under moderately stressful conditions can buffer its negative effect on self-regulation, and individuals with high self-control are more likely to choose hedonic consumption under stress.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Kota Suzuki
Summary: Sequential congruency effects were observed in event-related potential (ERP) components, with Nogo-N1 reduced by incongruent stimuli and Nogo-N2 amplitudes larger for cI than iI and iC than cC. The Go-N2 was not modulated by sequential effects, indicating it is associated with selection processing. Additionally, the Go-P3 and Nogo-P3 amplitudes were largest for cI, suggesting a relationship between ERP component timing and interaction effects.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Zaiquan Dong, Qinglian Xie, Yanling Yuan, Xiaoling Shen, Yanni Hao, Jin Li, Haizhen Xu, Weihong Kuang
Summary: Based on strain-level analysis, gut microbiota may be associated with the pathogenesis of MDD and may have potential effects on cognitive function.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Statistics & Probability
Kuang-Yao Lee, Dingjue Ji, Lexin Li, Todd Constable, Hongyu Zhao
Summary: Graphical modeling of multivariate functional data is important in various applications. In this article, we propose a new conditional graphical model that takes into account the effects of external variables on graph structure, and introduce new linear operators to extend existing methods.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
(2023)
Article
Neurosciences
Lucinda M. Sisk, Kristina M. Rapuano, May Conley, Abigail S. Greene, Corey Horien, Monica D. Rosenberg, Dustin Scheinost, R. Todd Constable, Charles E. Glatt, B. J. Casey, Dylan G. Gee
Summary: Research has shown that individuals carrying the FAAH C385A polymorphism gene exhibit network-level changes in brain connectivity distinct from non-carriers, which may be related to genetic variations in endocannabinoid signaling, and these genotype-associated neural differences may emerge at a younger age.
JOURNAL OF NEUROSCIENCE RESEARCH
(2022)
Article
Clinical Neurology
Danielle A. Goldman, Anjali Sankar, Lejla Colic, Luca Villa, Jihoon A. Kim, Brian Pittman, R. Todd Constable, Dustin Scheinost, Hilary P. Blumberg
Summary: Using a whole-brain Intrinsic Connectivity Distribution approach, hubs of brain dysfunction were identified in adolescents and young adults with Bipolar I Disorder, particularly showing higher connectivity in depressed states, which were closely related to mood symptoms and could be potential targets for early intervention.
Article
Clinical Neurology
Lejla Colic, Alexis Clark, Anjali Sankar, Durga J. Rathi, Danielle A. Goldman, Jihoon A. Kim, Luca M. Villa, E. Kale Edmiston, Elizabeth T. C. Lippard, Brian Pittman, R. Todd Constable, Carolyn M. Mazure, Hilary P. Blumberg
Summary: This study investigated the relationships among gender, childhood maltreatment, hippocampus and prefrontal gray matter structure, and clinical features in bipolar disorder (BD). The findings demonstrated significant gender-related effects of childhood maltreatment on frontotemporal structure and clinical features of BD, providing novel perspectives on the gendered effects of childhood maltreatment in BD.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2022)
Article
Neurosciences
Kangjoo Lee, Corey Horien, David O'Connor, Bronwen Garand-Sheridan, Fuyuze Tokoglu, Dustin Scheinost, Evelyn M. R. Lake, R. Todd Constable
Summary: This study investigates the impact of arousal levels indexed by pupil area on the integration of large-scale brain networks using simultaneous resting state functional magnetic resonance imaging (fMRI) and pupillometry. The results show a decrease in between-network integration and inter-subject variability at low arousal compared to high arousal, with differences occurring across regions of multiple brain networks. State-dependent changes in network integration within hub regions suggest a brain state transition characterized by global synchronization and reduced network overlaps. Arousal modulation has a brain-wide impact on high-level between-network communications. Additionally, changes in fMRI signal correlation structures and the choice of global signal regression can influence conclusions when studying arousal modulations.
Article
Multidisciplinary Sciences
Yonghyun Ha, Kartiga Selvaganesan, Baosong Wu, Kasey Hancock, Charles Rogers, Sajad Hosseinnezhadian, Gigi Galiana, R. Todd Constable
Summary: At low field MRI, the long recovery time of the RF coil results in long rising and ring-down times for the square pulse, causing distortion of the applied sinc pulse. By using the Q-factor to calculate the rising and ring-down times, the RF square pulse can be compensated with additional square pulses. A series of square pulses are applied to continuously changing amplitude of the sinc pulse. The number and amplitude of the square pulses are calculated. Experimental results show that sinc pulses can be compensated using a series of square pulses, with smoother application to the RF coil with more pulses.
Article
Multidisciplinary Sciences
Dustin Scheinost, Joseph Chang, Cheryl Lacadie, Emma Brennan-Wydra, Rachel Foster, Alexandra Boxberger, Suzanne Macari, Angelina Vernetti, R. Todd Constable, Laura R. Ment, Katarzyna Chawarska
Summary: This study investigates altered functional connectivity between the anterior insula and the whole brain in neonates with high likelihood for developing autism. The findings suggest that hypoconnectivity between the left anterior insula and left amygdala is associated with higher risk scores for social behaviors associated with autism. Additionally, the study found strong coactivation between these two areas during the third trimester of pregnancy, highlighting the potential importance of prenatal neural circuitry.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Clara F. Weber, Evelyn M. R. Lake, Stefan P. Haider, Ali Mozayan, Pratik Mukherjee, Dustin Scheinost, Nigel S. Bamford, Laura Ment, Todd Constable, Seyedmehdi Payabvash
Summary: This study evaluated the impact of age on white matter microstructure and connectome disruption in patients with Autism Spectrum Disorder (ASD). The findings showed that there is an age-dependent effect on white matter microstructure, with adolescents and young adults exhibiting ASD-related abnormalities. These abnormalities were observed in both diffusion tensor imaging (DTI) metrics and connectome edge density (ED), suggesting a more widespread involvement of the connectome in ASD compared to DTI metrics. Machine learning models were also used to predict ASD diagnoses based on DTI and ED metrics, achieving reasonable accuracy.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
John Bero, Yang Li, Aviral Kumar, Colin Humphries, Snehesh Nag, Heungyeol Lee, Woo Young Ahn, Sowon Hahn, Robert Todd Constable, Hackjin Kim, Daeyeol Lee
Summary: This study examined the interaction between myelination, cortical thickness, and resting-state functional connectivity in children aged 10 to 15. The results showed higher correlations among these measures in sensory-motor cortical areas compared to association cortical areas. These correlations were stable and not influenced by age-related changes in each measure, and regional variations reflected the hierarchy of cortical information processing.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
Danielle A. Goldman, Anjali Sankar, Alexandra Rich, Jihoon A. Kim, Brian Pittman, R. Todd Constable, Dustin Scheinost, Hilary P. Blumberg
Summary: This study aimed to identify functional connectivity differences between depressions of bipolar disorder (BD-Dep) and depressions of major depressive disorder (MDD-Dep). The results showed that there were significant differences in functional connectivity patterns between these two groups, suggesting the potential for early diagnosis and treatment strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Meeting Abstract
Clinical Neurology
Ece Eldem, Shubham Misra, Terence Quinn, Lucas Driskell, Alice Perez, Carmen Carrion, Todd Constable, Joseph Schindler, Yize Zhao, Jason Sico, Jason D. Hinman, Heather Allore, Swathi Kiran, Jubin Abutalebi, Jean-Marie Annoni, Nishant K. Mishra
Article
Clinical Neurology
Mubbahsir Sheikh, Mohamad Koubeissi, R. Todd Constable, Dennis D. Spencer, Rafeed Alkawadri
Summary: This is the first known case of profound illusionary time dilation caused by electrical cortical stimulation. The study found that stimulation of certain brain regions can alter time perception. This finding may have potential benefits for conditions involving impaired time perception.
EPILEPTIC DISORDERS
(2022)
Meeting Abstract
Neurosciences
Yihong Zhao, Martin Paulus, Kara Bagot, R. Todd Constable, Marc Potenza
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Danielle Goldman, Anjali Sankar, Lejla Colic, Luca M. Villa, Jihoon A. Kim, Brian Pittman, R. Todd Constable, Dustin Scheinost, Hilary P. Blumberg
BIOLOGICAL PSYCHIATRY
(2022)
Article
Biochemical Research Methods
Corey Horien, Kangjoo Lee, Margaret L. Westwater, Stephanie Noble, Link Tejavibulya, Teimur Kayani, R. Todd Constable, Dustin Scheinost
Summary: Large, publicly available neuroimaging datasets are increasingly common, but there are challenges related to tool options for data processing and organization. This article presents a protocol to address these barriers, with steps for dataset search and download, proper data management, practical data analysis guidelines, and instructions for data and result sharing.
