The mechanism of the second step of pre-mRNA splicing

Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19

(2011) Liping Ren et al.   PLoS One

Assembly, disassembly and recycling

(2011) Fulvia Bono et al.   RNA Biology

The splice is right: Guarantors of fidelity in pre-mRNA splicing

(2011) D. S. Horowitz   RNA

Structural studies of the spliceosome: blind men and an elephant

(2010) Andrew J Newman et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Prp43p contains a processive helicase structural architecture with a specific regulatory domain

(2010) Hélène Walbott et al.   EMBO JOURNAL

Structural basis for the function of DEAH helicases

(2010) Yangzi He et al.   EMBO REPORTS

The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing

(2010) H. Shen et al.   GENES & DEVELOPMENT

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

(2010) Prakash Koodathingal et al.   MOLECULAR CELL

Spliceosome discards intermediates via the DEAH box ATPase Prp43p

(2010) R. M. Mayas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps

(2010) C.-K. Tseng et al.   RNA

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

(2010) R. M. Lardelli et al.   RNA

Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis

(2010) S. Bessonov et al.   RNA

Evolution of Yeast Noncoding RNAs Reveals an Alternative Mechanism for Widespread Intron Loss

(2010) Q. M. Mitrovich et al.   SCIENCE

RNA helicases at work: binding and rearranging

(2010) Eckhard Jankowsky   TRENDS IN BIOCHEMICAL SCIENCES

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Spp382p Interacts with Multiple Yeast Splicing Factors, Including Possible Regulators of Prp43 DExD/H-Box Protein Function

(2009) S. Pandit et al.   GENETICS

Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction

(2009) Y.-F. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

Insights into Branch Nucleophile Positioning and Activation from an Orthogonal Pre-mRNA Splicing System in Yeast

(2009) Duncan J. Smith et al.   MOLECULAR CELL

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

(2009) Patrizia Fabrizio et al.   MOLECULAR CELL

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

(2009) Zbigniew Warkocki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon sequences at the splice junctions affect splicing fidelity and alternative splicing

(2009) Luciana B. Crotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structural analysis of the group II intron active site and implications for the spliceosome

(2009) K. S. Keating et al.   RNA

Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps

(2009) M. A. Mefford et al.   RNA

The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay

(2009) Niels H. Gehring et al.   PLOS BIOLOGY

Spliceosomal immunophilins

(2008) Annia Mesa et al.   FEBS LETTERS

A Conformational Rearrangement in the Spliceosome Sets the Stage for Prp22-Dependent mRNA Release

(2008) Beate Schwer   MOLECULAR CELL

Isolation of an active step I spliceosome and composition of its RNP core

(2008) Sergey Bessonov et al.   NATURE

Is the spliceosome a ribonucleoprotein enzyme?

(2008) John Abelson   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Both Catalytic Steps of Nuclear Pre-mRNA Splicing Are Reversible

(2008) C.-K. Tseng et al.   SCIENCE