Article
Nutrition & Dietetics
Suzan J. G. Knottnerus, Dewi van Harskamp, Henk Schierbeek, Jeannette C. Bleeker, Loek L. Crefcoeur, Sacha Ferdinandusse, Johannes B. van Goudoever, Riekelt H. Houtkooper, Lodewijk IJlst, Mirjam Langeveld, Ronald J. A. Wanders, Frederic M. Vaz, Frits A. Wijburg, Gepke Visser
Summary: The study investigated the metabolic fates of MCT in healthy individuals using a C-13-labeled MCT tracer. Results showed that when provided as single energy source, 42% of MCT was converted to CO2, while in combination with carbohydrates and proteins in the diet, oxidation of MCT was higher at 62%. Furthermore, less than 1% of C-13-label was incorporated in LCFA in plasma, indicating that administered MCT underwent chain-elongation to LCT.
CLINICAL NUTRITION
(2021)
Review
Nutrition & Dietetics
Amirhossein Ramezani Ahmadi, Fatemeh Shirani, Behnazi Abiri, Mansoor Siavash, Sasan Haghighi, Mojtaba Akbari
Summary: This study aimed to evaluate the effects of omega-3 fatty acids supplementation on gene expression and serum FGF-21 levels in adults with different metabolic conditions. The results showed that omega-3 fatty acids supplementation significantly increased PPAR-gamma and PPAR-alpha gene expression, but had no significant effect on serum FGF-21 levels. Additionally, there was a dose-response relationship between omega-3 fatty acid dose and gene expression and serum FGF-21 levels.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Lingsi Zeng, Honggang Lv, Xubo Wang, Ranran Xue, Cong Zhou, Xia Liu, Hao Yu
Summary: Using Mendelian randomization (MR) analysis, this study found potential causal relationships between levels of fatty acids (FA) and the risk of depression. Specifically, oleic acid (OA) and alpha-linolenic acid (ALA) were identified as potential risk factors for depression, while adrenic acid and eicosapentaenoic acid (EPA) were found to be protective. These findings emphasize the importance of further research to investigate the underlying mechanisms that mediate the association between these fatty acids and depression risk.
FRONTIERS IN NUTRITION
(2022)
Article
Environmental Sciences
Aratrika Sarkar, Ravikumar Rajarathinam, Ranganathan Budhi Venkateshan
Summary: Nitrogen and phosphorous are crucial nutrients for the growth of cyanobacteria, affecting bloom formation by toxic species. Manipulating these nutrients can enhance lipid production in cyanobacteria. This study compared growth, pigment, and lipid production in two toxic strains and found differences in response to different nutrient combinations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Endocrinology & Metabolism
Josephine M. Kanta, Luisa Deisen, Kornelia Johann, Stephanie Holm, Annemarie Lundsgaard, Jens Lund, Markus Jaehnert, Annette Schuermann, Christoffer Clemmensen, Bente Kiens, Andreas M. Fritzen, Maximilian Kleinert
Summary: This study found that medium chain fatty acids (MCFAs) can reduce food intake in rodents and humans, but the underlying mechanisms are unknown. It was discovered that MCFAs trigger the release of hepatic factors that reduce appetite. MCFAs intake increases circulating GDF15 levels and requires the GDF15-GFRAL axis for its anorectic effect.
MOLECULAR METABOLISM
(2023)
Article
Biology
M. B. Blanco, L. K. Greene, L. N. Ellsaesser, B. Schopler, M. Davison, C. Ostrowski, P. H. Klopfer, J. Fietz, E. E. Ehmke
Summary: This study analyzed the fatty acid composition of white adipose tissue in dwarf lemurs, which were subjected to high-sugar or high-fat diets and experienced cold or warm conditions during fattening and hibernation. The results showed that dwarf lemurs fed high-sugar diets had a white adipose tissue composition more similar to wild lemurs and depleted their fat reserves better during hibernation. This highlights the importance of PUFA metabolism in the ecology of tropical hibernators.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Kamila P. Liput, Adam Lepczynski, Magdalena Ogluszka, Agata Nawrocka, Ewa Polawska, Agata Grzesiak, Brygida Slaska, Chandra S. Pareek, Urszula Czarnik, Mariusz Pierzchala
Summary: It is recommended to reduce saturated fatty acids (SFA) and increase polyunsaturated fatty acids (PUFAs) n-3 and n-6 in the diet to lower the risk of metabolic disorders. Western-type diet often contains excessive n-6 PUFAs and a high n-6/n-3 ratio. Oxylipins derived from n-3 and n-6 PUFAs play a role in inflammation, while PUFAs have varying effects on cell growth, proliferation, and neoplastic lesion progression, as observed in in vitro studies, animal models, and epidemiological studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemical Research Methods
Maria Alcoriza-Balaguer, Juan C. Garcia-Canaveras, Marta Benet, Oscar Juan-Vidal, Agustin Lahoz
Summary: FAMetA is an R package and web-based application that uses C-13 mass isotopologue profiles to estimate fatty acid metabolism. It provides comprehensive characterization of FA biosynthesis and easy-to-interpret graphical representations, allowing for insights into how cells reprogram their FA metabolism and identification of new FAs through metabolic reconstruction.
BRIEFINGS IN BIOINFORMATICS
(2023)
Article
Fisheries
Marco Martinoli, Domitilla Pulcini, Maxim Veroli, Gianluca Renzi, Sebastiana Failla, Fabrizio Capoccioni
Summary: Purslane weed as a feed for crayfish can significantly increase the n-3 PUFA and carotenoid content, benefiting crayfish nutrition without affecting growth performance. It shows promise as an ingredient in crayfish diets with added value in carotenoids and polyunsaturated fatty acids. Further research is encouraged to determine the optimal inclusion of purslane weed in sustainable crayfish diets.
AQUACULTURE RESEARCH
(2021)
Article
Chemistry, Applied
Francesco Saliu, Chiara Magoni, Anna Torelli, Radiana Cozza, Marina Lasagni, Massimo Labra
Summary: A new method using chitosan nanoaggregates as emulsifier to promote the swelling of microalgae cell wall and form a large oil-ethanol interphase area for high yield extraction of polyunsaturated fatty acids, particularly suitable for the preparation of PUFA supplements.
Article
Food Science & Technology
Yahan Zhou, Yuejie Xie, Zhongming Wang, Cao Wang, Qiang Wang
Summary: A novel structured lipid containing caprylic acid and docosahexaenoic acid was synthesized using an enzymatic method. The lipid showed better physical properties, high oxidation stability, and crystallization degree compared to traditional oils. It also had effects on lipid metabolism and obesity protection.
FOOD SCIENCE & NUTRITION
(2023)
Article
Chemistry, Applied
Pedro Henrique Soares Cardoso, Enya Silva de Oliveira, Luciano Morais Liao, Gerlon de Almeida Ribeiro Oliveira
Summary: This study compared the lipid profile of chicken eggs produced in conventional and free-range systems using H-1 NMR. It found that free-range eggs had higher concentrations of omega-3 and omega-6 polyunsaturated fatty acids. The study also showed that a specific signal ratio could accurately classify different samples. These findings are important for quality control and fraud prevention in the egg industry.
Article
Biochemistry & Molecular Biology
Zhi-Hong Yang, Kimball Nill, Yuki Takechi-Haraya, Martin P. Playford, David Nguyen, Zu-Xi Yu, Milton Pryor, Jingrong Tang, Krishna Vamsi Rojulpote, Nehal N. Mehta, Han Wen, Alan T. Remaley
Summary: The study found that supplementation of the Western diet with high-oleic MSO, but not CSO, reduced atherosclerosis development in LDLR-KO mice independent of changes in plasma lipids.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Damon Britton, Matthias Schmid, Andrew T. Revill, Patti Virtue, Peter D. Nichols, Catriona L. Hurd, Craig N. Mundy
Summary: Seaweeds in coastal ecosystems play a crucial role as habitats and food sources for various species. Variability in the availability of nutritional compounds of abundant understory seaweeds across different sites in eastern Tasmania is primarily driven by differences in species composition and biochemical composition.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Review
Green & Sustainable Science & Technology
Lan Wu, Wei Wei, Zhijie Chen, Bing-Jie Ni
Summary: This review article provides a systematic introduction to the formation of medium-chain fatty acids (MCFAs) through open-culture fermentation, including metabolic platforms, competitive bio-reactions, operational conditions, challenges, and potential opportunities for improving MCFAs productions biologically.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Biotechnology & Applied Microbiology
Sung-Yeoul Kim, Vikash Chandra Roy, Jin-Seok Park, Byung-Soo Chun
Summary: This study aims to extract functional substances from Undaria pinnatiida sporophyll using supercritical carbon dioxide (SC-CO2) and subcritical water extraction (SWE). The results showed that the consecutive green extraction method can yield extracts rich in fucoxanthin and beta-carotene, and the sporophyll of Undaria pinnatiida contains health-beneficial fatty acids. Additionally, SWE can extract substances with antioxidant, antibacterial, and antihypertensive activities.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2024)
