The regulatory potential of upstream open reading frames in eukaryotic gene expression

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

uPEPperoni: An online tool for upstream open reading frame location and analysis of transcript conservation

(2014) Adam Skarshewski et al.   BMC BIOINFORMATICS

Frac-seq reveals isoform-specific recruitment to polyribosomes

(2013) T. Sterne-Weiler et al.   GENOME RESEARCH

Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation

(2013) Ming-Tsung Lee et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

uORFdb—a comprehensive literature database on eukaryotic uORF biology

(2013) Klaus Wethmar et al.   NUCLEIC ACIDS RESEARCH

Extensive Transcript Diversity and Novel Upstream Open Reading Frame Regulation in Yeast

(2013) Karl Waern et al.   G3-Genes Genomes Genetics

Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

(2013) Cristina Barbosa et al.   PLoS Genetics

A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype

(2013) Gianluca Occhi et al.   PLoS Genetics

Hidden coding potential of eukaryotic genomes: nonAUG started ORFs

(2012) Alex V. Kochetov et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Peptidomic discovery of short open reading frame–encoded peptides in human cells

(2012) Sarah A Slavoff et al.   Nature Chemical Biology

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

(2012) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress

(2012) M. V. Gerashchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations

(2012) Tuan Tran et al.   Nature Communications

Short ORF-Dependent Ribosome Shunting Operates in an RNA Picorna-Like Virus and a DNA Pararetrovirus that Cause Rice Tungro Disease

(2012) Mikhail M. Pooggin et al.   PLoS Pathogens

Translational Control via Protein-Regulated Upstream Open Reading Frames

(2011) Jan Medenbach et al.   CELL

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

Transgenic zebrafish model to study translational control mediated by upstream open reading frame of human chop gene

(2011) Hung-Chieh Lee et al.   NUCLEIC ACIDS RESEARCH

An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA

(2011) F. Zhang et al.   NUCLEIC ACIDS RESEARCH

Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs

(2011) Vanda Munzarová et al.   PLoS Genetics

Marie Unna hereditary hypotrichosis: A Turkish family with loss of eyebrows and a U2HR mutation

(2010) Ayse Tulin Mansur et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

C/EBP  uORF mice--a genetic model for uORF-mediated translational control in mammals

(2010) K. Wethmar et al.   GENES & DEVELOPMENT

Marie Unna hereditary hypotrichosis: Identification of a U2HR mutation in the family from the original 1925 report

(2010) Silke Redler et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide

(2010) Shashi Bhushan et al.   MOLECULAR CELL

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

sORF finder: a program package to identify small open reading frames with high coding potential

(2009) Kousuke Hanada et al.   BIOINFORMATICS

Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast

(2009) Craig Lawless et al.   BMC GENOMICS

Identification of aU2HRgene mutation in Turkish families with Marie Unna hereditary hypotrichosis

(2009) S. Düzenli et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB

(2009) Jeske J Smink et al.   EMBO JOURNAL

Differential regulation of oestrogen receptor β isoforms by 5′ untranslated regions in cancer

(2009) Laura Smith et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A novel mutation in Hr causes abnormal hair follicle morphogenesis in hairpoor mouse, an animal model for Marie Unna Hereditary Hypotrichosis

(2009) In Cheol Baek et al.   MAMMALIAN GENOME

Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

(2009) Yaran Wen et al.   NATURE GENETICS

Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions

(2009) Yi-Jiun Chen et al.   NUCLEIC ACIDS RESEARCH

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

(2009) S. E. Calvo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans

(2009) Arun K Ramani et al.   GENOME BIOLOGY

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

(2008) Peggy Kirstetter et al.   CANCER CELL

Trans-regulation of the expression of the transcription factor MtHAP2-1 by a uORF controls root nodule development

(2008) J. P. Combier et al.   GENES & DEVELOPMENT

Phosphorylation of eIF2 DirectsATF5Translational Control in Response to Diverse Stress Conditions

(2008) Donghui Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translation of cIAP2 mRNA Is Mediated Exclusively by a Stress-Modulated Ribosome Shunt

(2008) K. W. Sherrill et al.   MOLECULAR AND CELLULAR BIOLOGY

uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs

(2008) I. P. Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA